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Original Article

Oxidation of Caffeine and Related Methylxanthines in Ascorbate and Polyphenol-Driven Fenton-Type Oxidations

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Pages 225-240 | Received 17 Aug 1995, Published online: 07 Jul 2009

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Paras Sharma, Giridhar Goudar, T. Longvah, Vinod. S. Gour, S.L. Kothari & Idrees A. Wani. (2022) Fate of Polyphenols and Antioxidant Activity of Barley during Processing. Food Reviews International 38:2, pages 163-198.
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Peeyush Chandra, Ajit Gaur & Shambhu Varma. (2011) Effect of caffeine on the intraocular pressure in patients with primary open angle glaucoma. Clinical Ophthalmology 5, pages 1623-1629.
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Vinod Kumar & G.A. Ravishankar. (2009) Current Trends in Producing Low Levels of Caffeine in Coffee Berry and Processed Coffee Powder. Food Reviews International 25:3, pages 175-197.
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Barry Halliwell, Kaicun Zhao & Matthew Whiteman. (2000) The gastrointestinal tract: A major site of antioxidant action?. Free Radical Research 33:6, pages 819-830.
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Lee Hua Long & Barry Halliwell. (2000) Coffee drinking increases levels of urinary hydrogen peroxide detected in healthy human volunteers. Free Radical Research 32:5, pages 463-467.
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Articles from other publishers (31)

