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Drug Delivery Volume 23, 2016 - Issue 3
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Research Article

Use of biorelevant media for assessment of a poorly soluble weakly basic drug in the form of liquisolid compacts: in vitro and in vivo study

Mahmoud A. BadawyResearch and Development Department, Pharmed Healthcare for Pharmaceutical Industries, Cairo, Egypt,
,
Amany O. KamelPharmaceutics and Industrial Pharmacy Department, Faculty of Pharmacy, Ain University, Cairo, Egypt, and ;School of Pharmacy, University of Waterloo, Waterloo, ON, CanadaCorrespondence[email protected]
&
Omaima A. SammourPharmaceutics and Industrial Pharmacy Department, Faculty of Pharmacy, Ain University, Cairo, Egypt, and
Pages 808-817 | Received 02 Apr 2014, Accepted 20 Apr 2014, Published online: 03 Jun 2014

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Read on this site (4)

Mei Lu, Haonan Xing, Tianzhi Yang, Jiankun Yu, Zhen Yang, Yanping Sun & Pingtian Ding. (2017) Dissolution enhancement of tadalafil by liquisolid technique. Pharmaceutical Development and Technology 22:1, pages 77-89.
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Nadia M. Morsi, Ghada A. Abdelbary, Ahmed H. Elshafeey & M. Abdallah Ahmed. (2017) Engineering of a novel optimized platform for sublingual delivery with novel characterization tools: in vitro evaluation and in vivo pharmacokinetics study in human. Drug Delivery 24:1, pages 918-931.
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Ahmed Khames. (2017) Investigation of the effect of solubility increase at the main absorption site on bioavailability of BCS class II drug (risperidone) using liquisolid technique. Drug Delivery 24:1, pages 328-338.
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Yueling Yuan, Tiange Cai, Xi Xia, Ronghua Zhang, Peter Chiba & Yu Cai. (2016) Nanoparticle delivery of anticancer drugs overcomes multidrug resistance in breast cancer. Drug Delivery 23:9, pages 3350-3357.
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Articles from other publishers (18)

Pranav Shah, Heta Desai, Bhavin Vyas, Manisha Lalan & Madhur Kulkarni. (2023) Quality-by-Design-Based Development of Rivaroxaban-Loaded Liquisolid Compact Tablets with Improved Biopharmaceutical Attributes. AAPS PharmSciTech 24:7.
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Xin Ji, Yifan Cai, Xiaochun Dong, Wei Wu & Weili Zhao. (2023) Selection of an aggregation-caused quenching-based fluorescent tracer for imaging studies in nano drug delivery systems. Nanoscale 15:21, pages 9290-9296.
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Teodora Glišić, Jelena Djuriš, Ivana Vasiljević, Jelena Parojčić & Ivana Aleksić. (2023) Application of Machine-Learning Algorithms for Better Understanding the Properties of Liquisolid Systems Prepared with Three Mesoporous Silica Based Carriers. Pharmaceutics 15:3, pages 741.
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Amira Rashad & Dina Louis. (2022) An overview on liquisolid technique: its development and applications. Therapeutic Delivery 13:12, pages 577-589.
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Murui Han, Jin Xu & Yiqing Lin. (2022) Approaches of formulation bridging in support of orally administered drug product development. International Journal of Pharmaceutics 629, pages 122380.
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Ivana Aleksić, Teodora Glišić & Jelena Parojčić. (2022) Liquisolid systems as a novel approach in formulation and manufacturing of solid dosage forms: Challenges and perspectives. Arhiv za farmaciju 72:6, pages 521-545.
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Ivana Aleksić, Teodora Glišić, Sandra Cvijić & Jelena Parojčić. (2022) Liquisolid systems: Evaluation of the influence of formulation variables on the optimum liquid load. Arhiv za farmaciju 72:1, pages 61-76.
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Ahmed M. Agiba. (2020) Liquisolid Technology: A State-of-the-Art Review on the Current State, Challenges, New and Emerging Technologies for Next Generation. Current Drug Delivery 17:9, pages 736-754.
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Nandini Chaudhary, Devika Tripathi & Awani K. Rai. (2020) A Technical Approach of Solubility Enhancement of Poorly Soluble Drugs: Liquisolid Technique. Current Drug Delivery 17:8, pages 638-650.
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Ivana Aleksić, Ilija German Ilić, Sandra Cvijić & Jelena Parojčić. (2020) An Investigation into the Influence of Process Parameters and Formulation Variables on Compaction Properties of Liquisolid Systems. AAPS PharmSciTech 21:7.
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Min‐Soo Kim & In‐hwan Baek. (2020) Pharmacokinetic analysis of mosapride following intravenous and oral administration in beagle dogs. Journal of Veterinary Pharmacology and Therapeutics 43:5, pages 454-460.
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Khalid M El-Say, Tarek A Ahmed, Osama A A Ahmed & Hanan Elimam. (2020) Enhancing the Hypolipidemic Effect of Simvastatin in Poloxamer-Induced Hyperlipidemic Rats via Liquisolid Approach: Pharmacokinetic and Pharmacodynamic Evaluation. AAPS PharmSciTech 21:6.
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Hye Jin Kim, Ji Sun Park, Se Won Yi, Minyeon Go, Hye-Ryun Kim, Su Jin Lee, Jong Min Park, Dong Hyun Cha, Sung Han Shim & Keun-Hong Park. (2020) A transport system based on a quantum dot-modified nanotracer is genetically and developmentally stable in pregnant mice. Biomaterials Science 8:12, pages 3392-3403.
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Xiaochen Liu, Dangge Wang, Pengcheng Zhang & Yaping Li. (2019) Recent advances in nanosized drug delivery systems for overcoming the barriers to anti-PD immunotherapy of cancer. Nano Today 29, pages 100801.
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Kim, Kim, Lim, Kim, Yong, Choi & Jin. (2019) Comparison of 1-Palmitoyl-2-Linoleoyl-3-Acetyl-Rac-Glycerol-Loaded Self-Emulsifying Granule and Solid Self-Nanoemulsifying Drug Delivery System: Powder Property, Dissolution and Oral Bioavailability. Pharmaceutics 11:8, pages 415.
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Yao Kang, Wen Sun, Shuyi Li, Mingle Li, Jiangli Fan, Jianjun Du, Xing‐Jie Liang & Xiaojun Peng. (2019) Oligo Hyaluronan‐Coated Silica/Hydroxyapatite Degradable Nanoparticles for Targeted Cancer Treatment. Advanced Science 6:13.
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Xingwang Zhang, Huijie Xing, Yue Zhao & Zhiguo Ma. (2018) Pharmaceutical Dispersion Techniques for Dissolution and Bioavailability Enhancement of Poorly Water-Soluble Drugs. Pharmaceutics 10:3, pages 74.
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Mei Lu, Haonan Xing, Jingzheng Jiang, Xiao Chen, Tianzhi Yang, Dongkai Wang & Pingtian Ding. (2017) Liquisolid technique and its applications in pharmaceutics. Asian Journal of Pharmaceutical Sciences 12:2, pages 115-123.
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