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Research Article

Control of drug release by incorporation of sorbitol or mannitol in microcrystalline-cellulose-based pellets prepared by extrusion-spheronization

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Pages 626-635 | Received 23 Jul 2009, Accepted 14 Oct 2009, Published online: 11 Feb 2010

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Read on this site (6)

Yu Xia, Chun-Yang Shi, Jian-Guo Fang & Wen-Qing Wang. (2018) Approaches to developing fast release pellets via wet extrusion-spheronization. Pharmaceutical Development and Technology 23:5, pages 432-441.
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Ihatanderson Alves-Silva, Ricardo N. Marreto, Guilherme M. Gelfuso, Lívia C. L. Sá-Barreto, Eliana M. Lima & Marcílio S. S. Cunha-Filho. (2017) Preparation of benznidazole pellets for immediate drug delivery using the extrusion spheronization technique. Drug Development and Industrial Pharmacy 43:5, pages 762-769.
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Gustavo H. C. Varca, Patricia S. Lopes & Humberto G. Ferraz. (2015) Development of papain containing pellets produced by extrusion–spheronization: an operational stage approach. Drug Development and Industrial Pharmacy 41:3, pages 430-435.
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Alvaro Goyanes & Ramón Martínez-Pacheco. (2015) New co-processed MCC-based excipient for fast release of low solubility drugs from pellets prepared by extrusion-spheronization. Drug Development and Industrial Pharmacy 41:3, pages 362-368.
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Alvaro Goyanes, Consuelo Souto & Ramón Martínez-Pacheco. (2013) Chitosan–kaolin coprecipitate as disintegrant in microcrystalline cellulose-based pellets elaborated by extrusion–spheronization. Pharmaceutical Development and Technology 18:1, pages 137-145.
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Alvaro Goyanes, Consuelo Souto & Ramón Martínez-Pacheco. (2011) A comparison of chitosan-silica and sodium starch glycolate as disintegrants for spheronized extruded microcrystalline cellulose pellets. Drug Development and Industrial Pharmacy 37:7, pages 825-831.
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Articles from other publishers (6)

Giovanni Falcone, Sonja Kuth, Aldo R. Boccaccini, Rita P. Aquino, Tiziana Esposito & Paola Russo. (2023) Application of Calcium Alginate Hydrogels in Semisolid Extrusion 3D Printed for the Production of Easy‐to‐Swallow Tablets. Advanced Engineering Materials 25:9.
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Idris M. El-Mahdi & Salma A. El-Shhibia. (2017) Effect of spheronizer plate design on the spheronization of ketoprofen. Future Journal of Pharmaceutical Sciences 3:2, pages 153-157.
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Alvaro Goyanes, Masanori Kobayashi, Ramón Martínez-Pacheco, Simon Gaisford & Abdul W. Basit. (2016) Fused-filament 3D printing of drug products: Microstructure analysis and drug release characteristics of PVA-based caplets. International Journal of Pharmaceutics 514:1, pages 290-295.
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Thanh Huong Hoang Thi, Siham Lhafidi, Simone Pinto Carneiro & Marie-Pierre Flament. (2015) Feasability of a new process to produce fast disintegrating pellets as novel multiparticulate dosage form for pediatric use. International Journal of Pharmaceutics 496:2, pages 842-849.
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Srimanta Sarkar, Bee Hwee Ang & Celine Valeria Liew. (2013) Influence of Starting Material Particle Size on Pellet Surface Roughness. AAPS PharmSciTech 15:1, pages 131-139.
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Alvaro Goyanes, Consuelo Souto & Ramón Martínez-Pacheco. (2011) Co-processed MCC-Eudragit® E excipients for extrusion–spheronization. European Journal of Pharmaceutics and Biopharmaceutics 79:3, pages 658-663.
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