Advanced search
Publication Cover
Journal of Receptors and Signal Transduction Volume 35, 2015 - Issue 4
Submit an article Journal homepage
330
Views
22
CrossRef citations to date
0
Altmetric
Research Article

The small-molecule inhibitor selectivity between IKKα and IKKβ kinases in NF-κB signaling pathway

Feifei TianState Key Laboratory of Trauma, Burns and Combined Injury, Research Institute of Surgery, Daping Hospital, Third Military Medical University, Chongqing, China, ;School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, China, and
,
Peng ZhouCenter of Bioinformatics (COBI), School of Life Science and Technology, University of Electronic Science and Technology of China (UESTC), Chengdu, China
,
Wenyuan KangSchool of Life Science and Engineering, Southwest Jiaotong University, Chengdu, China, and
,
Li LuoState Key Laboratory of Trauma, Burns and Combined Injury, Research Institute of Surgery, Daping Hospital, Third Military Medical University, Chongqing, China,
,
Xia FanState Key Laboratory of Trauma, Burns and Combined Injury, Research Institute of Surgery, Daping Hospital, Third Military Medical University, Chongqing, China,
,
Jun YanState Key Laboratory of Trauma, Burns and Combined Injury, Research Institute of Surgery, Daping Hospital, Third Military Medical University, Chongqing, China,
&
Huaping LiangState Key Laboratory of Trauma, Burns and Combined Injury, Research Institute of Surgery, Daping Hospital, Third Military Medical University, Chongqing, China, Correspondence[email protected] [email protected]
 show all
Pages 307-318 | Received 09 Sep 2014, Accepted 22 Oct 2014, Published online: 11 Nov 2014

Citations (22)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

L. Zhu, Y. Yang & X. Lu. (2016) The selectivity and promiscuity of brain-neuroregenerative inhibitors between ROCK1 and ROCK2 isoforms: An integration of SB-QSSR modelling, QM/MM analysis and in vitro kinase assay. SAR and QSAR in Environmental Research 27:1, pages 47-65.
Read now

Articles from other publishers (21)

