3,305
Views
36
CrossRef citations to date
0
Altmetric
Research Article

In vitro and in vivo evaluation of thermosensitive chitosan hydrogel for sustained release of insulin

, , &
Pages 1028-1036 | Received 25 Mar 2014, Accepted 05 Jun 2014, Published online: 09 Jul 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Chen Li, Long Wan, Jie Luo, Mingyan Jiang & Keke Wang. (2021) Advances in Subcutaneous Delivery Systems of Biomacromolecular Agents for Diabetes Treatment. International Journal of Nanomedicine 16, pages 1261-1280.
Read now
Hanieh Gholizadeh, Shaokoon Cheng, Michele Pozzoli, Elisa Messerotti, Daniela Traini, Paul Young, Agisilaos Kourmatzis & Hui Xin Ong. (2019) Smart thermosensitive chitosan hydrogel for nasal delivery of ibuprofen to treat neurological disorders. Expert Opinion on Drug Delivery 16:4, pages 453-466.
Read now

Articles from other publishers (34)

Kumar Kulldeep Niloy & Tao L. Lowe. (2023) Injectable systems for long-lasting insulin therapy. Advanced Drug Delivery Reviews 203, pages 115121.
Crossref
Nga H.N. Do, Tuan N.A. Huynh, Tien X. Le, Anh C. Ha & Phung K. Le. (2023) Encapsulation of Triphasia trifolia extracts by pH and thermal dual-sensitive chitosan hydrogels for controlled release. Carbohydrate Polymers 320, pages 121264.
Crossref
Afshin Taheriazam, Maliheh Entezari, Zeinab Mohammadi Firouz, Shima Hajimazdarany, Mohammad Hossein Heydargoy, Amir Hossein Amin Moghadassi, Ali moghadaci, Amin sadrani, Motahhar Motahhary, Abdorrahman Harif Nashtifani, Amirhossein Zabolian, Teimour Tabari, Mehrdad Hashemi, Rasoul Raesi, Mengyuan Jiang, Xuebin Zhang, Shokooh Salimimoghadam, Yavuz Nuri Ertas & Dongdong Sun. (2023) Eco-friendly chitosan-based nanostructures in diabetes mellitus therapy: Promising bioplatforms with versatile therapeutic perspectives. Environmental Research 228, pages 115912.
Crossref
Akbar Ali, Saroj Saroj, Sunita Saha, Sanjay Kumar Gupta, Tatini Rakshit & Suchetan Pal. (2023) Glucose-Responsive Chitosan Nanoparticle/Poly(vinyl alcohol) Hydrogels for Sustained Insulin Release In Vivo . ACS Applied Materials & Interfaces.
Crossref
Yuanhui Xiang, Bo Su, Dongping Liu & Matthew J. Webber. (2023) Managing Diabetes with Hydrogel Drug Delivery. Advanced Therapeutics.
Crossref
Sema Coşkun, Serdar Onat Akbulut, Burcu Sarıkaya, Soner Çakmak & Menemşe Gümüşderelioğlu. (2022) Formulation of chitosan and chitosan-nanoHAp bioinks and investigation of printability with optimized bioprinting parameters. International Journal of Biological Macromolecules 222, pages 1453-1464.
Crossref
Wasmia Mohammed Dahan, Faruq Mohammad, Abdelrahman O. Ezzat, Ayman M. Atta, Hissah Hamad Al-Tilasi & Hamad A. Al-Lohedan. (2022) Influence of Amidation on the Release Profiles of Insulin Drug from Chitosan-Based Matrices. Coatings 12:4, pages 465.
Crossref
Leyla Saeednia, Li Yao & Ramazan Asmatulu. (2022) Chitosan and fullerene hybrid hydrogel for drug delivery system with enhanced antitumor cell effects. Materials Today: Proceedings 71, pages 130-137.
Crossref
Rogelio Rodríguez-Rodríguez, Hugo Espinosa-Andrews & Zaira Yunuen García-Carvajal. 2022. Functional Biomaterials. Functional Biomaterials 75 103 .
