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Research Article

Statistical optimization of insulin-loaded Pluronic F-127 gels for buccal delivery of basal insulin

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Pages 363-374 | Received 20 Oct 2010, Accepted 09 Nov 2010, Published online: 10 Jan 2011

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Read on this site (7)

Anuja Paprikar, Ankit Soni, Neeraj Kaushal & Senshang Lin. (2021) Sublingual insulin administration: application of hydroxypropyl beta-cyclodextrin and poloxamer188 as permeation enhancers. Pharmaceutical Development and Technology 26:2, pages 233-242.
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Safy Hadiya, Radwa Radwan, Menna Zakaria, Tahra El-Sherif, Mostafa A. Hamad & Mahmoud Elsabahy. (2021) Nanoparticles integrating natural and synthetic polymers for in vivo insulin delivery. Pharmaceutical Development and Technology 26:1, pages 30-40.
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A. Jaipal, M. M Pandey, S. Y. Charde, N. Sadhu, A. Srinivas & R. G. Prasad. (2016) Controlled release effervescent buccal discs of buspirone hydrochloride: in vitro and in vivo evaluation studies. Drug Delivery 23:2, pages 452-458.
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Anna-Lena Kjøniksen, Maria Teresa Calejo, Kaizheng Zhu, Bo Nyström & Sverre Arne Sande. (2015) Stabilization of Pluronic Gels by Hydrophobically Modified Hydroxyethylcellulose. International Journal of Polymeric Materials and Polymeric Biomaterials 64:2, pages 76-83.
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Muhammad Sajid Hamid Akash, Kanwal Rehman & Shuqing Chen. (2015) Natural and Synthetic Polymers as Drug Carriers for Delivery of Therapeutic Proteins. Polymer Reviews 55:3, pages 371-406.
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Muhammad Sajid Hamid Akash, Kanwal Rehman & Shuqing Chen. (2014) Pluronic F127-Based Thermosensitive Gels for Delivery of Therapeutic Proteins and Peptides. Polymer Reviews 54:4, pages 573-597.
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Muhammad Sajid Hamid Akash, Kanwal Rehman, Hongying Sun & Shuqing Chen. (2014) Assessment of release kinetics, stability and polymer interaction of poloxamer 407-based thermosensitive gel of interleukin-1 receptor antagonist. Pharmaceutical Development and Technology 19:3, pages 278-284.
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Articles from other publishers (12)

Amani Elsayed, Mayyas Al-Remawi, Nisrein Jaber & Khalid M. Abu-Salah. (2023) Advances in buccal and oral delivery of insulin. International Journal of Pharmaceutics 633, pages 122623.
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Kwadwo Mfoafo, Young Kwon, Yadollah Omidi & Hossein Omidian. (2022) Contemporary applications of thermogelling PEO-PPO-PEO triblock copolymers. Journal of Drug Delivery Science and Technology 70, pages 103182.
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Sabine Szunerits, Sorin Melinte, Alexandre Barras, Quentin Pagneux, Anna Voronova, Amar Abderrahmani & Rabah Boukherroub. (2021) The impact of chemical engineering and technological advances on managing diabetes: present and future concepts. Chemical Society Reviews 50:3, pages 2102-2146.
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Muhammad H. Sultan, Wael A. Mahdi & Young M. Kwon. (2020) Insulin Release from NPH Insulin-Loaded Pluronic® F127 Hydrogel in the Presence of Simulated Tissue Enzyme Activity. Processes 8:10, pages 1320.
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Davide Zanon, Chiara Volpato, Riccardo Addobbati, Stefano Loiacono, Alessandra Maestro, Egidio Barbi, Natalia Maximova, Maria Grazia Mamolo & Daniele Zampieri. (2019) Stability of a novel Lidocaine, Adrenaline and Tetracaine sterile thermosensitive gel: A ready-to-use formulation. European Journal of Pharmaceutical Sciences 136, pages 104962.
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Abdullah Ali, Marie Wahlgren, Lina Pedersen & Johan Engblom. (2018) Will a water gradient in oral mucosa affect transbuccal drug absorption?. Journal of Drug Delivery Science and Technology 48, pages 338-345.
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Amir Fakhari, Marta Corcoran & Alexander Schwarz. (2017) Thermogelling properties of purified poloxamer 407. Heliyon 3:8, pages e00390.
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Jason Li, Michael K. Chu, Brian Lu, Sako Mirzaie, Kuan Chen, Claudia R. Gordijo, Oliver Plettenburg, Adria Giacca & Xiao Yu Wu. (2017) Enhancing thermal stability of a highly concentrated insulin formulation with Pluronic F-127 for long-term use in microfabricated implantable devices. Drug Delivery and Translational Research 7:4, pages 529-543.
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Mohammed Sattar, Ossama M. Sayed & Majella E. Lane. (2014) Oral transmucosal drug delivery – Current status and future prospects. International Journal of Pharmaceutics 471:1-2, pages 498-506.
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Muhammad Sajid Hamid Akash, Kanwal Rehman & Shuqing Chen. (2013) IL-1Ra and its Delivery Strategies: Inserting the Association in Perspective. Pharmaceutical Research 30:11, pages 2951-2966.
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Muhammad Sajid Hamid Akash, Kanwal Rehman, Hongying Sun & Shuqing Chen. (2013) Sustained Delivery of IL-1Ra from PF127-Gel Reduces Hyperglycemia in Diabetic GK-Rats. PLoS ONE 8:2, pages e55925.
Crossref
Lutz Heinemann. (2013) Insulin Pens and New Ways of Insulin Delivery. Diabetes Technology & Therapeutics 15:S1, pages S-48-S-59.
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