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Research Article

Development and characterization of a lovastatin-loaded self-microemulsifying drug delivery system

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Pages 469-483 | Received 30 Jun 2009, Accepted 25 Aug 2009, Published online: 01 Oct 2009

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Read on this site (11)

Afzal Hussain, Sandeep Kumar Singh, Priya Ranjan Prasad Verma, Neeru Singh & Farhan Jalees Ahmad. (2017) Experimental design-based optimization of lipid nanocarrier as delivery system against Mycobacterium species: in vitro and in vivo evaluation. Pharmaceutical Development and Technology 22:7, pages 910-927.
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Sarwar Beg, Premjeet Singh Sandhu, Rattandeep Singh Batra, Rajneet Kaur Khurana & Bhupinder Singh. (2015) QbD-based systematic development of novel optimized solid self-nanoemulsifying drug delivery systems (SNEDDS) of lovastatin with enhanced biopharmaceutical performance. Drug Delivery 22:6, pages 765-784.
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Neeru Singh, Saurabh Manaswita Verma, Sandeep Kumar Singh, Priya Ranjan Prasad Verma & Mohd. Neyaz Ahsan. (2015) Antibacterial activity of cationised and non-cationised placebo lipidic nanoemulsion using transmission electron microscopy. Journal of Experimental Nanoscience 10:4, pages 299-309.
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Samridhi Verma, Sandeep Kumar Singh, Priya Ranjan Prasad Verma & Mohd Neyaz Ahsan. (2014) Formulation by design of felodipine loaded liquid and solid self nanoemulsifying drug delivery systems using Box–Behnken design. Drug Development and Industrial Pharmacy 40:10, pages 1358-1370.
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Pattravee Niamprem, Soravoot Rujivipat & Waree Tiyaboonchai. (2014) Development and characterization of lutein-loaded SNEDDS for enhanced absorption in Caco-2 cells. Pharmaceutical Development and Technology 19:6, pages 735-742.
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Rini Saini, Sandeep Kumar Singh & Priya Ranjan Prasad Verma. (2014) Evaluation of carvedilol-loaded microsponges with nanometric pores using response surface methodology. Journal of Experimental Nanoscience 9:8, pages 831-850.
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Mohd Neyaz Ahsan, Priya Ranjan Prasad Verma, Sandeep Kumar Singh, Samridhi & Madhu Yashpal. (2014) Formulation of Rosuvastatin-Loaded Self-Nanoemulsifying Drug Delivery System Using Box-Behnken Design. Particulate Science and Technology 32:1, pages 46-60.
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Chandralekha Bhagat, Sandeep Kumar Singh, Priya Ranjan Prasad Verma, Neeru Singh, Samridhi Verma & Mohd Neyaz Ahsan. (2013) Crystalline and amorphous carvedilol-loaded nanoemulsions: formulation optimisation using response surface methodology. Journal of Experimental Nanoscience 8:7-8, pages 971-992.
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Sandeep Kumar Singh, Priya Ranjan Prasad Verma & Balkishen Razdan. (2011) Structural Transitions of Self-Nanoemulsifying Drug Delivery System of Glibenclamide, Carvedilol, and Lovastatin upon Progressive Aqueous Dilution. Journal of Dispersion Science and Technology 32:6, pages 771-777.
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Sridevi Gowripattapu, D. Sathis Kumar & S. Selvamuthukumar. (2023) Formulation and Statistical Evaluation of Tablets Containing Pitavastatin- Self Nano Emulsifying Drug Delivery Systems. Current Drug Delivery 20:4, pages 414-432.
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Teenu Sharma, Atul Jain, Ranjot Kaur, Sumant Saini, O P Katare & Bhupinder Singh. (2020) Supersaturated LFCS type III self-emulsifying delivery systems of sorafenib tosylate with improved biopharmaceutical performance: QbD-enabled development and evaluation. Drug Delivery and Translational Research 10:4, pages 839-861.