Marwa Hasanein Asfour, Sameh Hosam Abd El-Alim, Ghada Elsayed Ahmed Awad & Ahmed Alaa Kassem. (2021) Chitosan/β-glycerophosphate in situ forming thermo-sensitive hydrogel for improved ocular delivery of moxifloxacin hydrochloride. European Journal of Pharmaceutical Sciences 167, pages 106041.
Crossref
Sarah I. Othman, Asma M. Alturki, Gasem Mohammad Abu-Taweel, Naif Ghazi Altoom, Ahmed A. Allam & Rehab Abdelmonem. (2021) Chitosan for biomedical applications, promising antidiabetic drug delivery system, and new diabetes mellitus treatment based on stem cell. International Journal of Biological Macromolecules 190, pages 417-432.
Crossref
M. Isabel Rial-Hermida, Ana Rey-Rico, Barbara Blanco-Fernandez, Natalia Carballo-Pedrares, Eimear M. Byrne & João F. Mano. (2021) Recent Progress on Polysaccharide-Based Hydrogels for Controlled Delivery of Therapeutic Biomolecules. ACS Biomaterials Science & Engineering 7:9, pages 4102-4127.
Crossref
Somayeh Taymouri, Samaneh Amirkhani & Mina Mirian. (2021) Fabrication and characterization of injectable thermosensitive hydrogel containing dipyridamole loaded polycaprolactone nanoparticles for bone tissue engineering. Journal of Drug Delivery Science and Technology 64, pages 102659.
Crossref
M. I. Rial-Hermida, A. Rey-Rico, N. Carballo-Pedrares & J. F. Mano. 2021. Soft Matter for Biomedical Applications. Soft Matter for Biomedical Applications 518 541 .
Pouria Rahmanian-Devin, Vafa Baradaran Rahimi & Vahid Reza Askari. (2021) Thermosensitive Chitosan-β-Glycerophosphate Hydrogels as Targeted Drug Delivery Systems: An Overview on Preparation and Their Applications. Advances in Pharmacological and Pharmaceutical Sciences 2021, pages 1-17.
Crossref
Hina Shoukat, Khuda Buksh, Sobia Noreen, Fahad Pervaiz & Irsah Maqbool. (2021) Hydrogels as potential drug-delivery systems: network design and applications. Therapeutic Delivery 12:5, pages 375-396.
Crossref
Robin Augustine, Hashim Alhussain, Alap Ali Zahid, Syed Raza Ur Rehman, Rashid Ahmed & Anwarul Hasan. 2021. Nano Hydrogels. Nano Hydrogels 21 57 .
Sanjib Sarkar, Dibyendu Das, Prachurjya Dutta, Jatin Kalita, Sawlang Borsingh Wann & Prasenjit Manna. (2020) Chitosan: A promising therapeutic agent and effective drug delivery system in managing diabetes mellitus. Carbohydrate Polymers 247, pages 116594.
Crossref
Francivandi Coelho Barbosa, Milena Costa da Silva, Henrique Nunes da Silva, Danyllo Albuquerque, Allyson Antônio Ribeiro Gomes, Suédina Maria de Lima Silva & Marcus Vinícius Lia Fook. (2020) Progress in the Development of Chitosan Based Insulin Delivery Systems: A Systematic Literature Review. Polymers 12:11, pages 2499.
Crossref
Roxana Popescu, Mihaela Violeta Ghica, Cristina-Elena Dinu-Pîrvu, Valentina Anuța, Dumitru Lupuliasa & Lăcrămioara Popa. (2020) New Opportunity to Formulate Intranasal Vaccines and Drug Delivery Systems Based on Chitosan. International Journal of Molecular Sciences 21:14, pages 5016.
Crossref
Somayeh Taymouri, Mohsen Minaiyan, Farnaz Ebrahimi & Naser Tavakoli. (2020) In‐vitro and in‐vivo evaluation of chitosan‐based thermosensitive gel containing lorazepam NLCs for the treatment of status epilepticus. IET Nanobiotechnology 14:2, pages 148-154.
