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Free Radical Research Volume 27, 1997 - Issue 4
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Original Article

Inhibition of NADPH Oxidase-Mediated Superoxide Radical Formation in PMA-Stimulated Human Neutrophils by 4-Hydroxynonenal– Binding to -SH and -NH2 Groups

Werner G. Siems Herzog-ulius Hospital of Rheumatology and Orthopaedics, Kurhausstraβe 13–17, 0-38655, Bad HarzburgGermany
,
Elisabetta Capuozzò Department of Biochenzical Sciences, University of Rome, P.Ie A. Moro, 1-00185, Rome, Italy
,
Daniela Verginelli Department of Biochenzical Sciences, University of Rome, P.Ie A. Moro, 1-00185, Rome, Italy
,
Costantino Salerno Laboratovy of Clinical Biochemisty University of Rome, P.Ie A. Moro, 1-00185, Rome, Italy
,
Carlo Crifo Department of Biochenzical Sciences, University of Rome, P.Ie A. Moro, 1-00185, Rome, Italy
&
Tilman Grune Clinics of Physicd Therapy and Rehabilitation, University Hospital Charité Medical Faculty of the Humboldt University, Schumannstvape 20–21, 0-10098, Berlin, Germany
Pages 353-358 | Received 03 Mar 1997, Published online: 07 Jul 2009

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Neda Tufail, Minhal Abidi, Mohd Sharib Warsi, Tasneem Kausar & Shahid M. Nayeem. (2023) Computational and physicochemical insight into 4-hydroxy-2-nonenal induced structural and functional perturbations in human low-density lipoprotein. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-16.
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Jingjing Chen, Tao Zeng, Ye Bi, Zhixia Zhong, Keqin Xie & Xiulan Zhao. (2013) Docosahexaenoic acid (DHA) attenuated paraquat induced lung damage in mice. Inhalation Toxicology 25:1, pages 9-16.
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Joanna Rybka, Daria Kupczyk, Kornelia Kędziora-Kornatowska, Hanna Pawluk, Jolanta Czuczejko, Karolina Szewczyk-Golec, Mariusz Kozakiewicz, Marco Antonioli, Livia A Carvalho & Józef Kędziora. (2011) Age-related changes in an antioxidant defense system in elderly patients with essential hypertension compared with healthy controls. Redox Report 16:2, pages 71-77.
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Hee Joon Kim, Sun-Hee Yoon, Hyun-Ok Ryu, Byung-Hak Yoon, Seongwon Choi, Sang-Kyu Ye & Myung-Hee Chung. (2007) 8-Oxo-7,8-dihydroguanosine triphosphate(8-oxoGTP) down-regulates respiratory burst of neutrophils by antagonizing GTP toward Rac, a small GTP binding protein. Free Radical Research 41:6, pages 655-662.
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Werner G. Siems, Olaf Sommerburg, John S. Hurst & Frederik J.G.M. van Kuijk. (2000) Carotenoid oxidative degradation products inhibit Na+-K+-ATPase. Free Radical Research 33:4, pages 427-435.
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Articles from other publishers (21)