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Eleni Kontogiannidou, Thomas Meikopoulos, Helen Gika, Emmanuel Panteris, Ioannis S. Vizirianakis, Anette Müllertz & Dimitrios G. Fatouros. (2020) In Vitro Evaluation of Self-Nano-Emulsifying Drug Delivery Systems (SNEDDS) Containing Room Temperature Ionic Liquids (RTILs) for the Oral Delivery of Amphotericin B. Pharmaceutics 12:8, pages 699.
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Rania M. Hathout, AbdelKader A. Metwally, Timothy J. WoodmanJohn G. Hardy. (2020) Prediction of Drug Loading in the Gelatin Matrix Using Computational Methods. ACS Omega 5:3, pages 1549-1556.
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Ilham Kuncahyo, Syaiful Choiri, Achmad FudholiRonny Martien & Abdul Rohman. (2019) Assessment of Fractional Factorial Design for the Selection andScreening of Appropriate Components of a Self-nanoemulsifyingDrug Delivery System Formulation. Advanced Pharmaceutical Bulletin 9:4, pages 609-618.
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Afzal Hussain, Faiyaz Shakeel, Sandeep Kumar Singh, Ibrahim A. Alsarra, Abdul Faruk, Fars K. Alanazi & G.V. Peter Christoper. (2019) Solidified SNEDDS for the oral delivery of rifampicin: Evaluation, proof of concept, in vivo kinetics, and in silico GastroPlusTM simulation. International Journal of Pharmaceutics 566, pages 203-217.
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Mohd Neyaz Ahsan & Priya Ranjan Prasad Verma. (2017) Enhancement of in vitro dissolution and pharmacodynamic potential of olanzapine using solid SNEDDS. Journal of Pharmaceutical Investigation 48:3, pages 269-278.
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Arka Bhattacharjee, Samridhi Verma, Priya Ranjan Prasad Verma, Sandeep Kumar Singh & Arpan Chakraborty. (2017) Fabrication of liquid and solid self-double emulsifying drug delivery system of atenolol by response surface methodology. Journal of Drug Delivery Science and Technology 41, pages 45-57.
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Khalid M. El-Say, Tarek A. Ahmed, Osama A.A. Ahmed, Khaled M. Hosny & Fathy I. Abd-Allah. (2017) Self-Nanoemulsifying Lyophilized Tablets for Flash Oral Transmucosal Delivery of Vitamin K: Development and Clinical Evaluation. Journal of Pharmaceutical Sciences 106:9, pages 2447-2456.
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Mohd Neyaz Ahsan & Priya Ranjan Prasad Verma. (2016) Development, optimization and pharmacodynamic assessment of olanzapine based lipidic SNEDDS for proficient management of psychosis. Journal of Pharmaceutical Investigation 47:5, pages 395-411.
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Mai Khanfar & Suhair Al-Nimry. (2017) Stabilization and Amorphization of Lovastatin Using Different Types of Silica. AAPS PharmSciTech 18:6, pages 2358-2367.
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Md. Akhlaquer Rahman, Md. Mujahid, Arshad Hussain & Zeenat Iqbal. (2016) Development and pharmacokinetic evaluation of spray-dried self-nanoemulsifying drug delivery system of sertraline. Journal of Pharmaceutical Investigation 47:4, pages 325-333.
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Hasan Ali, Priya Ranjan Prasad Verma, Sunil Kumar Dubey, Jayachandran Venkatesan, Youngwan Seo, Se-Kwon Kim & Sandeep Kumar Singh. (2017) In vitro–in vivo and pharmacokinetic evaluation of solid lipid nanoparticles of furosemide using Gastroplus™. RSC Advances 7:53, pages 33314-33326.
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Hasan Ali & Sandeep Kumar Singh. (2016) Biological voyage of solid lipid nanoparticles: a proficient carrier in nanomedicine. Therapeutic Delivery 7:10, pages 691-709.
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Hea-Young Cho, Jun-Hyuk Kang, Lien Ngo, Phuong Tran & Yong-Bok Lee. (2016) Preparation and Evaluation of Solid-Self-Emulsifying Drug Delivery System Containing Paclitaxel for Lymphatic Delivery. Journal of Nanomaterials 2016, pages 1-14.