Flávio V. M. de Almeida, Jose L. Diaz de Tuesta, Helder T. Gomes & Mário C. Guerreiro. (2023) Catalytic Conversion of Caffeine into Molecules of Valuable Interest Via N‐Demethylation Reaction. ChemistrySelect 8:43.
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Majid Gholami Shirkoohi, Rajeshwar D. Tyagi, Peter A. Vanrolleghem & Patrick Drogui. (2022) Modelling and optimization of psychoactive pharmaceutical caffeine removal by electrochemical oxidation process: A comparative study between response surface methodology (RSM) and adaptive neuro fuzzy inference system (ANFIS). Separation and Purification Technology 290, pages 120902.
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Sayantani Mitra, Nabanita Naskar, Kalpita Ghosh, Aparna Dutta, Susanta Lahiri, Punarbasu Chaudhuri & Abhijit Saha. (2022) Studies on radiation stability of natural caffeine. Applied Radiation and Isotopes 183, pages 110148.
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Veronika Barišić, Ivana Flanjak, Ante Lončarić, Anita Pichler, Antun Jozinović, Jurislav Babić, Drago Šubarić, Borislav Miličević & Đurđica Ačkar. (2022) Valorization of cocoa shell: Impact of high voltage electrical discharge and drying technology on properties of cocoa shell. Journal of Food Processing and Preservation 46:3.
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Md. Mahbub Alam, Md. Jadu Mia, Md. Abdullah Al Mamun, Sharmin Sultana Rakhi, Kazi A. Azam & Shishir Ghosh. (2021) C‒H activation of caffeine at triruthenium and triosmium centers. Journal of Organometallic Chemistry 944, pages 121791.
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Mingxue Li, Qiong Mei, Dandan Han, Bo Wei, Zexiu An, Haijie Cao, Ju Xie & Maoxia He. (2021) The roles of HO•, ClO• and BrO• radicals in caffeine degradation: A theoretical study. Science of The Total Environment 768, pages 144733.
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Kea-Lee Yap, Li-Ngee Ho, Soon-An Ong, Kun Guo, Yoong-Sin Oon, Yong-Por Ong & Shen-Hui Thor. (2021) Crucial roles of aeration and catalyst on caffeine removal and bioelectricity generation in a double chambered microbial fuel cell integrated electrocatalytic process. Journal of Environmental Chemical Engineering 9:1, pages 104636.
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Christoph Leisser, Thomas Stimpfl, Manuel Ruiss, Caroline Pilwachs, Julius Hienert, Andreea Fisus, Wilhelm Burgmüller, Oliver Findl & Martin Kronschläger. (2020) Caffeine Uptake into the Vitreous after Peroral Coffee Consumption. Ophthalmic Research 63:6, pages 533-540.
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Yasushi Yamazoe & Kouichi Yoshinari. (2019) Prediction of regioselectivity and preferred order of metabolisms on CYP1A2-mediated reactions part 3: Difference in substrate specificity of human and rodent CYP1A2 and the refinement of predicting system. Drug Metabolism and Pharmacokinetics 34:4, pages 217-232.
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Quincy A Edwards, Sergei M Kulikov & Leah D Garner-O’Neale. (2015) Caffeine in surface and wastewaters in Barbados, West Indies. SpringerPlus 4:1.
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Imran Iftikhar & Anna Brajter-Toth. (2015) Solution or Gas Phase? Oxidation and Radical Formation in Electrospray Ionization Mass Spectrometry (ESI MS). Electroanalysis 27:12, pages 2872-2881.
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Bernard A. Goodman & Chahan Yeretzian. 2015. Processing and Impact on Active Components in Food. Processing and Impact on Active Components in Food 567 574 .
Bernard A. Goodman & Chahan Yeretzian. 2015. Processing and Impact on Active Components in Food. Processing and Impact on Active Components in Food 559 566 .
Martin Kronschläger, Stefan Löfgren, Zhaohua Yu, Nooshin Talebizadeh, Shambhu D. Varma & Per Söderberg. (2013) Caffeine eye drops protect against UV-B cataract. Experimental Eye Research 113, pages 26-31.
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Mauren Assis Souza, Bibiana Castagna Mota, Rogério Rosa Gerbatin, Fernanda Silva Rodrigues, Mauro Castro, Michele Rechia Fighera & Luiz Fernando Freire Royes. (2013) Antioxidant activity elicited by low dose of caffeine attenuates pentylenetetrazol-induced seizures and oxidative damage in rats. Neurochemistry International 62:6, pages 821-830.
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Der‐Hang Chin, Huang‐Hsien Li, Hsiu‐Maan Kuo, Pei‐Dawn Lee Chao & Chia‐Wen Liu. (2011) Neocarzinostatin as a probe for DNA protection activity—molecular interaction with caffeine. Molecular Carcinogenesis 51:4, pages 327-338.
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V. P. Kheidorov, Yu. A. Ershov, G. Yu. Chalyi & O. V. Titorovich. (2011) Oxidation of 1,3,7-trimethylxanthine by hypochlorite ion. Russian Journal of Physical Chemistry A 85:8, pages 1358-1362.
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Shambhu D. Varma, Kavita R. Hegde & Svitlana Kovtun. (2010) Inhibition of selenite‐induced cataract by caffeine. Acta Ophthalmologica 88:7.
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Toshinori Suzuki, Hiroshi Yamamoto & Wolfgang Pfleiderer. (2010) Nitrosation of N-Methyl Derivatives of Uric Acid and Their Transnitrosation Ability to N-Acetylcysteine. Chemical and Pharmaceutical Bulletin 58:9, pages 1271-1275.
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Debashish Banerjee, Sham A. Hassarajani, Biswanath Maity, Geetha Narayan, Sandip K. Bandyopadhyay & Subrata Chattopadhyay. (2010) Comparative healing property of kombucha tea and black tea against indomethacin-induced gastric ulceration in mice: possible mechanism of action. Food & Function 1:3, pages 284.
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Nathan R. Perron & Julia L. Brumaghim. (2009) A Review of the Antioxidant Mechanisms of Polyphenol Compounds Related to Iron Binding. Cell Biochemistry and Biophysics 53:2, pages 75-100.
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Roberto Rosal, Antonio Rodríguez, José Antonio Perdigón-Melón, Alice Petre, Eloy García-Calvo, María José Gómez, Ana Agüera & Amadeo R. Fernández-Alba. (2009) Degradation of caffeine and identification of the transformation products generated by ozonation. Chemosphere 74:6, pages 825-831.
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J. Bichler, C. Cavin, T. Simic, A. Chakraborty, F. Ferk, C. Hoelzl, R. Schulte-Hermann, M. Kundi, G. Haidinger, K. Angelis & S. Knasmüller. (2007) Coffee consumption protects human lymphocytes against oxidative and 3-amino-1-methyl-5H-pyrido[4,3-b]indole acetate (Trp-P-2) induced DNA-damage: Results of an experimental study with human volunteers. Food and Chemical Toxicology 45:8, pages 1428-1436.
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Ilza Dalmázio, Leonardo S. Santos, Renata P. Lopes, Marcos N. Eberlin & Rodinei Augusti. (2005) Advanced Oxidation of Caffeine in Water:  On-Line and Real-Time Monitoring by Electrospray Ionization Mass Spectrometry. Environmental Science & Technology 39:16, pages 5982-5988.
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Ignaz J. Buerge, Thomas Poiger, Markus D. Müller & Hans-Rudolf Buser. (2003) Caffeine, an Anthropogenic Marker for Wastewater Contamination of Surface Waters. Environmental Science & Technology 37:4, pages 691-700.
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Fu-Chou Cheng, Jen-Fon Jen & Tung-Hu Tsai. (2002) Hydroxyl radical in living systems and its separation methods. Journal of Chromatography B 781:1-2, pages 481-496.
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Barry Halliwell. 2001. Handbook of Antioxidants. Handbook of Antioxidants.
Benoît Schilter, Christophe Cavin, Angelika Tritscher & Anne Constable. 2001. Coffee. Coffee 165 183 .
S. Homma. 2001. Coffee. Coffee 50 67 .
Lee Hua Long & Barry Halliwell. 2001. Flavonoids and Other Polyphenols. Flavonoids and Other Polyphenols 181 190 .
M. S. Vinchurkar, B. S. M. Rao, H. Mohan, J. P. Mittal, K. H. Schmidt & C. D. Jonah. (1997) Absorption Spectra of Isomeric OH Adducts of 1,3,7-Trimethylxanthine. The Journal of Physical Chemistry A 101:16, pages 2953-2959.
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