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Prehospital Emergency Care Volume 14, 2010 - Issue 2
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Original Contributions

Out-of-Hospital Fluid in Severe Sepsis: Effect on Early Resuscitation in the Emergency Department

Christopher W. Seymour From the Division of Pulmonary & Critical Care Medicine, University of Washington (CWS, CRC, CHG), Seattle, Washington; the Division of Pulmonary & Critical Care Medicine, Hospital of the University of Pennsylvania (MEK), Philadelphia, Pennsylvania; the Department of Emergency Medicine, Hospital of the University of Pennsylvania (JH, DFG, RAB), Philadelphia, Pennsylvania; and King County Medic One, Division of General Internal Medicine, University of Washington (TDR), Seattle, Washington.Correspondence[email protected]
, MD,
Colin R. Cooke From the Division of Pulmonary & Critical Care Medicine, University of Washington (CWS, CRC, CHG), Seattle, Washington; the Division of Pulmonary & Critical Care Medicine, Hospital of the University of Pennsylvania (MEK), Philadelphia, Pennsylvania; the Department of Emergency Medicine, Hospital of the University of Pennsylvania (JH, DFG, RAB), Philadelphia, Pennsylvania; and King County Medic One, Division of General Internal Medicine, University of Washington (TDR), Seattle, Washington.
, MD, MSCE,
Mark E. Mikkelsen From the Division of Pulmonary & Critical Care Medicine, University of Washington (CWS, CRC, CHG), Seattle, Washington; the Division of Pulmonary & Critical Care Medicine, Hospital of the University of Pennsylvania (MEK), Philadelphia, Pennsylvania; the Department of Emergency Medicine, Hospital of the University of Pennsylvania (JH, DFG, RAB), Philadelphia, Pennsylvania; and King County Medic One, Division of General Internal Medicine, University of Washington (TDR), Seattle, Washington.
,
Julie Hylton From the Division of Pulmonary & Critical Care Medicine, University of Washington (CWS, CRC, CHG), Seattle, Washington; the Division of Pulmonary & Critical Care Medicine, Hospital of the University of Pennsylvania (MEK), Philadelphia, Pennsylvania; the Department of Emergency Medicine, Hospital of the University of Pennsylvania (JH, DFG, RAB), Philadelphia, Pennsylvania; and King County Medic One, Division of General Internal Medicine, University of Washington (TDR), Seattle, Washington.
, BS,
Tom D. Rea From the Division of Pulmonary & Critical Care Medicine, University of Washington (CWS, CRC, CHG), Seattle, Washington; the Division of Pulmonary & Critical Care Medicine, Hospital of the University of Pennsylvania (MEK), Philadelphia, Pennsylvania; the Department of Emergency Medicine, Hospital of the University of Pennsylvania (JH, DFG, RAB), Philadelphia, Pennsylvania; and King County Medic One, Division of General Internal Medicine, University of Washington (TDR), Seattle, Washington.
, MD, MPH,
Christopher H. Goss From the Division of Pulmonary & Critical Care Medicine, University of Washington (CWS, CRC, CHG), Seattle, Washington; the Division of Pulmonary & Critical Care Medicine, Hospital of the University of Pennsylvania (MEK), Philadelphia, Pennsylvania; the Department of Emergency Medicine, Hospital of the University of Pennsylvania (JH, DFG, RAB), Philadelphia, Pennsylvania; and King County Medic One, Division of General Internal Medicine, University of Washington (TDR), Seattle, Washington.
, MD, MSc,
David F. Gaieski From the Division of Pulmonary & Critical Care Medicine, University of Washington (CWS, CRC, CHG), Seattle, Washington; the Division of Pulmonary & Critical Care Medicine, Hospital of the University of Pennsylvania (MEK), Philadelphia, Pennsylvania; the Department of Emergency Medicine, Hospital of the University of Pennsylvania (JH, DFG, RAB), Philadelphia, Pennsylvania; and King County Medic One, Division of General Internal Medicine, University of Washington (TDR), Seattle, Washington.
, MD &
Roger A. Band From the Division of Pulmonary & Critical Care Medicine, University of Washington (CWS, CRC, CHG), Seattle, Washington; the Division of Pulmonary & Critical Care Medicine, Hospital of the University of Pennsylvania (MEK), Philadelphia, Pennsylvania; the Department of Emergency Medicine, Hospital of the University of Pennsylvania (JH, DFG, RAB), Philadelphia, Pennsylvania; and King County Medic One, Division of General Internal Medicine, University of Washington (TDR), Seattle, Washington.
, MD show all
Pages 145-152 | Received 27 Jun 2009, Accepted 19 Aug 2009, Published online: 03 Mar 2010

Citations (47)