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Afzal Hussain, Sandeep Kumar Singh, Neeru Singh & Priya Ranjan Prasad Verma. (2016) In vitro–in vivo–in silico simulation studies of anti-tubercular drugs doped with a self nanoemulsifying drug delivery system. RSC Advances 6:95, pages 93147-93161.
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Samridhi Verma, Sandeep Kumar Singh & Priya Ranjan Prasad Verma. (2016) Solidified SNEDDS of loratadine: formulation using hydrophilic and hydrophobic grades of Aerosil®, pharmacokinetic evaluations and in vivo–in silico predictions using GastroPlus™. RSC Advances 6:4, pages 3099-3116.
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Wael Fagir, Rania M Hathout, Omaima A Sammour & Ahmed H ElShafeey. (2015) Self-microemulsifying systems of Finasteride with enhanced oral bioavailability: multivariate statistical evaluation, characterization, spray-drying and in vivo studies in human volunteers . Nanomedicine 10:22, pages 3373-3389.
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Amelia M. Avachat & Vijay G. Patel. (2015) Self nanoemulsifying drug delivery system of stabilized ellagic acid–phospholipid complex with improved dissolution and permeability. Saudi Pharmaceutical Journal 23:3, pages 276-289.
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Pankajkumar Yadav, Ekta Yadav, Amita Verma & Saima Amin. (2014) In vitro characterization and pharmacodynamic evaluation of furosemide loaded self nano emulsifying drug delivery systems (SNEDDS). Journal of Pharmaceutical Investigation 44:6, pages 443-453.
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Liu Guoqing, Zhou Huafeng, Zhang Jing, Yan Zemin, Duan Mingxing, Long Yingfang & Xia Qiang. (2014) Preparation and characterisation of a soy lecithin‐based self‐microemulsifying drug delivery system of resveratrol. Micro & Nano Letters 9:9, pages 561-565.
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Pankajkumar S. Yadav, Ekta Yadav, Amita Verma & Saima Amin. (2014) Development, Characterization, and Pharmacodynamic Evaluation of Hydrochlorothiazide Loaded Self-Nanoemulsifying Drug Delivery Systems. The Scientific World Journal 2014, pages 1-10.
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Kevin C. Garala, Jaydeep M. Patel, Anjali P. Dhingani & Abhay T. Dharamsi. (2013) Quality by design (QbD) approach for developing agglomerates containing racecadotril and loperamide hydrochloride by crystallo-co-agglomeration. Powder Technology 247, pages 128-146.
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Kevin C. Garala, Jaydeep M. Patel, Anjali P. Dhingani & Abhay T. Dharamsi. (2013) Preparation and evaluation of agglomerated crystals by crystallo-co-agglomeration: An integrated approach of principal component analysis and Box–Behnken experimental design. International Journal of Pharmaceutics 452:1-2, pages 135-156.
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Shantanu Bandyopadhyay, O.P. Katare & Bhupinder Singh. (2012) Optimized self nano-emulsifying systems of ezetimibe with enhanced bioavailability potential using long chain and medium chain triglycerides. Colloids and Surfaces B: Biointerfaces 100, pages 50-61.
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Md. Akhlaquer Rahman, Zeenat Iqbal & Arshad Hussain. (2012) Formulation optimization and in vitro characterization of sertraline loaded self-nanoemulsifying drug delivery system (SNEDDS) for oral administration. Journal of Pharmaceutical Investigation 42:4, pages 191-202.
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Rania M. Hathout & Timothy J. Woodman. (2012) Applications of NMR in the characterization of pharmaceutical microemulsions. Journal of Controlled Release 161:1, pages 62-72.
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Nitin Parmar, Neelam Singla, Saima Amin & Kanchan Kohli. (2011) Study of cosurfactant effect on nanoemulsifying area and development of lercanidipine loaded (SNEDDS) self nanoemulsifying drug delivery system. Colloids and Surfaces B: Biointerfaces 86:2, pages 327-338.
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