Crossref
Elham Khodaverdi, Khadijeh Delroba, Fatemeh Mohammadpour, Bahman Khameneh, Sayyed A. Sajadi Tabassi, Mohsen Tafaghodi, Hossein Kamali & Farzin Hadizadeh. (2020) In-vitro Release Evaluation of Growth Hormone from an Injectable In-Situ Forming Gel Using PCL-PEG-PCL Thermosensitive Triblock. Current Drug Delivery 17:2, pages 174-183.
Crossref
Balakrishnan Abinaya, Tandiakkal Prakash Prasith, Badrinath Ashwin, Syamala Viji Chandran & Nagarajan Selvamurugan. (2019) Chitosan in Surface Modification for Bone Tissue Engineering Applications. Biotechnology Journal 14:12, pages 1900171.
Crossref
Haile Fentahun Darge, Abegaz Tizazu Andrgie, Hsieh-Chih Tsai & Juin-Yih Lai. (2019) Polysaccharide and polypeptide based injectable thermo-sensitive hydrogels for local biomedical applications. International Journal of Biological Macromolecules 133, pages 545-563.
Crossref
Sarah Graham, Paula Facal Marina & Anton Blencowe. (2019) Thermoresponsive polysaccharides and their thermoreversible physical hydrogel networks. Carbohydrate Polymers 207, pages 143-159.
Crossref
Leyla Saeednia, Li Yao, Kim Cluff & Ramazan Asmatulu. (2019) Sustained Releasing of Methotrexate from Injectable and Thermosensitive Chitosan–Carbon Nanotube Hybrid Hydrogels Effectively Controls Tumor Cell Growth. ACS Omega 4:2, pages 4040-4048.
Crossref
Andjelka Račić, Bojan Čalija, Jela Milić, Nikola Milašinović & Danina Krajišnik. (2019) Development of polysaccharide-based mucoadhesive ophthalmic lubricating vehicles: The effect of different polymers on physicochemical properties and functionality. Journal of Drug Delivery Science and Technology 49, pages 50-57.
Crossref
Xian Jun Loh, Pei Lin Chee & Cally Owh. (2018) Biodegradable Thermogelling Polymers. Small Methods, pages 1800313.
Crossref
Hong Kit Lim, David James Young & Xian Jun Loh. 2018. Biodegradable Thermogels. Biodegradable Thermogels 76 86 .
Xiaoling Li, Bingwen Zou, Na Zhao, Chao Wang, Ying Du, Lan Mei, Yuelong Wang, Shangzhi Ma, Xing Tian, Jun He, Aiping Tong, Liangxue Zhou, Bo Han & Gang Guo. (2018) Potent Anti-adhesion Barrier Combined Biodegradable Hydrogel with Multifunctional Turkish Galls Extract. ACS Applied Materials & Interfaces 10:29, pages 24469-24479.
Crossref
Yuanhui Song, Nobuhiro Nagai, Saaya Saijo, Hirokazu Kaji, Matsuhiko Nishizawa & Toshiaki Abe. (2018) In situ formation of injectable chitosan-gelatin hydrogels through double crosslinking for sustained intraocular drug delivery. Materials Science and Engineering: C 88, pages 1-12.
Crossref
Heidrun Steinle, Tudor-Mihai Ionescu, Selina Schenk, Sonia Golombek, Silju-John Kunnakattu, Melek Tutku Özbek, Christian Schlensak, Hans Peter Wendel & Meltem Avci-Adali. (2018) Incorporation of Synthetic mRNA in Injectable Chitosan-Alginate Hybrid Hydrogels for Local and Sustained Expression of Exogenous Proteins in Cells. International Journal of Molecular Sciences 19:5, pages 1313.
Crossref
Yousef Pakzad & Fariba Ganji. (2015) Thermosensitive hydrogel for periodontal application: in vitro drug release, antibacterial activity and toxicity evaluation . Journal of Biomaterials Applications 30:7, pages 919-929.
Crossref
Emilia Szymańska, Katarzyna Winnicka, Piotr Wieczorek, Paweł Sacha & Elżbieta Tryniszewska. (2014) Influence of Unmodified and β-Glycerophosphate Cross-Linked Chitosan on Anti-Candida Activity of Clotrimazole in Semi-Solid Delivery Systems. International Journal of Molecular Sciences 15:10, pages 17765-17777.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.