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Original Articles

Self-emulsifying drug delivery system and the applications in herbal drugs

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Pages 475-486 | Accepted 30 Oct 2013, Published online: 09 Dec 2013

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (9)

Doaa H. Hassan, Amal A. Ammar, Afaf A. Ramadan & Mona K. Younis. (2023) Enhanced bioavailability and pharmacokinetics parameters of Enalapril solid self nanoemulsifying oral dispersible tablet: formulation, in vitro and in vivo evaluation. Pharmaceutical Development and Technology 28:3-4, pages 371-382.
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Eesha Shukla, Divya Dhatri Kara, Tanvi Katikala & Mahalaxmi Rathnanand. (2023) Self-nanoemulsifying drug delivery systems (SNEDDS) of anti-cancer drugs: a multifaceted nanoplatform for the enhancement of oral bioavailability. Drug Development and Industrial Pharmacy 49:1, pages 1-16.
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Swapna Poudwal & Pravin Shende. (2022) Multi-strategic approaches for enhancing active transportation using self-emulsifying drug delivery system. Journal of Drug Targeting 30:7, pages 726-736.
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Abdulrahman E Koshak, Mardi M Algandaby, Mohammad I Mujallid, Ashraf B Abdel-Naim, Nabil A Alhakamy, Usama A Fahmy, Anas Alfarsi, Shaimaa M Badr-Eldin, Thikryat Neamatallah, Mohammed Z Nasrullah, Hossam M Abdallah & Ahmed Esmat. (2021) Wound Healing Activity of Opuntia ficus-indica Fixed Oil Formulated in a Self-Nanoemulsifying Formulation. International Journal of Nanomedicine 16, pages 3889-3905.
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Yingqiu Xie, Chengling Mu, Bexultan Kazybay, Qinglei Sun, Aidana Kutzhanova, Guldan Nazarbek, Na Xu, Lazzat Nurtay, Qian Wang, Amr Amin & Xugang Li. (2021) Network pharmacology and experimental investigation of Rhizoma polygonati extract targeted kinase with herbzyme activity for potent drug delivery. Drug Delivery 28:1, pages 2187-2197.
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Hengfeng Liao, Yue Gao, Chunfang Lian, Yun Zhang, Bangyuan Wang, Yanfang Yang, Jun Ye, Yu Feng & Yuling Liu. (2019) Oral absorption and lymphatic transport of baicalein following drug–phospholipid complex incorporation in self-microemulsifying drug delivery systems. International Journal of Nanomedicine 14, pages 7291-7306.
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Sunit Kumar Sahoo, Gyanada Sankar Dash, Satyajeet Biswal, Prasanta Kumar Biswal & Prakash Chandra Senapati. (2019) Fabrication and evaluation of self-nanoemulsifying oil formulations (SNEOFs) of Efavirenz. Journal of Dispersion Science and Technology 40:3, pages 464-475.
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Yuhui Wang, Jinyang Shen, Xiaolin Yang, Ye Jin, Zhonglin Yang, Rufeng Wang, Fuming Zhang & Robert J. Linhardt. (2019) Mechanism of enhanced oral absorption of akebia saponin D by a self-nanoemulsifying drug delivery system loaded with phospholipid complex. Drug Development and Industrial Pharmacy 45:1, pages 124-129.
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Jinyang Shen, Jianping Bi, Hongli Tian, Ye Jin, Yuan Wang, Xiaolin Yang, Zhonglin Yang, Junping Kou & Fei Li. (2016) Preparation and evaluation of a self-nanoemulsifying drug delivery system loaded with Akebia saponin D–phospholipid complex. International Journal of Nanomedicine 11, pages 4919-4929.
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Articles from other publishers (35)

