259
Views
29
CrossRef citations to date
0
Altmetric
Research Article

Solubility Properties of Racemic Praziquantel and Its Enantiomers

, &
Pages 557-564 | Received 24 Sep 1997, Accepted 24 Apr 1998, Published online: 27 Sep 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (1)

Jabson Herber Profiro de Oliveira, Igor Eduardo Silva Arruda, José Izak Ribeiro de Araújo, Luise Lopes Chaves, Mônica Felts de La Rocca Soares & José Lamartine Soares-Sobrinho. (2022) Why do few drug delivery systems to combat neglected tropical diseases reach the market? An analysis from the technology’s stages. Expert Opinion on Therapeutic Patents 32:1, pages 89-114.
Read now

Articles from other publishers (28)

Peerapon Rapeenun, Charline J. J. Gerard, Clément Pinètre, Yohann Cartigny, Paul Tinnemans, René de Gelder, Adrian E. Flood & Joop H. ter Horst. (2023) Searching for Conglomerate Cocrystals of the Racemic Compound Praziquantel. Crystal Growth & Design.
Crossref
Andreas Waechtler, Bertram Cezanne, David Maillard, Rui Sun, Shaofang Wang, Jihua Wang & Achim Harder. (2023) Praziquantel – 50 Years of Research. ChemMedChem 18:12.
Crossref
Thomas Eason, Gisela Ramirez, Andrew J. Clulow, Malinda Salim & Ben J. Boyd. (2022) Revisiting the Dissolution of Praziquantel in Biorelevant Media and the Impact of Digestion of Milk on Drug Dissolution. Pharmaceutics 14:10, pages 2228.
Crossref
Christian Rodríguez-Ruiz, Reynaldo Salas-Zúñiga, María Obdulia Sánchez-Guadarrama, Alejandra Delgado-Díaz, Dea Herrera-Ruiz, Hugo Morales-Rojas & Herbert Höpfl. (2022) Structural, Physicochemical, and Biopharmaceutical Properties of Cocrystals with RS - and R -Praziquantel─Generation and Prolongation of the Supersaturation State in the Presence of Cellulosic Polymers . Crystal Growth & Design 22:10, pages 6023-6038.
Crossref
Edith K. Y. Tang, Gavin J. Partridge, Lindsey D. Woolley, Luke Pilmer & Lee Yong Lim. (2022) Effects of Formulation on the Palatability and Efficacy of In-Feed Praziquantel Medications for Marine Finfish Aquaculture. Marine Drugs 20:5, pages 323.
Crossref
Tatyana V. Volkova, Olga R. Simonova, Igor B. Levshin & German L. Perlovich. (2022) Chiral Recognition R- and RS- of New Antifungal: Complexation/Solubilization/Dissolution Thermodynamics and Permeability Assay. Pharmaceutics 14:4, pages 864.
Crossref
Reynaldo Salas-Zúñiga, Karina Mondragón-Vásquez, Sergio Alcalá-Alcalá, Enrique Lima, Herbert Höpfl, Dea Herrera-Ruiz & Hugo Morales-Rojas. (2021) Nanoconfinement of a Pharmaceutical Cocrystal with Praziquantel in Mesoporous Silica: The Influence of the Solid Form on Dissolution Enhancement. Molecular Pharmaceutics 19:2, pages 414-431.
Crossref
Christoph Saal, Axel Becker, Mireille Krier & Thomas Fuchß. (2022) Atropisomerism – A Neglected Way to Escape Out of Solubility Flatlands. Journal of Pharmaceutical Sciences 111:1, pages 206-213.
Crossref
Dezhi Yang, Junzi Cao, Tianyu Heng, Cheng Xing, Shiying Yang, Li Zhang, Yang Lu & Guanhua Du. (2021) Theoretical Calculation and Structural Analysis of the Cocrystals of Three Flavonols with Praziquantel. Crystal Growth & Design 21:4, pages 2292-2300.
Crossref
Rongrong Li, Xianlang Chen, Guanghong He, Chenglin Wu, Zhixing Gan, Zhicai He, Jia Zhao & Deman Han. (2020) The dissolution behaviour and thermodynamic properties calculation of praziquantel in pure and mixed organic solvents. The Journal of Chemical Thermodynamics 144, pages 106062.
Crossref
Ana Borrego-Sánchez, Esperanza Carazo, Beatrice Albertini, Nadia Passerini, Beatrice Perissutti, Pilar Cerezo, César Viseras, A. Hernández-Laguna, Carola Aguzzi & C. Ignacio Sainz-Díaz. (2018) Conformational polymorphic changes in the crystal structure of the chiral antiparasitic drug praziquantel and interactions with calcium carbonate. European Journal of Pharmaceutics and Biopharmaceutics 132, pages 180-191.
Crossref
Debora Zanolla, Beatrice Perissutti, Nadia Passerini, Michele R. Chierotti, Dritan Hasa, Dario Voinovich, Lara Gigli, Nicola Demitri, Silvano Geremia, Jennifer Keiser, Paolo Cerreia Vioglio & Beatrice Albertini. (2018) A new soluble and bioactive polymorph of praziquantel. European Journal of Pharmaceutics and Biopharmaceutics 127, pages 19-28.
