1,197
Views
51
CrossRef citations to date
0
Altmetric
FOCUS ON EMS RESEARCH DESIGN

Design of the Study of Tranexamic Acid during Air Medical Prehospital Transport (STAAMP) Trial: Addressing the Knowledge Gaps

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Lena M. Napolitano. (2021) Hemostatic defects in massive transfusion: an update and treatment recommendations. Expert Review of Hematology 14:2, pages 219-239.
Read now
David S. Strosberg, Michelle C. Nguyen, Lisa Mostafavifar, Howard Mell & David C. Evans. (2016) Development of a Prehospital Tranexamic Acid Administration Protocol. Prehospital Emergency Care 20:4, pages 462-466.
Read now
Joshua B. Brown, Francis X. Guyette, Matthew D. Neal, Jeffrey A. Claridge, Brian J. Daley, Brian G. Harbrecht, Richard S. Miller, Herb A. Phelan, Peter W. Adams, Barbara J. Early, Andrew B. Peitzman, Timothy R. Billiar & Jason L. Sperry. (2015) Taking the Blood Bank to the Field: The Design and Rationale of the Prehospital Air Medical Plasma (PAMPer) Trial. Prehospital Emergency Care 19:3, pages 343-350.
Read now

Articles from other publishers (48)

Kristina J. Nicholson, Samuel A. Tisherman & Andrew B. Peitzman. 2024. Current Therapy of Trauma and Surgical Critical Care. Current Therapy of Trauma and Surgical Critical Care 448 455.e2 .
Andrew-Paul Deeb, Francis X. Guyette, Brian J. Daley, Richard S. Miller, Brian G. Harbrecht, Jeffrey A. Claridge, Herb A. Phelan, Brian J. Eastridge, Bellal Joseph, Raminder Nirula, Gary A. Vercruysse, Jason L. Sperry & Joshua B. Brown. (2023) Time to early resuscitative intervention association with mortality in trauma patients at risk for hemorrhage. Journal of Trauma and Acute Care Surgery 94:4, pages 504-512.
Crossref
Katherine M. Reitz, Amanda R. Phillips, Edith Tzeng, Michel S. Makaroun, Christine M. Leeper & Nathan L. Liang. (2022) Characterization of immediate and early mortality after repair of ruptured abdominal aortic aneurysm. Journal of Vascular Surgery 76:6, pages 1578-1587.e5.
Crossref
Ayman El-Menyar, Khalid Ahmed, Suhail Hakim, Ahad Kanbar, Saji Mathradikkal, Tariq Siddiqui, Hisham Jogol, Basil Younis, Ibrahim Taha, Ismail Mahmood, Ahmed Ajaj, Sajid Atique, Abubaker Alaieb, Ahmed Abdel-Aziz Bahey, Mohammad Asim, Guillaume Alinier, Nicholas R. Castle, Ahammed Mekkodathil, Sandro Rizoli & Hassan Al-Thani. (2021) Efficacy and safety of the second in-hospital dose of tranexamic acid after receiving the prehospital dose: double-blind randomized controlled clinical trial in a level 1 trauma center. European Journal of Trauma and Emergency Surgery 48:4, pages 3089-3099.
Crossref
Marvin Mecwan, Jinghang Li, Natashya Falcone, Menekse Ermis, Emily Torres, Ramon Morales, Alireza Hassani, Reihaneh Haghniaz, Kalpana Mandal, Saurabh Sharma, Surjendu Maity, Fatemeh Zehtabi, Behnam Zamanian, Rondinelli Herculano, Mohsen Akbari, Johnson V. John & Ali Khademhosseini. (2022) Recent advances in biopolymer-based hemostatic materials. Regenerative Biomaterials 9.
Crossref
Hunter B. Moore, Matthew D. Neal, Marnie Bertolet, Brian A. Joughin, Michael B. Yaffe, Christopher D. Barrett, Molly A. Bird, Russell P. Tracy, Ernest E Moore, Jason L. Sperry, Brian S. Zuckerbraun, Myung S. Park, Mitchell J. Cohen, Stephen R. Wisniewski & James H. Morrissey. (2022) Proteomics of Coagulopathy Following Injury Reveals Limitations of Using Laboratory Assessment to Define Trauma-Induced Coagulopathy to Predict Massive Transfusion. Annals of Surgery Open 3:2, pages e167.
Crossref
Sebastian Imach, Arasch Wafaisade, Rolf Lefering, Andreas Böhmer, Mark Schieren, Victor Suárez & Matthias Fröhlich. (2021) The impact of prehospital tranexamic acid on mortality and transfusion requirements: match-pair analysis from the nationwide German TraumaRegister DGU®. Critical Care 25:1.
Crossref
Jean Wong, Ronald B. George, Ciara M. Hanley, Chadi Saliba, Doreen A. Yee & Angela Jerath. (2021) Tranexamic acid: current use in obstetrics, major orthopedic, and trauma surgeryL’acide tranexamique : utilisation actuelle en obstétrique, en chirurgie orthopédique majeure et en traumatologie. Canadian Journal of Anesthesia/Journal canadien d'anesthésie 68:6, pages 894-917.