Janusz P. Sikora, Jakub Karawani & Jarosław Sobczak. (2023) Neutrophils and the Systemic Inflammatory Response Syndrome (SIRS). International Journal of Molecular Sciences 24:17, pages 13469.
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Ramona Clemen, Eric Freund, Daniel Mrochen, Lea Miebach, Anke Schmidt, Bernhard H. Rauch, Jan‐Wilm Lackmann, Ulrike Martens, Kristian Wende, Michael Lalk, Mihaela Delcea, Barbara M. Bröker & Sander Bekeschus. (2021) Gas Plasma Technology Augments Ovalbumin Immunogenicity and OT‐II T Cell Activation Conferring Tumor Protection in Mice. Advanced Science 8:10.
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José Pedro Castro, Tobias Jung, Tilman Grune & Werner Siems. (2017) 4-Hydroxynonenal (HNE) modified proteins in metabolic diseases. Free Radical Biology and Medicine 111, pages 309-315.
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Marcus J. C. Long, Jesse R. Poganik, Souradyuti Ghosh & Yimon Aye. (2017) Subcellular Redox Targeting : Bridging in Vitro and in Vivo Chemical Biology . ACS Chemical Biology 12:3, pages 586-600.
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Leslie A. Hiatt, Jennifer R. McKenzie, Leila F. Deravi, Reese S. Harry, David W. Wright & David E. Cliffel. (2012) A printed superoxide dismutase coated electrode for the study of macrophage oxidative burst. Biosensors and Bioelectronics 33:1, pages 128-133.
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J. Rybka, D. Kupczyk, K. Kędziora-Kornatowska, J. Motyl, J. Czuczejko, K. Szewczyk-Golec, M. Kozakiewicz, H. Pawluk, L. A. Carvalho & J. Kędziora. (2010) Glutathione-Related Antioxidant Defense System in Elderly Patients Treated for Hypertension. Cardiovascular Toxicology 11:1, pages 1-9.
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Gabriela Ambrozova, Michaela Pekarova & Antonin Lojek. (2011) The effect of lipid peroxidation products on reactive oxygen species formation and nitric oxide production in lipopolysaccharide-stimulated RAW 264.7 macrophages. Toxicology in Vitro 25:1, pages 145-152.
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Werner Siems, Carlo Crifo, Elisabetta Capuozzo, Koji Uchida, Tilman Grune & Costantino Salerno. (2010) Metabolism of 4-hydroxy-2-nonenal in human polymorphonuclear leukocytes. Archives of Biochemistry and Biophysics 503:2, pages 248-252.
Crossref
Patricia Alonso-Fernández & Mónica de la Fuente. (2008) Marcadores inmunológicos de envejecimiento. Revista Española de Geriatría y Gerontología 43:3, pages 167-179.
Crossref
Vidosava B. Djordjević. 2004. International Review of Cytology Volume 237. International Review of Cytology Volume 237 57 89 .
Werner Siems & Tilman Grune. (2003) Intracellular metabolism of 4-hydroxynonenal. Molecular Aspects of Medicine 24:4-5, pages 167-175.
Crossref
Frederik van Kuijk, Werner Siems & Olaf Sommerburg. 2001. Handbook of Antioxidants. Handbook of Antioxidants.
Jürgen Fuchs & Lester PackerClaire Davies, David Blake & Paul Winyard. 2001. Environmental Stressors in Health and Disease. Environmental Stressors in Health and Disease.
Herman Sahlin & Håkan Nygren. (2001) Cytotoxicity Testing of Wound-Dressing Materials. Alternatives to Laboratory Animals 29:3, pages 269-275.
Crossref
Hung Nguyen, Erik Finkelstein, Abraham Reznick, Carroll Cross & Albert van der Vliet. (2001) Cigarette smoke impairs neutrophil respiratory burst activation by aldehyde-induced thiol modifications. Toxicology 160:1-3, pages 207-217.
Crossref
Cal Baier-Anderson & Robert S Anderson. (2000) Suppression of superoxide production by chlorothalonil in striped bass (Morone saxatilus) macrophages: the role of cellular sulfhydryls and oxidative stress. Aquatic Toxicology 50:1-2, pages 85-96.
Crossref
Brahm H. Segal, Thomas L. Leto, John I. Gallin, Harry L. Malech & Steven M. Holland. (2000) Genetic, Biochemical, and Clinical Features of Chronic Granulomatous Disease. Medicine 79:3, pages 170-200.
Crossref
Cal Baier-Anderson & Robert S. Anderson. (2000) The Effects of Chlorothalonil on Oyster Hemocyte Activation: Phagocytosis, Reduced Pyridine Nucleotides, and Reactive Oxygen Species Production. Environmental Research 83:1, pages 72-78.
Crossref
Lucia S. Yoshida, Shigeru Abe & Shohko Tsunawaki. (2000) Fungal Gliotoxin Targets the Onset of Superoxide-Generating NADPH Oxidase of Human Neutrophils. Biochemical and Biophysical Research Communications 268:3, pages 716-723.
Crossref
Maurizio ParolaGiorgio BellomoGaia RobinoGiuseppina BarreraMario Umberto Dianzani. (1999) 4-Hydroxynonenal As a Biological Signal: Molecular Basis and Pathophysiological Implications. Antioxidants & Redox Signaling 1:3, pages 255-284.
Crossref
Bernard M. Babior. (1999) NADPH Oxidase: An Update. Blood 93:5, pages 1464-1476.
Crossref

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