Xiaofei Shen, Hongqing Chen, Hai Zhang, Liuling Luo, Tian Wen, Lu Liu, Qiongying Hu & Lun Wang. (2023) A natural sesquiterpene lactone isolinderalactone attenuates lipopolysaccharide-induced inflammatory response and acute lung injury through inhibition of NF-κB pathway and activation Nrf2 pathway in macrophages. International Immunopharmacology 124, pages 110965.
Crossref
Di Wang, Huan Hu, Huan Ding, Han Zhao, Feifei Tian & Qingjia Chi. (2023) Elevated expression of TNFRSF4 impacts immune cell infiltration and gene mutation in hepatocellular carcinoma. Cancer Biomarkers 36:2, pages 147-159.
Crossref
FEIFEI TIAN, HUAN HU, DI WANG, HUAN DING, QINGJIA CHI, HUAPING LIANG & WENLI ZENG. (2022) Immune-related DNA methylation signature associated with APLN expression predicts prognostic of hepatocellular carcinoma. BIOCELL 46:10, pages 2291-2301.
Crossref
鑫 邹. (2022) OPN Involved in the Occurrence of Many Diseases through NF-ΚB Signaling Pathway. Advances in Clinical Medicine 12:07, pages 6601-6606.
Crossref
Waranya Neimkhum, Songyot Anuchapreeda, Wei-Chao Lin, Shang-Chian Lue, Kuan-Han Lee & Wantida Chaiyana. (2021) Effects of Carissa carandas Linn. Fruit, Pulp, Leaf, and Seed on Oxidation, Inflammation, Tyrosinase, Matrix Metalloproteinase, Elastase, and Hyaluronidase Inhibition. Antioxidants 10:9, pages 1345.
Crossref
Xueqian Zuo, Haibo Zhao & Dan Li. (2021) Systematic inhibitor selectivity between PARP1 and PARP2 enzymes: Molecular implications for ovarian cancer personalized therapy. Journal of Molecular Recognition 34:7.
Crossref
Huan Ding, Huan Hu, Feifei Tian & Huaping Liang. (2021) A dual immune signature of CD8+ T cells and MMP9 improves the survival of patients with hepatocellular carcinoma. Bioscience Reports 41:3.
Crossref
Laijun Song, Chunyu Zhu, Wenxin Zheng, Dan Lu, Hong Jiao, Rongbing Zhao & Zhonglei Bao. (2020) Computational systematic selectivity of the Fasalog inhibitors between ROCK-I and ROCK-II kinase isoforms in Alzheimer’s disease. Computational Biology and Chemistry 87, pages 107314.
Crossref
Robert Hartmann & Rodrigo Serna-Guerrero. (2020) A Study on the Electric Surface Potential and Hydrophobicity of Quartz Particles in the Presence of Hexyl Amine Cellulose Nanocrystals and Their Correlation to Flotation. Frontiers in Materials 7.
Crossref
Qingjia Chi, Zichang Yang, Kang Xu, Chunli Wang & Huaping Liang. (2020) DNA Nanostructure as an Efficient Drug Delivery Platform for Immunotherapy. Frontiers in Pharmacology 10.
Crossref
Raju Dash, Md. Arifuzzaman, Sarmistha Mitra, Md. Abdul Hannan, Nurul Absar & S.M. Zahid Hosen. (2019) Unveiling the Structural Insights into the Selective Inhibition of Protein Kinase D1. Current Pharmaceutical Design 25:10, pages 1059-1074.
Crossref
Min Han & Dongdong Sun. (2019) Rational creation and systematic analysis of cervical cancer kinase–inhibitor binding profile. Journal of Computer-Aided Molecular Design 33:7, pages 689-698.
Crossref
Elwira Chrobak, Monika Kadela-Tomanek, Ewa Bębenek, Krzysztof Marciniec, Joanna Wietrzyk, Justyna Trynda, Bartosz Pawełczak, Joachim Kusz, Janusz Kasperczyk, Ewa Chodurek, Piotr Paduszyński & Stanisław Boryczka. (2019) New phosphate derivatives of betulin as anticancer agents: Synthesis, crystal structure, and molecular docking study. Bioorganic Chemistry 87, pages 613-628.
Crossref
Meinrad Drexel, Johannes Kirchmair & Sandra Santos-Sierra. (2019) INH14, a Small-Molecule Urea Derivative, Inhibits the IKKα/β-Dependent TLR Inflammatory Response. ChemBioChem 20:5, pages 710-717.
Crossref
Narumi Hirata, Ryota Ichimaru, Tsukasa Tominari, Chiho Matsumoto, Kenta Watanabe, Keita Taniguchi, Michiko Hirata, Sihui Ma, Katsuhiko Suzuki, Florian Grundler, Chisato Miyaura & Masaki Inada. (2019) Beta-Cryptoxanthin Inhibits Lipopolysaccharide-Induced Osteoclast Differentiation and Bone Resorption via the Suppression of Inhibitor of NF-κB Kinase Activity. Nutrients 11:2, pages 368.
Crossref
Mirza S. Baig, Anjali Roy, Uzma Saqib, Sajjan Rajpoot, Mansi Srivastava, Adnan Naim, Dongfang Liu, Rohit Saluja, Syed M. Faisal, Qiuwei Pan, Kati Turkowski, Gajanan N. Darwhekar & Rajkumar Savai. (2018) Repurposing Thioridazine (TDZ) as an anti-inflammatory agent. Scientific Reports 8:1.
Crossref
Xiaohua Zhu, Qiugen Li, Guozhu Hu, Jun Wang, Qinghua Hu, Zhiqiang Liu, Gang Wu & Ying Zhong. (2018) BMS‑345541 inhibits airway inflammation and epithelial‑mesenchymal transition in airway remodeling of asthmatic mice. International Journal of Molecular Medicine.
Crossref
Serkan I. Göktuna, Michaela A. Diamanti & Tieu Lan Chau. (2018) IKK s and tumor cell plasticity . The FEBS Journal 285:12, pages 2161-2181.
Crossref
Xi Ding, Xingcai Liu & Lixia Zhu. (2017) Quantitative structure-selectivity relationship (QSSR)-based molecular insight into the cross-reactivity and specificity of chemotherapeutic inhibitors between PI3K α and PI3K β . Journal of Chemometrics 31:12, pages e2927.
Crossref
J.K. Durand & A.S. Baldwin. 2017. Chromatin Proteins and Transcription Factors as Therapeutic Targets. Chromatin Proteins and Transcription Factors as Therapeutic Targets 77 115 .
Anastasia V Rulina, Frédérique Mittler, Patricia Obeid, Sophie Gerbaud, Laurent Guyon, Eric Sulpice, Frédérique Kermarrec, Nicole Assard, Monika E Dolega, Xavier Gidrol & Maxim Y Balakirev. (2016) Distinct outcomes of CRL–Nedd8 pathway inhibition reveal cancer cell plasticity. Cell Death & Disease 7:12, pages e2505-e2505.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.