Popat Mohite, Anjali Joshi, Sudarshan Singh & Bhupendra Prajapati. (2023) Solubility enhancement of fexofenadine using self-nano emulsifying drug delivery system for improved biomimetic attributes. Annales Pharmaceutiques Françaises.
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Earle Radha Rani & Gadela Venkata Radha. (2023) Investigation of In Vivo Bioavailability Enhancement of Iloperidone-Loaded Solid Self-Nanoemulsifying Drug Delivery Systems: Formulation and Optimization Using Box-Behnken Design and Desirability Function. Journal of Pharmaceutical Innovation.
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R.R. Earle & V.R. Gadela. (2023) Optimization and characterization of self-nanoemulsifying drug delivery system of iloperidone using box-behnken design and desirability function. Annales Pharmaceutiques Françaises 81:1, pages 40-52.
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Gagana Velur & Raviraj Kusanur. (2022) Herbal Drugs in Cancer Treatment. Russian Journal of Bioorganic Chemistry 48:6, pages 1151-1158.
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Mizuki Ogino, Kohei Yamada, Hideyuki Sato & Satomi Onoue. (2022) Enhanced nutraceutical functions of herbal oily extract employing formulation technology: The present and future. PharmaNutrition 22, pages 100318.
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Afreen Sultana, Mina Zare, Vinoy Thomas, T.S. Sampath Kumar & Seeram Ramakrishna. (2022) Nano-based drug delivery systems: Conventional drug delivery routes, recent developments and future prospects. Medicine in Drug Discovery 15, pages 100134.
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Daniélle van Staden, Richard K. Haynes & Joe M. Viljoen. (2022) Adapting Clofazimine for Treatment of Cutaneous Tuberculosis by Using Self-Double-Emulsifying Drug Delivery Systems. Antibiotics 11:6, pages 806.
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Dávid Sinka, Enikő Doma, Nóra Szendi, Jázmin Páll, Dóra Kósa, Ágota Pető, Pálma Fehér, Zoltán Ujhelyi, Ferenc Fenyvesi, Judit Váradi, Miklós Vecsernyés, Zsolt Szűcs, Sándor Gonda, Zoltán Cziáky, Attila Kiss-Szikszai, Gábor Vasas & Ildikó Bácskay. (2022) Formulation, Characterization and Permeability Studies of Fenugreek (Trigonella foenum-graecum) Containing Self-Emulsifying Drug Delivery System (SEDDS). Molecules 27:9, pages 2846.
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Rajeev Kumar, Mohd A. Mirza, Punnoth Poonkuzhi Naseef, Mohamed Saheer Kuruniyan, Foziyah Zakir & Geeta Aggarwal. (2022) Exploring the Potential of Natural Product-Based Nanomedicine for Maintaining Oral Health. Molecules 27:5, pages 1725.
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Jing Yang, Bo Song & Junzi Wu. (2022) Herbal Nanoformulations for Asthma Treatment. Current Pharmaceutical Design 28:1, pages 46-57.
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Shaimaa A. Khalid, Kholoud K. Arafa & Ibrahim M. El-Sherbiny. 2022. Systems of Nanovesicular Drug Delivery. Systems of Nanovesicular Drug Delivery 55 68 .
Aristote B. Buya, Romano Terrasi, Jérémie K. Mbinze, Giulio G. Muccioli, Ana Beloqui, Patrick B. Memvanga & Véronique Préat. (2021) Quality-by-Design-Based Development of a Voxelotor Self-Nanoemulsifying Drug-Delivery System with Improved Biopharmaceutical Attributes. Pharmaceutics 13:9, pages 1388.
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Sandra M. Echeverry, Diana Rey, Ivonne H. Valderrama, Bibiana Verlindo de Araujo & Diana Marcela Aragón. (2021) Development of a self-emulsifying drug delivery system (SEDDS) to improve the hypoglycemic activity of Passiflora ligularis leaves extract. Journal of Drug Delivery Science and Technology 64, pages 102604.
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Shaimaa M. Badr-Eldin, Hibah M. Aldawsari, Osama A.A. Ahmed, Nabil A. Alhakamy, Thikryat Neamatallah, Solomon Z. Okbazghi & Usama A. Fahmy. (2021) Optimized semisolid self-nanoemulsifying system based on glyceryl behenate: A potential nanoplatform for enhancing antitumor activity of raloxifene hydrochloride in MCF-7 human breast cancer cells. International Journal of Pharmaceutics 600, pages 120493.
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Patcharawalai Jaisamut, Subhaphorn Wanna, Surasak Limsuwan, Sasitorn Chusri, Kamonthip Wiwattanawongsa & Ruedeekorn Wiwattanapatapee. (2020) Enhanced Oral Bioavailability and Improved Biological Activities of a Quercetin/Resveratrol Combination Using a Liquid Self-Microemulsifying Drug Delivery System. Planta Medica 87:04, pages 336-346.
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Reem Abou Assi, Ibrahim M. Abdulbaqi & Chan Siok Yee. (2021) The Evaluation of Drug Delivery Nanocarrier Development and Pharmacological Briefing for Metabolic-Associated Fatty Liver Disease (MAFLD): An Update. Pharmaceuticals 14:3, pages 215.
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Festo Damian, Mohammad Harati, Jeff Schwartzenhauer, Owen Van Cauwenberghe & Shawn D. Wettig. (2021) Challenges of Dissolution Methods Development for Soft Gelatin Capsules. Pharmaceutics 13:2, pages 214.
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Aristote B. Buya, Ana Beloqui, Patrick B. Memvanga & Véronique Préat. (2020) Self-Nano-Emulsifying Drug-Delivery Systems: From the Development to the Current Applications and Challenges in Oral Drug Delivery. Pharmaceutics 12:12, pages 1194.
