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Pharmaceutical Development and Technology Volume 16, 2011 - Issue 2
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Research Article

Effect of gel composition and phonophoresis on the transdermal delivery of ibuprofen: In vitro and in vivo evaluation

Mahasen MeshaliMansoura University, Mansoura, Egypt
,
Hamdy Abdel-AleemMansoura University, Mansoura, Egypt
,
Farouk SakrMansoura University, Mansoura, Egypt
,
Sami NazzalUniversity of Louisiana at Monroe, Louisiana, Monroe, USA
&
Yasser El-MalahMansoura University, Mansoura, EgyptCorrespondence[email protected]
Pages 93-101 | Received 19 Sep 2009, Accepted 19 Nov 2009, Published online: 25 Jan 2010

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Ron Clijsen, Jean Pierre Baeyens, André Odilon Barel & Peter Clarys. (2015) In vivo determination of the diclofenac skin reservoir: comparison between passive, occlusive, and iontophoretic application. Drug Design, Development and Therapy 9, pages 835-840.
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Ivana Pantelic, Milica Lukic, Bojan Markovic, Rolf Daniels, Sonja Vesic, Gordana Vuleta & Snezana Savic. (2014) Effect of small changes in natural origin-based emulsion systems on hydrocortisone skin absorption and performance: a comparison of two in vivo methods. Pharmaceutical Development and Technology 19:1, pages 55-64.
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Ying-Zheng Zhao, Li-Na Du, Cui-Tao Lu, Yi-Guang Jin & Shu-Ping Ge. (2013) Potential and problems in ultrasound-responsive drug delivery systems. International Journal of Nanomedicine 8, pages 1621-1633.
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Articles from other publishers (13)

Francisco Javier Martin-Vega, David Lucena-Anton, Alejandro Galán-Mercant, Veronica Perez-Cabezas, Carlos Luque-Moreno, Maria Jesus Vinolo-Gil & Gloria Gonzalez-Medina. (2022) Phonophoresis through Nonsteroidal Anti-Inflammatory Drugs for Knee Osteoarthritis Treatment: Systematic Review and Meta-Analysis. Biomedicines 10:12, pages 3254.
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Zhiguo Li, Xuexun Fang & Dahai Yu. (2021) Transdermal Drug Delivery Systems and Their Use in Obesity Treatment. International Journal of Molecular Sciences 22:23, pages 12754.
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Caroline Bomfim Lemos da Cruz, Luis Fernando Sousa Filho, Diego Alves Lima, Joyce Izabel de Gois & Evaleide Diniz de Oliveira. (2021) Effect of Phonophoresis and Copaiba Oil on Oxidative Stress Biomarkers after Skeletal Muscle Injury in Rats. Ultrasound in Medicine & Biology 47:9, pages 2657-2663.
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S. TOLU, M. M. KÖSE, M. C. KORKMAZ, A. ÜŞEN & A. REZVANİ. (2021) Comparison of the Efficacy of Different Concentrations of Diclofenac Sodium Phonophoresis (1.16% vs 2.32%) in Patients with Knee Osteoarthritis: a Randomized Double-Blind Controlled Trial. Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca 88:2, pages 117-123.
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Jack Masterson, Brett Kluge, Aaron Burdette & George Lewis Sr. (2020) Sustained acoustic medicine; sonophoresis for nonsteroidal anti-inflammatory drug delivery in arthritis. Therapeutic Delivery 11:6, pages 363-372.
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Meng-qiu Xia, Chun-ling Tian, Liu Liu, Rong-feng Hu, Shuang-ying Gui & Xiao-qin Chu. (2020) Transdermal Administration of Ibuprofen-Loaded Gel: Preparation, Pharmacokinetic Profile, and Tissue Distribution. AAPS PharmSciTech 21:3.
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Saloni Daftardar, Rabin Neupane, Sai HS. Boddu, Jwala Renukuntla & Amit K. Tiwari. (2019) Advances in Ultrasound Mediated Transdermal Drug Delivery. Current Pharmaceutical Design 25:4, pages 413-423.
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Ilke Coskun Benlidayi, Neslihan Gokcen & Sibel Basaran. (2018) Comparative short-term effectiveness of ibuprofen gel and cream phonophoresis in patients with knee osteoarthritis. Rheumatology International 38:10, pages 1927-1932.
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Rachna Prasad & Veena Koul. 2018. Polymer Gels. Polymer Gels 343 375 .
José Juan Escobar-Chávez, Roberto Díaz-Torres, Clara Luisa Domínguez-Delgado, Isabel Marlen Rodríguez-Cruz, Raquel López-Arellano & Elvia Adriana Morales Hipólito. 2017. Percutaneous Penetration Enhancers Physical Methods in Penetration Enhancement. Percutaneous Penetration Enhancers Physical Methods in Penetration Enhancement 31 58 .
Mai Aldwaikat & Mohammed Alarjah. (2015) Investigating the sonophoresis effect on the permeation of diclofenac sodium using 3D skin equivalent. Ultrasonics Sonochemistry 22, pages 580-587.
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Aharon Azagury, Luai Khoury, Giora Enden & Joseph Kost. (2014) Ultrasound mediated transdermal drug delivery. Advanced Drug Delivery Reviews 72, pages 127-143.
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Wanwadee Luksurapan & Jariya Boonhong. (2013) Effects of Phonophoresis of Piroxicam and Ultrasound on Symptomatic Knee Osteoarthritis. Archives of Physical Medicine and Rehabilitation 94:2, pages 250-255.
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