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Free Radical Research Volume 27, 1997 - Issue 4
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Original Article

Hydroxyl Radical Scavenging Activity of Nonsteroidal Anti-Inflammatory Drugs

Masanori Kataoka Research and Development Laboratories, Maruho Co. Ltd., 1–8–23, Oyodonaka, Kita-ku, Osaka, 531, Japan
,
Kazumi Tonooka Research and Development Laboratories, Maruho Co. Ltd., 1–8–23, Oyodonaka, Kita-ku, Osaka, 531, Japan
,
Takao Ando Research and Development Laboratories, Maruho Co. Ltd., 1–8–23, Oyodonaka, Kita-ku, Osaka, 531, Japan
,
Kimie Imai Department of Xenobiotic Metabolism and Disposition, Faculty of Pharmaceufical Sciences, Setsunan University, 45–1, Nagaotuge-cho, Hirakata, Osaka, 57341, Japan
&
Tachio Aimoto Department of Xenobiotic Metabolism and Disposition, Faculty of Pharmaceufical Sciences, Setsunan University, 45–1, Nagaotuge-cho, Hirakata, Osaka, 57341, Japan
Pages 419-427 | Received 21 Apr 1997, Published online: 07 Jul 2009

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Ennio Esposito, Vincenzo Di Matteo & Giuseppe Di Giovanni. (2007) Death in the substantia nigra: a motor tragedy. Expert Review of Neurotherapeutics 7:6, pages 677-697.
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K. Taguchi, T. Konishi, H. Nishikawa & S. Kitamura. (1999) Identification of human cytochrome P450 isoforms involved in the metabolism of S-2-[4-(3-methyl-2-thienyl)phenyl]propionic acid. Xenobiotica 29:9, pages 899-907.
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L. Šoltés, R. Mendichi, G. Kogan, J. Schiller, M. Stankovská & J. Arnhold. (2006) Degradative Action of Reactive Oxygen Species on Hyaluronan. Biomacromolecules 7:3, pages 659-668.
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I.M.M. Paino, V.F. Ximenes, L.M. da Fonseca, M.P.P. Kanegae, N.M. Khalil & I.L. Brunetti. (2005) Effect of therapeutic plasma concentrations of non-steroidal anti-inflammatory drugs on the production of reactive oxygen species by activated rat neutrophils. Brazilian Journal of Medical and Biological Research 38:4, pages 543-551.
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Eduarda Fernandes, David Costa, Sofia A. Toste, José L.F.C. Lima & Salette Reis. (2004) In vitro scavenging activity for reactive oxygen and nitrogen species by nonsteroidal anti-inflammatory indole, pyrrole, and oxazole derivative drugs. Free Radical Biology and Medicine 37:11, pages 1895-1905.
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Krishnamurthy Sairam, Karuppagounder S Saravanan, Rebecca Banerjee & Kochupurackal P Mohanakumar. (2003) Non-steroidal anti-inflammatory drug sodium salicylate, but not diclofenac or celecoxib, protects against 1-methyl-4-phenyl pyridinium-induced dopaminergic neurotoxicity in rats. Brain Research 966:2, pages 245-252.
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John Quilley. (2002) Insulin resistance, oxidative stress and aspirin: therapeutic implications?. Journal of Hypertension 20:7, pages 1279-1281.
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Kochupurackal P Mohanakumar, Dhanasekharan Muralikrishnan & Bobby Thomas. (2000) Neuroprotection by sodium salicylate against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity. Brain Research 864:2, pages 281-290.
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A. Klegeris, D.G. Walker & P.L. McGeer. (1999) Toxicity of human THP-1 monocytic cells towards neuron-like cells is reduced by non-steroidal anti-inflammatory drugs (NSAIDs). Neuropharmacology 38:7, pages 1017-1025.
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Tadao Konishi, Hitoshi Nishikawa, Shigeyuki Kitamura & Kiyoshi Tatsumi. (1998) Stereoselective determination of R,S-2-[4-(3-methyl-2-thienyl)phenyl]propionic acid and its taurine conjugates in dog urine by high-performance liquid chromatography. Journal of Chromatography B: Biomedical Sciences and Applications 709:1, pages 105-111.
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. (1998) Anti-Aging Medicine LiteratureWatch. Journal of Anti-Aging Medicine 1:2, pages 147-159.
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