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Daniélle van Staden, Jeanetta du Plessis & Joe Viljoen. (2020) Development of a Self-Emulsifying Drug Delivery System for Optimized Topical Delivery of Clofazimine. Pharmaceutics 12:6, pages 523.
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Lingzhi Wang, Wenrui Yan, Yurun Tian, Huanhuan Xue, Jiankai Tang & Liwei Zhang. (2020) Self-Microemulsifying Drug Delivery System of Phillygenin: Formulation Development, Characterization and Pharmacokinetic Evaluation. Pharmaceutics 12:2, pages 130.
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Subhashis Pal, Naresh Mittapelly, Athar Husain, Sapana Kushwaha, Sourav Chattopadhyay, Padam Kumar, Eppalapally Ramakrishna, Sudhir Kumar, Rakesh Maurya, Sabyasachi Sanyal, Jiaur R. Gayen, Prabhat R. Mishra & Naibedya Chattopadhyay. (2020) A butanolic fraction from the standardized stem extract of Cassia occidentalis L delivered by a self-emulsifying drug delivery system protects rats from glucocorticoid-induced osteopenia and muscle atrophy. Scientific Reports 10:1.
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Hemanga Hazarika, Harshita Krishnatreyya, Pronobesh Chattopadhyay, Achintya Saha, Yashwant V. Pathak & Md Kamaruz Zaman. 2020. Nano Medicine and Nano Safety. Nano Medicine and Nano Safety 267 288 .
Dilpreet Singh, Ashok K. Tiwary & Neena Bedi. (2019) Self-microemulsifying Drug Delivery System for Problematic Molecules: An Update. Recent Patents on Nanotechnology 13:2, pages 92-113.
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Kim, Kim, Lim, Kim, Yong, Choi & Jin. (2019) Comparison of 1-Palmitoyl-2-Linoleoyl-3-Acetyl-Rac-Glycerol-Loaded Self-Emulsifying Granule and Solid Self-Nanoemulsifying Drug Delivery System: Powder Property, Dissolution and Oral Bioavailability. Pharmaceutics 11:8, pages 415.
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Ranjit K. Harwansh, Rohitas Deshmukh & Md Akhlaquer Rahman. (2019) Nanoemulsion: Promising nanocarrier system for delivery of herbal bioactives. Journal of Drug Delivery Science and Technology 51, pages 224-233.
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Sabitri Bindhani, S. Mohapatra & R.K. Kar. (2019) Self Emulsifying Drug Delivery System: A Recent Approach. Asian Journal of Chemistry 31:4, pages 751-759.
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Nguyen-Thach Tung, Cao-Son Tran, Hoang-Anh Nguyen, Thuy-Duong Nguyen, Sang-Cheol Chi, Duc-Vinh Pham, Quang-Dong Bui & Xuan-Hoang Ho. (2019) Formulation and biopharmaceutical evaluation of supersaturatable self-nanoemulsifying drug delivery systems containing silymarin. International Journal of Pharmaceutics 555, pages 63-76.
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Chunxia Liu, Li Lv, Wei Guo, Lan Mo, Yaoxing Huang, Guocheng Li & Xingzhen Huang. (2018) Self-Nanoemulsifying Drug Delivery System of Tetrandrine for Improved Bioavailability: Physicochemical Characterization and Pharmacokinetic Study. BioMed Research International 2018, pages 1-10.
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Gupta Amresh, Vipin Kumar Agarwal & Chandana Venkateswara Rao. (2018) Self microemulsifying formulation of Lagerstroemia speciosa against chemically induced hepatotoxicity. Journal of Traditional and Complementary Medicine 8:1, pages 164-169.
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Vipin Kumar Agarwal, Gupta Amresh & Phool Chandra. (2018) Pharmacodynamic evaluation of self micro-emulsifying formulation of standardized extract of Lagerstroemia speciosa for antidiabetic activity. Journal of Ayurveda and Integrative Medicine 9:1, pages 38-44.
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Azin Kalantari, Dóra Kósa, Dániel Nemes, Zoltán Ujhelyi, Pálma Fehér, Miklós Vecsernyés, Judit Váradi, Ferenc Fenyvesi, Ákos Kuki, Sándor Gonda, Gábor Vasas, Rudolf Gesztelyi, Anayatollah Salimi & Ildikó Bácskay. (2017) Self-Nanoemulsifying Drug Delivery Systems Containing Plantago lanceolata—An Assessment of Their Antioxidant and Antiinflammatory Effects. Molecules 22:10, pages 1773.
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Pankaj Dangre, Ritu Gilhotra & Shashikant Dhole. (2016) Formulation and statistical optimization of self-microemulsifying drug delivery system of eprosartan mesylate for improvement of oral bioavailability. Drug Delivery and Translational Research 6:5, pages 610-621.
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Neel M. Fofaria, Hussaini Syed Sha Qhattal, Xinli Liu & Sanjay K. Srivastava. (2016) Nanoemulsion formulations for anti-cancer agent piplartine—Characterization, toxicological, pharmacokinetics and efficacy studies. International Journal of Pharmaceutics 498:1-2, pages 12-22.
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A. Saneja, N. Alam, R.D. Dubey & P.N. Gupta. 2016. Nanoarchitectonics for Smart Delivery and Drug Targeting. Nanoarchitectonics for Smart Delivery and Drug Targeting 379 404 .
Juan Wu, Shanshan Xu, Wei Jiang, Yueqing Shen & Menglu Pu. (2014) Facile preparation of a pH-sensitive nano-magnetic targeted system to deliver doxorubicin to tumor tissues. Biotechnology Letters 37:3, pages 585-591.
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