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Research Article

Evaluation and modeling of the eutectic composition of various drug-polyethylene glycol solid dispersions

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Pages 201-211 | Received 30 Nov 2009, Accepted 18 Dec 2009, Published online: 09 Feb 2010

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Haiyan Li, Yonggang Tan, Lixia Yang, Lijun Gao, Tao Wang, Xi Yang & Dongqin Quan. (2015) Dissolution evaluation in vitro and bioavailability in vivo of self-microemulsifying drug delivery systems for pH-sensitive drug loratadine. Journal of Microencapsulation 32:2, pages 175-180.
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Parinda Srinarong, Hans de Waard, Henderik W Frijlink & Wouter LJ Hinrichs. (2011) Improved dissolution behavior of lipophilic drugs by solid dispersions: the production process as starting point for formulation considerations. Expert Opinion on Drug Delivery 8:9, pages 1121-1140.
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Krit Suknuntha, Nattakanwadee Khumpirapang, Vimon Tantishaiyakul & Siriporn Okonogi. (2023) Solubility and Physical Stability Enhancement of Loratadine by Preparation of Co-Amorphous Solid Dispersion with Chlorpheniramine and Polyvinylpyrrolidone. Pharmaceutics 15:11, pages 2558.
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Purnima N. Manghnani, Luke Schenck, Saif A. Khan & Patrick S. Doyle. (2023) Templated Reactive Crystallization of Active Pharmaceutical Ingredient in Hydrogel Microparticles Enabling Robust Drug Product Processing. Journal of Pharmaceutical Sciences 112:8, pages 2115-2123.
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Jie Zhang, Minshan Guo, Minqian Luo & Ting Cai. (2023) Advances in the development of amorphous solid dispersions: The role of polymeric carriers. Asian Journal of Pharmaceutical Sciences 18:4, pages 100834.
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Yong Zhang, Qiuli Yan, Yao Liu & Chunhui Hu. (2023) Study on the regulation mechanism of effective glass transition temperature on the crystallization of crystalline solid dispersion. Drug Delivery and Translational Research.
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Serena Bertoni, Beatrice Albertini & Nadia Passerini. (2023) Investigating the physicochemical properties of solid dispersions based on semicrystalline carriers: A case study with ketoprofen. International Journal of Pharmaceutics 632, pages 122576.
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A. V. Basko, T. N. Lebedeva, M. Yu. Yurov & K. V. Pochivalov. (2021) The Effect of Physical State of Thymol on the Duration of Its Release from the Mixture with a Semicrystalline Polymer: Thermodynamic Aspects and Kinetics of the Process. Polymer Science, Series A 64:1, pages 10-18.
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Nele-Johanna Hempel, Matthias M. Knopp, J. Axel Zeitler, Ragna Berthelsen & Korbinian Löbmann. (2021) Microwave-Induced in Situ Drug Amorphization Using a Mixture of Polyethylene Glycol and Polyvinylpyrrolidone. Journal of Pharmaceutical Sciences 110:9, pages 3221-3229.
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Xiaoning Shan, Adrian C. Williams & Vitaliy V. Khutoryanskiy. (2020) Polymer structure and property effects on solid dispersions with haloperidol: Poly(N-vinyl pyrrolidone) and poly(2-oxazolines) studies. International Journal of Pharmaceutics 590, pages 119884.
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Serena Bertoni, Beatrice Albertini & Nadia Passerini. (2020) Different BCS Class II Drug-Gelucire Solid Dispersions Prepared by Spray Congealing: Evaluation of Solid State Properties and In Vitro Performances. Pharmaceutics 12:6, pages 548.
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Karina Sanabria Ortiz, José R. Hernández Espinell, Desire Ortiz Torres, Vilmalí López-Mejías & Torsten Stelzer. (2019) Polymorphism in Solid Dispersions. Crystal Growth & Design 20:2, pages 713-722.
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Jie Zhang, Qin Shi, Jun Tao, Yayun Peng & Ting Cai. (2019) Impact of Polymer Enrichment at the Crystal–Liquid Interface on Crystallization Kinetics of Amorphous Solid Dispersions. Molecular Pharmaceutics 16:3, pages 1385-1396.
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Katla Venu Madhav & Veerabrahma Kishan. (2017) Self microemulsifying particles of loratadine for improved oral bioavailability: preparation, characterization and in vivo evaluation. Journal of Pharmaceutical Investigation 48:4, pages 497-508.
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Jay Prakash A. Yadav, Arvind K. Bansal & Sanyog Jain. (2018) Molecular Understanding and Implication of Structural Integrity in the Deformation Behavior of Binary Drug–Drug Eutectic Systems. Molecular Pharmaceutics 15:5, pages 1917-1927.
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José R. Hernández Espinell, Vilmalí López-Mejías & Torsten Stelzer. (2018) Revealing Polymorphic Phase Transformations in Polymer-Based Hot Melt Extrusion Processes. Crystal Growth & Design 18:4, pages 1995-2002.
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Zhen Chen, Chengyu Liu, Ling Zhang & Feng Qian. (2016) Dissolution Characteristics of Fast-Crystallizing β-Lapachone within Different Semicrystalline Microstructures of Polyethylene Glycol or Poly(ethylene oxide)–Poly(propylene oxide)–Poly(ethylene oxide) Triblock Copolymer. Crystal Growth & Design 16:9, pages 5367-5376.
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Jaewon Yang, Jin Young Park, Cheon Jung Lee, Hye Min Kim, Hyun Gu Lee, Na Gum Jang, Hyun Ah Ko, Seon Ah Cho, Dae Hyeok Yang & Gilson Khang. (2015) Improved Dissolution Behavior of Aceclofenac Loadings with Kollidon VA 64 Using Spray Drying and Rotary Evaporation Process. Polymer Korea 39:1, pages 6-12.
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Kayleen T. Campbell, Duncan Q. M. Craig & Tony McNally. (2014) Modification of ibuprofen drug release from poly(ethylene glycol) layered silicate nanocomposites prepared by hot-melt extrusion. Journal of Applied Polymer Science 131:10, pages n/a-n/a.
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Hywel D. Williams, Natalie L. Trevaskis, Susan A. Charman, Ravi M. Shanker, William N. Charman, Colin W. Pouton & Christopher J. H. Porter. (2013) Strategies to Address Low Drug Solubility in Discovery and Development. Pharmacological Reviews 65:1, pages 315-499.
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Qing Zhu, Michael T. Harris & Lynne S. Taylor. (2012) Modification of Crystallization Behavior in Drug/Polyethylene Glycol Solid Dispersions. Molecular Pharmaceutics 9:3, pages 546-553.
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Qing Zhu, Michael T. Harris & Lynne S. Taylor. (2011) Time-Resolved SAXS/WAXS Study of the Phase Behavior and Microstructural Evolution of Drug/PEG Solid Dispersions. Molecular Pharmaceutics 8:3, pages 932-939.
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Qing Zhu, Lynne S. Taylor & Michael T. Harris. (2010) Evaluation of the Microstructure of Semicrystalline Solid Dispersions. Molecular Pharmaceutics 7:4, pages 1291-1300.
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