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Journal of Receptors and Signal Transduction Volume 34, 2014 - Issue 4
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Research Article

p38 Mitogen-activated protein kinase accelerates emphysema in mouse model of chronic obstructive pulmonary disease

Hiroyuki AmanoDepartment of Biochemistry and Molecular Pharmacology;Department of Respirology, Graduate School of Medicine, Chiba University ChibaJapan
,
Kazuya MurataLife Science Center, Tsukuba Advanced Research Alliance, Graduate School of Life and Environmental Sciences, University of Tsukuba Tennoudai, IbarakiJapan
,
Hirofumi MatsunagaDepartment of Biochemistry and Molecular Pharmacology;Pharmaceuticals Research Laboratory, Ube Industries, Ltd. UbeJapan
,
Kensuke TanakaDepartment of Biochemistry and Molecular Pharmacology;Department of Respirology, Graduate School of Medicine, Chiba University ChibaJapan
,
Kento YoshiokaDepartment of Biochemistry and Molecular Pharmacology
,
Takeshi KobayashiDepartment of Biochemistry and Molecular Pharmacology;Department of Respirology, Graduate School of Medicine, Chiba University ChibaJapan
,
Junji IshidaLife Science Center, Tsukuba Advanced Research Alliance, Graduate School of Life and Environmental Sciences, University of Tsukuba Tennoudai, IbarakiJapan
,
Akiyoshi FukamizuLife Science Center, Tsukuba Advanced Research Alliance, Graduate School of Life and Environmental Sciences, University of Tsukuba Tennoudai, IbarakiJapan
,
Fumihiro SugiyamaLaboratory Animal Resource Center, University of Tsukuba Tennoudai, IbarakiJapan
,
Tatsuhiko SudoChemical Biology Core Facility and Antibiotics Laboratory, RIKEN Advanced Science Institute Wako, SaitamaJapan
,
Sadao KimuraDepartment of Biochemistry and Molecular Pharmacology
,
Koichiro TatsumiDepartment of Respirology, Graduate School of Medicine, Chiba University ChibaJapan
&
Yoshitoshi KasuyaDepartment of Biochemistry and Molecular PharmacologyCorrespondence[email protected]
 show all
Pages 299-306 | Received 23 Nov 2013, Accepted 17 Feb 2014, Published online: 05 Mar 2014

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Yongan Wang, Na Li, Qiuyi Li, Zirui Liu, Yalan Li, Jingwei Kong, Ruijuan Dong, Dongyu Ge, Jie Li & Guiying Peng. (2021) Xuanbai Chengqi Decoction Ameliorates Pulmonary Inflammation via Reshaping Gut Microbiota and Rectifying Th17/Treg Imbalance in a Murine Model of Chronic Obstructive Pulmonary Disease. International Journal of Chronic Obstructive Pulmonary Disease 16, pages 3317-3335.
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Articles from other publishers (10)

Ali Ahmadi, Sajjad Ahrari, Jafar Salimian, Zahra Salehi, Mehrdad Karimi, Alireza Emamvirdizadeh, Sadegh Azimzadeh Jamalkandi & Mostafa Ghanei. (2023) p38 MAPK signaling in chronic obstructive pulmonary disease pathogenesis and inhibitor therapeutics. Cell Communication and Signaling 21:1.
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Melissa Rivas, Gayatri Gupta, Louis Costanzo, Huma Ahmed, Anne E. Wyman & Patrick Geraghty. (2022) Senescence: Pathogenic Driver in Chronic Obstructive Pulmonary Disease. Medicina 58:6, pages 817.
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Jeremy C. Burton, William Antoniades, Jennifer Okalova, Morgan M. Roos & Neil J. Grimsey. (2021) Atypical p38 Signaling, Activation, and Implications for Disease. International Journal of Molecular Sciences 22:8, pages 4183.
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Hiroshi Maruoka, Ken-ichi Tanaka, Masaaki Takayanagi & Masashi Zenda. (2021) Effects of neuromuscular electrical stimulation on pulmonary alveola and cytokines in chronic obstructive pulmonary disease (COPD) and skeletal muscle atrophy model mice. Journal of Physical Therapy Science 33:1, pages 1-8.
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Shuichi Matsuda, Jun-Dal Kim, Fumihiro Sugiyama, Yuji Matsuo, Junji Ishida, Kazuya Murata, Kanako Nakamura, Kana Namiki, Tatsuhiko Sudo, Tomoyuki Kuwaki, Masahiko Hatano, Koichiro Tatsumi, Akiyoshi Fukamizu & Yoshitoshi Kasuya. (2020) Transcriptomic Evaluation of Pulmonary Fibrosis-Related Genes: Utilization of Transgenic Mice with Modifying p38 Signal in the Lungs. International Journal of Molecular Sciences 21:18, pages 6746.
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Cheng Yang, Li Li, Junhua Guo, Weiqiang Zhang, Wenbiao Zhu, Xinhui Rao & Wenjie Huang. (2017) Up-regulation of Pim-3 in Chronic Obstructive Pulmonary Disease (COPD) patients and its potential therapeutic role in COPD rat modeling. Pathology - Research and Practice 213:4, pages 322-326.
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Jae-Won Lee, Hyun Ah Park, Ok-Kyoung Kwon, Yin-Gi Jang, Ju Yeong Kim, Bo Kyung Choi, Hee Jae Lee, Sangwoo Lee, Jin-Hyub Paik, Sei-Ryang Oh, Kyung-Seop Ahn & Hyun-Jun Lee. (2016) Asiatic acid inhibits pulmonary inflammation induced by cigarette smoke. International Immunopharmacology 39, pages 208-217.
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Jalaj Gupta & Angel R. Nebreda. (2015) Roles of p38α mitogen‐activated protein kinase in mouse models of inflammatory diseases and cancer. The FEBS Journal 282:10, pages 1841-1857.
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Yoshitoshi Kasuya. (2015) Trends in functions and inhibitors of p38. Folia Pharmacologica Japonica 145:1, pages 21-26.
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Katie E. Baker, Sara J. Bonvini, Chantal Donovan, Rachel E. Foong, Bing Han, Aruni Jha, Yasin Shaifta, Marieke Smit, Jill R. Johnson & Lyn M. Moir. (2014) Novel drug targets for asthma and COPD: Lessons learned from in vitro and in vivo models. Pulmonary Pharmacology & Therapeutics 29:2, pages 181-198.
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