Crossref
Biswadev Mitra, Stephen Bernard, Dashiell Gantner, Brian Burns, Michael C Reade, Lynnette Murray, Tony Trapani, Veronica Pitt, Colin McArthur, Andrew Forbes, Marc Maegele & Russell L Gruen. (2021) Protocol for a multicentre prehospital randomised controlled trial investigating tranexamic acid in severe trauma: the PATCH-Trauma trial. BMJ Open 11:3, pages e046522.
Crossref
Katherine M. Reitz, Andrew D. Althouse & Jason L. Sperry. 2021. Trauma Induced Coagulopathy. Trauma Induced Coagulopathy 679 692 .
Andrew-Paul Deeb & Joshua B. Brown. 2021. Trauma Induced Coagulopathy. Trauma Induced Coagulopathy 495 512 .
Dominik F. Draxler, Robert L. Medcalf & Russell L. Gruen. 2021. Trauma Induced Coagulopathy. Trauma Induced Coagulopathy 455 472 .
Francis X. Guyette, Joshua B. Brown, Mazen S. Zenati, Barbara J. Early-Young, Peter W. Adams, Brian J. Eastridge, Raminder Nirula, Gary A. Vercruysse, Terence O’Keeffe, Bellal Joseph, Louis H. Alarcon, Clifton W. Callaway, Brian S. Zuckerbraun, Matthew D. Neal, Raquel M. Forsythe, Matthew R. Rosengart, Timothy R. Billiar, Donald M. Yealy, Andrew B. Peitzman & Jason L. Sperry. (2020) Tranexamic Acid During Prehospital Transport in Patients at Risk for Hemorrhage After Injury. JAMA Surgery.
Crossref
Francois-Xavier Ageron, Angele Gayet-Ageron, Katharine Ker, Timothy J. Coats, Haleema Shakur-Still, Ian Roberts, Aasia Kayani, Amber Geer, Bernard Ndungu, Bukola Fawole, Catherine Gilliam, Cecelia Adetayo, Collette Barrow, Danielle Beaumont, Danielle Prowse, David I'Anson, Eni Balogun, Hakim Miah, Haleema Shakur-Still, Ian Roberts, Imogen Brooks, Julio Onandia, Katharine Ker, Kiran Javaid, Laura Suncuan, Lauren Frimley, Mia Reid, Monica Arribas, Myriam Benyahia, Olujide Okunade, Phil Edwards, Rizwana Chaudhri, Sergey Kostrov, Sneha Kansagra & Tracey Pepple. (2020) Effect of tranexamic acid by baseline risk of death in acute bleeding patients: a meta-analysis of individual patient-level data from 28 333 patients. British Journal of Anaesthesia 124:6, pages 676-683.
Crossref
Sara P. Myers & Matthew D. Neal. (2020) Venous thromboembolism after tranexamic acid administration: legitimate risk or statistical confounder?. ANZ Journal of Surgery 90:4, pages 425-426.
Crossref
Ayman El-Menyar, Brijesh Sathian, Bianca M. Wahlen, Husham Abdelrahman, Ruben Peralta, Hassan Al-Thani & Sandro Rizoli. (2020) Prehospital administration of tranexamic acid in trauma patients: A 1:1 matched comparative study from a level 1 trauma center. The American Journal of Emergency Medicine 38:2, pages 266-271.
Crossref
Justin E. Richards, Ron E. Samet, A. Kennedy Koerner & Thomas E. Grissom. (2019) Tranexamic Acid in the Perioperative Period. Advances in Anesthesia 37, pages 87-110.
Crossref
Aditya Girish, DaShawn A. Hickman, Ankush Banerjee, Norman Luc, Yifeng Ma, Kenji Miyazawa, Ujjal D.S. Sekhon, Michael Sun, Stephanie Huang & Anirban Sen Gupta. (2019) Trauma‐targeted delivery of tranexamic acid improves hemostasis and survival in rat liver hemorrhage model. Journal of Thrombosis and Haemostasis 17:10, pages 1632-1644.
Crossref
Kieran Walsh, Francis O’Keeffe & Biswadev Mitra. (2019) Geographical Variance in the Use of Tranexamic Acid for Major Trauma Patients. Medicina 55:9, pages 561.
Crossref
Thomas E. Grissom. (2019) Walking the Tightrope of Bleeding Control: Fibrinolysis in Trauma. Anesthesia & Analgesia 129:3, pages 644-646.
Crossref
Sara P. Myers, Matthew E. Kutcher, Matthew R. Rosengart, Jason L. Sperry, Andrew B. Peitzman, Joshua B. Brown & Matthew D. Neal. (2019) Tranexamic acid administration is associated with an increased risk of posttraumatic venous thromboembolism. Journal of Trauma and Acute Care Surgery 86:1, pages 20-27.