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Nathaniel S. Miller, Mehul D. Patel, Jefferson G. Williams, Michael W. Bachman, Julianne M. Cyr, José G. Cabañas & Jane H. Brice. (2023) Prehospital Fluid Administration for Suspected Sepsis in a Large EMS System: Opportunities to Improve Goal Fluid Delivery. Prehospital Emergency Care 27:6, pages 769-774.
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Emily B. Brant, Jason Kennedy, Christian Martin-Gill, Vanessa Jackson, Octavia M. Peck Palmer, Clifton W. Callaway, Jeremy M. Kahn, Donald M. Yealy, Derek C. Angus & Christopher W. Seymour. (2020) Association Between Intravenous Fluid Bolus and Biomarker Trajectory During Prehospital Care. Prehospital Emergency Care 24:2, pages 196-203.
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Maia Dorsett, Melissa Kroll, Clark S. Smith, Phillip Asaro, Stephen Y. Liang & Hawnwan P. Moy. (2017) qSOFA Has Poor Sensitivity for Prehospital Identification of Severe Sepsis and Septic Shock. Prehospital Emergency Care 21:4, pages 489-497.
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Allison C. Barrett, Jonathan R. Studnek, Michael A. Puskarich & Alan E. Jones. (2016) Utilizing Geographic Information Systems to Identify Clusters of Severe Sepsis Patients Presenting in the Out-of-Hospital Environment. Prehospital Emergency Care 20:2, pages 200-205.
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Patrick J. Coppler, Rajagopala Padmanabhan, Christian Martin-Gill, Clifton W. Callaway, Donald M. Yealy & Christopher W. Seymour. (2016) Accuracy of Prehospital Intravenous Fluid Volume Measurement by Emergency Medical Services. Prehospital Emergency Care 20:1, pages 125-131.
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Lena C. W. van der Wekken, Nadia Alam, Frits Holleman, Pieternel van Exter, Mark H. H. Kramer & Prabath W. B. Nanayakkara. (2016) Epidemiology of Sepsis and Its Recognition by Emergency Medical Services Personnel in the Netherlands. Prehospital Emergency Care 20:1, pages 90-96.
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Adam Frisch, Shayla Cammarata, Vincent N. Mosesso$suffix/text()$suffix/text() & Christian Martin-Gill. (2013) Multivariate Analysis of Successful Intravenous Line Placement in the Prehospital Setting. Prehospital Emergency Care 17:1, pages 46-50.
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Christopher W. Seymour. (2011) Improving the Diagnosis of Infection During Out-of-Hospital Emergency Care: Are Biomarkers the Next Step?. Prehospital Emergency Care 15:3, pages 439-441.
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Brian Suffoletto, Adam Frisch, Arjun Prabhu, Jeffrey Kristan, Francis X. Guyette & Clifton W. Callaway. (2011) Prediction of Serious Infection During Prehospital Emergency Care. Prehospital Emergency Care 15:3, pages 325-330.
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Ishaq Lat, Craig M. Coopersmith, Daniel De Backer & Craig M. Coopersmith. (2021) The surviving sepsis campaign: fluid resuscitation and vasopressor therapy research priorities in adult patients. Intensive Care Medicine Experimental 9:1.
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Timothy P. George, Hei Kit Chan, Remle P. Crowe, Jeffrey L. Jarvis, Jan O. Jansen, Ryan M. Huebinger & Henry E. Wang. (2020) Clinical characteristics and course of out‐of‐hospital shock in a national emergency medical services cohort. Journal of the American College of Emergency Physicians Open 1:4, pages 432-439.
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Steven J. Weiss, Angel Guerrero, Christian Root-Bowman, Amy Ernst, Kurt Krumperman, Jon Femling & Phil Froman. (2019) Sepsis alerts in EMS and the results of pre-hospital ETCO2. The American Journal of Emergency Medicine 37:8, pages 1505-1509.
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Robert S. Green, Andrew H. Travers, Edward Cain, Samuel G. Campbell, Jan L. Jensen, David A. Petrie, Mete Erdogan, Gredi Patrick & Ward Patrick. (2016) Paramedic Recognition of Sepsis in the Prehospital Setting: A Prospective Observational Study. Emergency Medicine International 2016, pages 1-5.
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Donald M Yealy, David T Huang, Anthony Delaney, Marian Knight, Adrienne G Randolph, Ron Daniels & Tim Nutbeam. (2015) Recognizing and managing sepsis: what needs to be done?. BMC Medicine 13:1.
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C.E. Wrede & K. Reinhart. 2015. Weiterbildung Notfallmedizin. Weiterbildung Notfallmedizin 127 135 .
Pierre Squara. (2014) Central venous oxygenation: when physiology explains apparent discrepancies. Critical Care 18:5.
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Amado Alejandro Baez, Priscilla Hanudel & Susan Renee Wilcox. (2013) The Prehospital Sepsis Project: Out-of-Hospital Physiologic Predictors of Sepsis Outcomes. Prehospital and Disaster Medicine 28:6, pages 632-635.
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Graham McClellandPaul Younger. (2013) A study into pre-alerts to North East hospitals for sepsis. Journal of Paramedic Practice 5:7, pages 408-415.
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Wayne F. Guerra, Thomas R. Mayfield, Mary S. Meyers, Anne E. Clouatre & John C. Riccio. (2013) Early Detection and Treatment of Patients with Severe Sepsis by Prehospital Personnel. The Journal of Emergency Medicine 44:6, pages 1116-1125.
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Christopher W. Seymour, Thomas D. Rea, Jeremy M. Kahn, Allan J. Walkey, Donald M. Yealy & Derek C. Angus. (2012) Severe Sepsis in Pre-Hospital Emergency Care. American Journal of Respiratory and Critical Care Medicine 186:12, pages 1264-1271.
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Christopher W. Seymour, Colin R. Cooke, Paul L. Hebert & Thomas D. Rea. (2012) Intravenous Access During Out-of-Hospital Emergency Care of Noninjured Patients: A Population-Based Outcome Study. Annals of Emergency Medicine 59:4, pages 296-303.
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