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Pharmaceutical Development and Technology Volume 1, 1996 - Issue 2
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Research Article

Dissolution Enhancement of an Insoluble Drug by Physical Mixture with a Superdisintegrant: Optimization with a Simplex Lattice Design

Franca Ferrari Department of Pharmaceutical Chemistry, University of Pavia, Pavia, Italy
,
Moreno Bertoni Department of Pharmaceutical Chemistry, University of Pavia, Pavia, Italy
,
Cristina M. Bonferoni Department of Pharmaceutical Chemistry, University of Pavia, Pavia, Italy
,
Silvia Rossi Department of Pharmaceutical Chemistry, University of Pavia, Pavia, Italy
,
Carla Caramella Department of Pharmaceutical Chemistry, University of Pavia, Pavia, ItalyCorrespondence[email protected]
&
Gerard K. Bolhuis Department of Pharmaceutical Technology and Biopharmacy, University of Groningen, Groningen, The Netherlands
Pages 159-164 | Received 16 Jan 1996, Accepted 26 Feb 1996, Published online: 27 Sep 2008

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Saurabh M. Mishra & Bhagwan D. Rohera. (2017) An integrated, quality by design (QbD) approach for design, development and optimization of orally disintegrating tablet formulation of carbamazepine. Pharmaceutical Development and Technology 22:7, pages 889-903.
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Buyun Ding, Ping Chen, Yan Kong, Yingjie Zhai, Xin Pang, Jinfeng Dou & Guangxi Zhai. (2014) Preparation and evaluation of folate-modified lipid nanocapsules for quercetin delivery. Journal of Drug Targeting 22:1, pages 67-75.
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Darío Leonardi & Claudio J. Salomon. (2010) Influence of water uptake, gel network, and disintegration time on prednisone release from encapsulated solid dispersions. Pharmaceutical Development and Technology 15:2, pages 184-191.
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Articles from other publishers (8)

Jaime Conceição, Oluwatomide Adeoye, Helena Maria Cabral-Marques & José Manuel Sousa Lobo. (2018) Hydroxypropyl-β-Cyclodextrin and β-Cyclodextrin as Tablet Fillers for Direct Compression. AAPS PharmSciTech 19:6, pages 2710-2718.
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Muzna Sadia, Basel Arafat, Waqar Ahmed, Robert T. Forbes & Mohamed A. Alhnan. (2018) Channelled tablets: An innovative approach to accelerating drug release from 3D printed tablets. Journal of Controlled Release 269, pages 355-363.
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Silvia Rossi, Barbara Vigani, Antonella Puccio, Maria Bonferoni, Giuseppina Sandri & Franca Ferrari. (2017) Chitosan Ascorbate Nanoparticles for the Vaginal Delivery of Antibiotic Drugs in Atrophic Vaginitis. Marine Drugs 15:10, pages 319.
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Bettina Poller, Clare Strachan, Roland Broadbent & Greg F. Walker. (2017) A minitablet formulation made from electrospun nanofibers. European Journal of Pharmaceutics and Biopharmaceutics 114, pages 213-220.
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Michela Mori, Silvia Rossi, Franca Ferrari, Maria Cristina Bonferoni, Giuseppina Sandri, Theodora Chlapanidas, Maria Luisa Torre & Carla Caramella. (2016) Sponge-Like Dressings Based on the Association of Chitosan and Sericin for the Treatment of Chronic Skin Ulcers. I. Design of Experiments–Assisted Development. Journal of Pharmaceutical Sciences 105:3, pages 1180-1187.
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H. C Vadlamudi, Raju Y Prasanna, Y. B Rubia, J. Vulava & K.R Vandana. (2014) IN VITRO CHARACTERISTICS OF MODIFIED PULSINCAP FORMULATION WITH MESALAMINE FOR ULCERATIVE COLITIS TREATMENT. INDIAN DRUGS 51:03, pages 35-43.
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Darío Leonardi, María Gabriela Barrera, María Celina Lamas & Claudio Javier Salomón. (2007) Development of prednisone: Polyethylene glycol 6000 fast-release tablets from solid dispersions: Solid-state characterization, dissolution behavior, and formulation parameters. AAPS PharmSciTech 8:4.
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Jon Gabrielsson, Nils‐Olof Lindberg & Torbjörn Lundstedt. (2002) Multivariate methods in pharmaceutical applications. Journal of Chemometrics 16:3, pages 141-160.
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