18
Views
24
CrossRef citations to date
0
Altmetric
Original Article

Alcohol-Induced Hepatotoxicity: A Role for Oxygen Free Radicals

&
Pages 19-26 | Received 21 Jul 1986, Published online: 07 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Pushpendra Kumar Jain, Murlidhar Kharya & Asmita Gajbhiye. (2013) Pharmacological evaluation of mangiferin herbosomes for antioxidant and hepatoprotection potential against ethanol induced hepatic damage. Drug Development and Industrial Pharmacy 39:11, pages 1840-1850.
Read now
Lars H. Breimer. (1991) Invited Review: Repair of DNA Damage Induced by Reactive Oxygen Species. Free Radical Research Communications 14:3, pages 159-171.
Read now
H. Remmer, W. Kessler, H. Einsele, Th. Hintze, G. Diaz De Toranzo, A. M. Gharaibeh & H. Frank. (1989) Ethanol Promotes Oxygen-Radical Attack on Proteins But Not on Lipids. Drug Metabolism Reviews 20:2-4, pages 219-232.
Read now

Articles from other publishers (21)

Karim Naraki, Ramin Rezaee, Habibeh Mashayekhi‐Sardoo, A. Wallace Hayes & Gholamreza Karimi. (2020) Mangiferin offers protection against deleterious effects of pharmaceuticals, heavy metals, and environmental chemicals. Phytotherapy Research 35:2, pages 810-822.
Crossref
Bo Meng, Yuanzhu Zhang, Zhuqian Wang, Qinran Ding, Jia Song & Di Wang. (2019) Hepatoprotective Effects of Morchella esculenta against Alcohol-Induced Acute Liver Injury in the C57BL/6 Mouse Related to Nrf-2 and NF- κ B Signaling . Oxidative Medicine and Cellular Longevity 2019, pages 1-12.
Crossref
Amel M Soliman, Helal S Abu-El-Zahab & Gamiaa A Alswiai. (2013) Efficacy evaluation of the protein isolated from Peganum harmala seeds as an antioxidant in liver of rats. Asian Pacific Journal of Tropical Medicine 6:4, pages 285-295.
Crossref
Arshad Ali NooraniMohan K. Kale. (2012) Pretreatment of Albino Rats with Methanolic Fruit Extract of Randia Dumetorum ( L .) Protects against Alcohol Induced Liver Damage . The Korean Journal of Physiology & Pharmacology 16:2, pages 125.
Crossref
Dharam Agarwal & Helmut SeitzCarl Oneta. 2001. Alcohol in Health and Disease. Alcohol in Health and Disease 407 426 .
Xavier Ponsoda, Roque Bort, Ramiro Jover, Marı́a José Gómez-Lechón & José V Castell. (1999) Increased toxicity of cocaine on human hepatocytes induced by ethanol: role of GSH. Biochemical Pharmacology 58:10, pages 1579-1585.
Crossref
Maria K. Aleynik, Maria Anna Leo, Semyon I. Aleynik & Charles S. Lieber. (2006) Polyenylphosphatidylcholine Opposes the Increase of Cytochrome P‐4502E1 by Ethanol and Corrects Its Iron‐Induced Decrease. Alcoholism: Clinical and Experimental Research 23:1, pages 96-100.
Crossref
K. Wirkner, B. Damme, W. Poelchen & D. Pankow. (1997) Effect of Long-Term Ethanol Pretreatment on the Metabolism of Dichloromethane to Carbon Monoxide in Rats. Toxicology and Applied Pharmacology 143:1, pages 83-88.
Crossref
Abraham P. Bautista & John J. Spitzer. (2006) Postbinge Effects of Acute Alcohol Intoxication on Hepatic Free Radical Formation. Alcoholism: Clinical and Experimental Research 20:3, pages 502-509.
Crossref
Abraham P. Bautista & Kirk E. Elliott. (1994) Acute ethanol intoxication regulates f-met-leu-phe-induced chemotaxis and superoxide release by neutrophils and Kupffer cells through modulation of the formyl peptide receptor in the rat. Life Sciences 54:11, pages 721-730.
Crossref
J.P. Teare, S.M. Greenfield, J.S. Marway, V.R. Preedy, N.A. Punchard, T.J. Peters & R.P.H. Thompson. (1993) Effect of thyroidectomy and adrenalectomy on changes in liver glutathione and malonaldehyde levels after acute ethanol injection. Free Radical Biology and Medicine 14:6, pages 655-660.
Crossref
Per Stål & Rolf Hultcrantz. (1993) Iron increases ethanol toxicity in rat liver. Journal of Hepatology 17:1, pages 108-115.
Crossref
R. Farbiszewski, A. Radecka, M. Chwiecko & A. Holownia. (1992) The effect of heparegen on antioxidant enzyme activities in ethanol-induced liver injury in rats. Alcohol 9:5, pages 403-407.
Crossref
Abraham P. Bautista, Nympha B. D'Souza, Charles H. Lang & John J. Spitzer. (2006) Modulation of F‐met‐leu‐phe Induced Chemotactic Activity and Superoxide Production by Neutrophils during Chronic Ethanol Intoxication. Alcoholism: Clinical and Experimental Research 16:4, pages 788-794.
Crossref
M. Younes & O. Strubelt. (1991) Vanadate-induced toxicity towards isolated perfused rat livers: the role of lipid peroxidation. Toxicology 66:1, pages 63-74.
Crossref
Lester A. Reinke & Paul B. McCay. 1991. Liver Pathology and Alcohol. Liver Pathology and Alcohol 133 168 .
Lars H. Breimer. (2006) Molecular mechanisms of oxygen radical carcinogenesis and mutagenesis: The role of dna base damage. Molecular Carcinogenesis 3:4, pages 188-197.
Crossref
M. Younes, H. Wagner & O. Strubelt. (1989) Enhancement of acute ethanol hepatotoxicity under conditions of low oxygen supply and ischemia/reperfusion. Biochemical Pharmacology 38:20, pages 3573-3581.
Crossref
O. Strubelt, M. Younes, T. Urch, H. Breining & R. Pentz. (1987) Hepatotoxicity of acetaldehyde in rats. Toxicology Letters 39:1, pages 77-84.
Crossref
M. Younes & O. Strubelt. (1987) Enhancement of hypoxic liver damage by ethanol. Biochemical Pharmacology 36:18, pages 2973-2977.
Crossref
O. Strubelt, M. Younes & R. Pentz. (1987) Enhancement by glutathione depletion of ethanol-induced acute hepatotoxicity in vitro and in vivo. Toxicology 45:2, pages 213-223.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.