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Drug Delivery Volume 18, 2011 - Issue 1
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Research Article

Characterizing monoclonal antibodies to antigenic domains of TCblR/CD320, the receptor for cellular uptake of transcobalamin-bound cobalamin

Wenxia JiangSchool of Graduate Studies, SUNY-Downstate Medical Center, Brooklyn, NY 11203, USA
,
Yasumi NakayamaDepartments of Medicine and Cell Biology, SUNY-Downstate Medical Center, Brooklyn, NY 11203, USA
,
Jeffrey M. SequeiraDepartments of Medicine and Cell Biology, SUNY-Downstate Medical Center, Brooklyn, NY 11203, USA
&
Edward V. QuadrosCorrespondence[email protected]
Pages 74-78 | Received 28 Jun 2010, Accepted 16 Jul 2010, Published online: 20 Sep 2010

Citations (13)

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Omar Abuyaman & Ebba Nexo. (2015) The soluble transcobalamin receptor (sCD320) is present in cerebrospinal fluid and correlates to dementia-related biomarkers tau proteins and amyloid-beta. Scandinavian Journal of Clinical and Laboratory Investigation 75:6, pages 514-518.
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Articles from other publishers (12)

William M. Pardridge. (2022) A Historical Review of Brain Drug Delivery. Pharmaceutics 14:6, pages 1283.
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Joël S. Bloch, Jeffrey M. Sequeira, Ana S. Ramírez, Edward V. Quadros & Kaspar P. Locher. (2022) Generation of nanobodies targeting the human, transcobalamin‐mediated vitamin B 12 uptake route . The FASEB Journal 36:4.
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David J. Elzi, William E. Bauta, Jamila R. Sanchez, Trisha Das, Shweta Mogare, Peter Zannes Fatland, Moises Iza, Alexander Pertsemlidis & Vivienne I. Rebel. (2021) Identification of a novel mechanism for meso‐tetra (4‐carboxyphenyl) porphyrin (TCPP) uptake in cancer cells. The FASEB Journal 35:3.
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Matthias Hoke, Martin Schillinger, Erich Minar, Georg Goliasch, Christoph J. Binder & Florian J. Mayer. (2019) Carotid ultrasound investigation as a prognostic tool for patients with diabetes mellitus. Cardiovascular Diabetology 18:1.
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Luciana Hannibal, Keerthana Bolisetty, Armend Axhemi, Patricia M. DiBello, Edward V. Quadros, Sergey Fedosov & Donald W. Jacobsen. (2018) Transcellular transport of cobalamin in aortic endothelial cells. The FASEB Journal 32:10, pages 5506-5519.
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Yuri Kinoshita, Kagayaki Nogami, Ryuta Jomura, Shin-ichi Akanuma, Hajime Abe, Masahiko Inouye, Yoshiyuki Kubo & Ken-ichi Hosoya. (2018) Investigation of Receptor-Mediated Cyanocobalamin (Vitamin B 12 ) Transport across the Inner Blood–Retinal Barrier Using Fluorescence-Labeled Cyanocobalamin . Molecular Pharmaceutics 15:8, pages 3583-3594.
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Kaveri Arora, Jeffrey M. Sequeira & Edward V. Quadros. (2017) Maternofetal transport of vitamin B 12 : role of TCblR/ CD320 and megalin . The FASEB Journal 31:7, pages 3098-3106.
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Wenxia Jiang, Yasumi Nakayama, Jeffrey M. Sequeira & Edward V. Quadros. (2013) Mapping the functional domains of TCblR/ CD320 , the receptor for cellular uptake of transcobalamin‐bound cobalamin . The FASEB Journal 27:8, pages 2988-2994.
Crossref
Edward V. Quadros & Jeffrey M. Sequeira. (2013) Cellular uptake of cobalamin: Transcobalamin and the TCblR/CD320 receptor. Biochimie 95:5, pages 1008-1018.
Crossref
Edward V. Quadros, Yasumi Nakayama & Jeffrey M. Sequeira. (2013) Saporin Conjugated Monoclonal Antibody to the Transcobalamin Receptor TCblR/CD320 Is Effective in Targeting and Destroying Cancer Cells. Journal of Cancer Therapy 04:06, pages 1074-1081.
Crossref
Johan Frederik Berg Arendt, Edward V. Quadros & Ebba Nexo. (2012) Soluble transcobalamin receptor, sCD320, is present in human serum and relates to serum cobalamin – establishment and validation of an ELISA. Clinical Chemistry and Laboratory Medicine 50:3.
Crossref
Shao-Chiang Lai, Yasumi Nakayama, Jeffrey M. Sequeira & Edward V. Quadros. (2011) Down-regulation of transcobalamin receptor TCblR/CD320 by siRNA inhibits cobalamin uptake and proliferation of cells in culture. Experimental Cell Research 317:11, pages 1603-1607.
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