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Journal of Receptors and Signal Transduction Volume 15, 1995 - Issue 1-4
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Research Article

Growth Hormone Releasing Hexapeptide (GHRP-6) Activates the Inositol (1,4,5)-Trisphosphate/Diacylglycerol Pathway in Rat Anterior Pituitary Cells

Soren E. Mau Division of Endocrinology and Metabolism, Department of Physiology, The Panum Institute 12.2, University of Copenhagen, Blegdamsvej 3C, DK-2200, Copenhagen N, Denmark
,
Michael R. Witt Research Institute of Biological Psychiatry, Sct. Hans Hospital, Roskilde, Denmark
,
Ole J. Bjerrum Bioscience, Novo Nordisk A/S, Bagsærd, Denmark
,
Torben Særmark Dept. of Physical Chemistry, University of Technical Sciences, Lyngby, Denmark
&
Hans Vilhardt Division of Endocrinology and Metabolism, Department of Physiology, The Panum Institute 12.2, University of Copenhagen, Blegdamsvej 3C, DK-2200, Copenhagen N, Denmark
Pages 311-323 | Published online: 26 Sep 2008

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Amândio Rocha-Sousa, Tiago Henriques-Coelho & Adelino F Leite-Moreira. (2007) Potential role of the growth hormone secretagogues in clinical practice. Expert Opinion on Therapeutic Patents 17:8, pages 909-926.
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Johanna Wagner, Franca Vulinović, Anne Grünewald, Marcus M. Unger, Jens C. Möller, Christine Klein, Patrick P. Michel, Vincent Ries, Wolfgang H. Oertel & Daniel Alvarez-Fischer. (2017) Acylated and unacylated ghrelin confer neuroprotection to mesencephalic neurons. Neuroscience 365, pages 137-145.
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Cyril Y. Bowers, G. A. Reynolds & Johannes D. Veldhuis. 2012. Ghrelin in Health and Disease. Ghrelin in Health and Disease 1 35 .
Naoki Hattori. (2009) Expression, regulation and biological actions of growth hormone (GH) and ghrelin in the immune system. Growth Hormone & IGF Research 19:3, pages 187-197.
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Delphine Mousseaux, Lionel Le Gallic, Joanne Ryan, Catherine Oiry, Didier Gagne, Jean-Alain Fehrentz, Jean-Claude Galleyrand & Jean Martinez. (2006) Regulation of ERK1/2 activity by ghrelin-activated growth hormone secretagogue receptor 1A involves a PLC/PKC ɛ pathway . British Journal of Pharmacology 148:3, pages 350-365.
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Chi-Bun Chan, Po-Ki Leung, Helen Wise & Christopher H.K. Cheng. (2004) Signal transduction mechanism of the seabream growth hormone secretagogue receptor. FEBS Letters 577:1-2, pages 147-153.
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Elena Bresciani, Ralf Nass, Antonio Torsello, Bruce Gaylinn, Roberta Avallone, Vittorio Locatelli, Michael O. Thorner & Eugenio E. Müller. (2004) Hexarelin Modulates the Expression of Growth Hormone Secretagogue Receptor Type 1a mRNA at Hypothalamic and Pituitary Sites. Neuroendocrinology 80:1, pages 52-59.
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F. Gracia-Navarro, J.P. Castaño, M.M. Malagon, A. Sánchez-Hormigo, R.M. Luque, G.J. Hickey, J.R. Peinado, E. Delgado & A.J. Martı́nez-Fuentes. (2002) Research progress in the stimulatory inputs regulating growth hormone (GH) secretion. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 132:1, pages 141-150.
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Arthur A. Patchett, Roy G. Smith & Matthew J. Wyvratt. 2002. Integration of Pharmaceutical Discovery and Development. Integration of Pharmaceutical Discovery and Development 525 554 .
Angel GarcíaClara V. AlvarezRoy G. Smith & Carlos Diéguez. (2001) Regulation of PIT-1 Expression By Ghrelin and GHRP-6 Through the GH Secretagogue Receptor. Molecular Endocrinology 15:9, pages 1484-1495.
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Kyongsong Kim, Keiko Arai, Naoko Sanno, R. Yoshiyuki Osamura, Akira Teramoto & Tamotsu Shibasaki. (2002) Ghrelin and growth hormone (GH) secretagogue receptor (GHSR) mRNA expression in human pituitary adenomas. Clinical Endocrinology 54:6, pages 759-768.
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C.D McMahon, R.P Radcliff, K.J Lookingland & H.A Tucker. (2001) Neuroregulation of growth hormone secretion in domestic animals. Domestic Animal Endocrinology 20:2, pages 65-87.
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H. Tamura, J. Kamegai, H. Sugihara, R. D. Kineman, L. A. Frohman & I. Wakabayashi. (2001) Glucocorticoids Regulate Pituitary Growth Hormone Secretagogue Receptor Gene Expression. Journal of Neuroendocrinology 12:6, pages 481-485.
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Cyril Y. Bowers. 2011. Comprehensive Physiology. Comprehensive Physiology 267 297 .
Audrey Petit, Catherine Bleicher & Benoît T Lussier. (1999) Intracellular calcium stores are involved in growth hormone-releasing hormone signal transduction in rat somatotrophs. Canadian Journal of Physiology and Pharmacology 77:7, pages 520-528.
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Andrea GiustinaJohannes D. Veldhuis. (1998) Pathophysiology of the Neuroregulation of Growth Hormone Secretion in Experimental Animals and the Human*. Endocrine Reviews 19:6, pages 717-797.
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Roy G. Smith, Lex H. T. Van der Ploeg, Andrew D. Howard, Scott D. Feighner, Kang Cheng, Gerard J. Hickey, Matthew J. WyvrattJr.Jr., Mike H. Fisher, Ravi P. Nargund & Arthur A. Patchett. (1997) Peptidomimetic Regulation of Growth Hormone Secretion. Endocrine Reviews 18:5, pages 621-645.
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Roy G. Smith, Kang Cheng, Sheng-Shung Pong, Reid Leonard, Charles J. Cohen, Joseph P. Arena, Gerard J. Hickey, Ching H. Chang, Tom Jacks, Jennifer Drisko, Iain C. A. F. Robinson, Suzanne L. Dickson & Gareth Leng. 1996. Growth Hormone Secretagogues. Growth Hormone Secretagogues 147 163 .

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