Crossref
Bin Jiang, Xiao-Nong Zhou, Hao-Bing Zhang, Yi Tao, Le-Le Huo & Ni Liu. (2017) Slow-release praziquantel for dogs: presentation of a new formulation for echinococcosis control. Infectious Diseases of Poverty 6:1.
Crossref
L. Isabell Immohr & Miriam Pein-Hackelbusch. (2017) Development of stereoselective e-tongue sensors considering the sensor performance using specific quality attributes—A bottom up approach. Sensors and Actuators B: Chemical 253, pages 868-878.
Crossref
Beatrice Perissutti, Nadia Passerini, Ramona Trastullo, Jennifer Keiser, Debora Zanolla, Guglielmo Zingone, Dario Voinovich & Beatrice Albertini. (2017) An explorative analysis of process and formulation variables affecting comilling in a vibrational mill: The case of praziquantel. International Journal of Pharmaceutics 533:2, pages 402-412.
Crossref
Martina Cugovčan, Jasna Jablan, Jasmina Lovrić, Dominik Cinčić, Nives Galić & Mario Jug. (2017) Biopharmaceutical characterization of praziquantel cocrystals and cyclodextrin complexes prepared by grinding. Journal of Pharmaceutical and Biomedical Analysis 137, pages 42-53.
Crossref
Ana Borrego-Sánchez, Alfonso Hernández-Laguna & C. Ignacio Sainz-Díaz. (2017) Molecular modeling and infrared and Raman spectroscopy of the crystal structure of the chiral antiparasitic drug Praziquantel. Journal of Molecular Modeling 23:4.
Crossref
William AcreeJr.Jr. & James S. Chickos. (2017) Phase Transition Enthalpy Measurements of Organic and Organometallic Compounds and Ionic Liquids. Sublimation, Vaporization, and Fusion Enthalpies from 1880 to 2015. Part 2. C11–C192. Journal of Physical and Chemical Reference Data 46:1.
Crossref
Emanuel D. Costa, Josefina Priotti, Silvina Orlandi, Darío Leonardi, María C. Lamas, Teresa G. Nunes, Hermínio P. Diogo, Claudio J. Salomon & M. João Ferreira. (2016) Unexpected solvent impact in the crystallinity of praziquantel / poly(vinylpyrrolidone) formulations. A solubility, DSC and solid-state NMR study. International Journal of Pharmaceutics 511:2, pages 983-993.
Crossref
Mohamed A. Dkhil, Dina A. Nafady, Marwa S. M. Diab, Amira A. Bauomy & Saleh Al-Quraishy. 2016. Nanoparticles in the Fight Against Parasites. Nanoparticles in the Fight Against Parasites 191 205 .
Eva C. Arrúa, M.João G. Ferreira, Claudio J. Salomon & Teresa G. Nunes. (2015) Elucidating the guest-host interactions and complex formation of praziquantel and cyclodextrin derivatives by 13 C and 15 N solid-state NMR spectroscopy. International Journal of Pharmaceutics 496:2, pages 812-821.
Crossref
Ramona Trastullo, Luisa Stella Dolci, Nadia Passerini & Beatrice Albertini. (2015) Development of flexible and dispersible oral formulations containing praziquantel for potential schistosomiasis treatment of pre-school age children. International Journal of Pharmaceutics 495:1, pages 536-550.
Crossref
Alka Ahuja, Sanjula Baboota, Javed Ali & Gulam Mustafa. 2011. Cyclodextrins in Pharmaceutics, Cosmetics, and Biomedicine. Cyclodextrins in Pharmaceutics, Cosmetics, and Biomedicine 19 43 .
Stratos Maragos, Helen Archontaki, Panos Macheras & Georgia Valsami. (2009) Effect of Cyclodextrin Complexation on the Aqueous Solubility and Solubility/Dose Ratio of Praziquantel. AAPS PharmSciTech 10:4.
Crossref
Nadia Passerini, Beatrice Albertini, Beatrice Perissutti & Lorenzo Rodriguez. (2006) Evaluation of melt granulation and ultrasonic spray congealing as techniques to enhance the dissolution of praziquantel. International Journal of Pharmaceutics 318:1-2, pages 92-102.
Crossref
Elka Touitou, Biana Godin, Thirumala Kommuru, Mohsen Afouna & Indra Reddy. 2004. Chirality in Drug Design and Development. Chirality in Drug Design and Development.
István Hermecz. 2003. 219 353 .
James S Chickos & William E Acree. (2002) Total phase change entropies and enthalpies. Thermochimica Acta 395:1-2, pages 59-113.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.