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Drug Delivery Volume 23, 2016 - Issue 3
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Research Article

Brain targeting by intranasal drug delivery (INDD): a combined effect of trans-neural and para-neuronal pathway

Gulam MustafaDepartment of Pharmaceutics, Faculty of Pharmacy, Hamdard University, New Delhi, India, ;College of pharmacy, Al-Dawadmi Campus, Shaqra University, Riyadh, Kingdom of Saudi Arabia,
,
Abdulmohsen H. AlrohaimiDepartment of Pharmaceutics, Faculty of Pharmacy, Hamdard University, New Delhi, India, ;College of pharmacy, Al-Dawadmi Campus, Shaqra University, Riyadh, Kingdom of Saudi Arabia,
,
Aseem BhatnagarDepartment of Nuclear Medicine Division (NMD), Institute of Nuclear Medicine & Allied Sciences, Timarpur, Timarpur, Delhi, India, and
,
Sanjula BabootaDepartment of Pharmaceutics, Faculty of Pharmacy, Hamdard University, New Delhi, India,
,
Javed AliDepartment of Pharmaceutics, Faculty of Pharmacy, Hamdard University, New Delhi, India,
&
Alka AhujaDepartment of Pharmacy, Oman Medical College, Azaiba, Muscat, Sultanate of OmanCorrespondence[email protected] [email protected]
Pages 923-929 | Received 30 Mar 2014, Accepted 07 May 2014, Published online: 24 Jun 2014

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Yueyao Jiang, Chenqi Liu, Wanchen Zhai, Ning Zhuang, Tengfei Han & Zhiying Ding. (2019) The Optimization Design Of Lactoferrin Loaded HupA Nanoemulsion For Targeted Drug Transport Via Intranasal Route. International Journal of Nanomedicine 14, pages 9217-9234.
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Ying Li, Xianpeng Fan, Wanqing Li, Peng Yang, Hui Zhang, Daoquan Tang, Xiaoxin Yin, Jianxu Sun & Aiping Zheng. (2018) Metoclopramide nasal spray in vitro evaluation and in vivo pharmacokinetic studies in dogs. Pharmaceutical Development and Technology 23:3, pages 275-281.
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Amarjitsing Rajput, Prashant Pingale & Vividha Dhapte-Pawar. (2022) Nasal delivery of neurotherapeutics via nanocarriers: Facets, aspects, and prospects. Frontiers in Pharmacology 13.
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K. Trideva Sastri, N. Vishal Gupta, Sharadha M, Souvik Chakraborty, Hitesh Kumar, Pallavi Chand, V. Balamuralidhara & D.V. Gowda. (2022) Nanocarrier facilitated drug delivery to the brain through intranasal route: A promising approach to transcend bio-obstacles and alleviate neurodegenerative conditions. Journal of Drug Delivery Science and Technology 75, pages 103656.
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Patrícia Henriques, Ana Fortuna & Slavomíra Doktorovová. (2022) Spray dried powders for nasal delivery: Process and formulation considerations. European Journal of Pharmaceutics and Biopharmaceutics 176, pages 1-20.
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Rehab Hegazy, Dina Mansour, Abeer Salama, Azza Hassan & Dalia Saleh. (2021) Exposure to intranasal chromium triggers dose and time-dependent behavioral and neurotoxicological defects in rats. Ecotoxicology and Environmental Safety 216, pages 112220.
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Patricia P. Martins, Hugh D.C. Smyth & Zhengrong Cui. (2019) Strategies to facilitate or block nose-to-brain drug delivery. International Journal of Pharmaceutics 570, pages 118635.
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Rui Li, Yuan Huang, Li Chen, Haihui Zhou, Mingwan Zhang, Lei Chang, Hong Shen, Meiling Zhou, Ping Su & Dongya Zhu. (2019) Targeted delivery of intranasally administered nanoparticles-mediated neuroprotective peptide NR2B9c to brain and neuron for treatment of ischemic stroke. Nanomedicine: Nanotechnology, Biology and Medicine 18, pages 380-390.
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Alireza Majdi, Saeed Sadigh-Eteghad, Mahnaz Talebi, Fereshteh Farajdokht, Marjan Erfani, Javad Mahmoudi & Albert Gjedde. (2018) Nicotine Modulates Cognitive Function in D-Galactose-Induced Senescence in Mice. Frontiers in Aging Neuroscience 10.
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Wenyong Tong, Chrissa A. Dwyer, Bryan E. Thacker, Charles A. Glass, Jillian R. Brown, Kristina Hamill, Kelley W. Moremen, Stéphane Sarrazin, Philip L.S.M. Gordts, Lara E. Dozier, Gentry N. Patrick, Yitzhak Tor & Jeffrey D. Esko. (2017) Guanidinylated Neomycin Conjugation Enhances Intranasal Enzyme Replacement in the Brain. Molecular Therapy 25:12, pages 2743-2752.
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Ejaj Ahmad, Yunhai Feng, Jianping Qi, Wufa Fan, Yuhua Ma, Haisheng He, Fei Xia, Xiaochun Dong, Weili Zhao, Yi Lu & Wei Wu. (2017) Evidence of nose-to-brain delivery of nanoemulsions: cargoes but not vehicles. Nanoscale 9:3, pages 1174-1183.
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Abeer Salama, Rehab Hegazy & Azza Hassan. (2016) Intranasal Chromium Induces Acute Brain and Lung Injuries in Rats: Assessment of Different Potential Hazardous Effects of Environmental and Occupational Exposure to Chromium and Introduction of a Novel Pharmacological and Toxicological Animal Model. PLOS ONE 11:12, pages e0168688.
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