Crossref
Ryan M. Boudreau, Keshav K. Deshpande, Gregory M. Day, William R. Hinckley, Nicole Harger, Timothy A. Pritts, Amy T. Makley & Michael D. Goodman. (2019) Prehospital Tranexamic Acid Administration During Aeromedical Transport After Injury. Journal of Surgical Research 233, pages 132-138.
Crossref
Ayman El-Menyar, Brijesh Sathian, Mohammed Asim, Rifat Latifi & Hassan Al-Thani. (2018) Efficacy of prehospital administration of tranexamic acid in trauma patients: A meta-analysis of the randomized controlled trials. The American Journal of Emergency Medicine 36:6, pages 1079-1087.
Crossref
Michael C. Johnson, Abdul Alarhayem, Victor Convertino, Robert Carter, Kevin Chung, Ronald Stewart, John Myers, Daniel Dent, Lilian Liao, Ramon Cestero, Susannah Nicholson, Mark Muir, Martin Schwacha, David Wampler, Mark DeRosa & Brian Eastridge. (2018) Compensatory Reserve Index: Performance of A Novel Monitoring Technology to Identify the Bleeding Trauma Patient. Shock 49:3, pages 295-300.
Crossref
DaShawn A. Hickman, Christa L. Pawlowski, Andrew Shevitz, Norman F. Luc, Ann Kim, Aditya Girish, Joyann Marks, Simi Ganjoo, Stephanie Huang, Edward Niedoba, Ujjal D. S. Sekhon, Michael Sun, Mitchell Dyer, Matthew D. Neal, Vikram S. Kashyap & Anirban Sen Gupta. (2018) Intravenous synthetic platelet (SynthoPlate) nanoconstructs reduce bleeding and improve ‘golden hour’ survival in a porcine model of traumatic arterial hemorrhage. Scientific Reports 8:1.
Crossref
Michael S. Lallemand, Donald M. Moe, John M. McClellan, Michael Loughren, Shannon Marko, Matthew J. Eckert & Matthew J. Martin. (2018) No intravenous access, no problem: Intraosseous administration of tranexamic acid is as effective as intravenous in a porcine hemorrhage model. Journal of Trauma and Acute Care Surgery 84:2, pages 379-385.
Crossref
Angèle Gayet-Ageron, David Prieto-Merino, Katharine Ker, Haleema Shakur, François-Xavier Ageron, Ian Roberts, Aasia Kayani, Amber Geer, Bernard Ndungu, Bukola Fawole, Catherine Gilliam, Cecelia Adetayo, Collette Barrow, Danielle Beaumont, Danielle Prowse, David I'Anson, Eni Balogun, Hakim Miah, Haleema Shakur, Ian Roberts, Imogen Brooks, Julio Onandia, Katharine Ker, Kiran Javaid, Laura Suncuan, Lauren Frimley, Mia Reid, Monica Arribas, Myriam Benyahia, Olujide Okunade, Phil Edwards, Rizwana Chaudhri, Sergey Kostrov, Sneha Kansagra & Tracey Pepple. (2018) Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40 138 bleeding patients. The Lancet 391:10116, pages 125-132.
Crossref
DaShawn A. Hickman, Christa L. Pawlowski, Ujjal D. S. Sekhon, Joyann Marks & Anirban Sen Gupta. (2018) Biomaterials and Advanced Technologies for Hemostatic Management of Bleeding. Advanced Materials 30:4, pages 1700859.
Crossref
Benjamin R. Huebner, Warren C. Dorlac & Chris Cribari. (2017) Tranexamic Acid Use in Prehospital Uncontrolled Hemorrhage. Wilderness & Environmental Medicine 28:2, pages S50-S60.
Crossref
V. Zickenrott, I. Greb, A. Henkelmann, F. Balzer, S. Casu, L. Kaufner, C. von Heymann, K. Zacharowski & C. F. Weber. (2017) Vorhaltung von Tranexamsäure im deutschen RettungsdienstTranexamic acid in the German emergency medical service. Der Anaesthesist 66:4, pages 249-255.
Crossref
Lena M Napolitano. (2017) Prehospital tranexamic acid: what is the current evidence?. Trauma Surgery & Acute Care Open 2:1, pages e000056.
Crossref
Brian Cornelius. (2017) Air Medical Administration of Tranexamic Acid. Journal of Trauma Nursing 24:1, pages 30-33.
Crossref
Ricardo J. Ramirez, Philip C. Spinella & Grant V. Bochicchio. (2017) Tranexamic Acid Update in Trauma. Critical Care Clinics 33:1, pages 85-99.
Crossref
Arasch Wafaisade, Rolf Lefering, Bertil Bouillon, Andreas B. Böhmer, Michael Gäßler & Matthias Ruppert. (2016) Prehospital administration of tranexamic acid in trauma patients. Critical Care 20:1.
Crossref
Arne Driessen, Matthias Fröhlich, Nadine Schäfer, Manuel Mutschler, Jerome M. Defosse, Thomas Brockamp, Bertil Bouillon, Ewa K. Stürmer, Rolf Lefering & Marc Maegele. (2016) Prehospital volume resuscitation - Did evidence defeat the crystalloid dogma? An analysis of the TraumaRegister DGU® 2002–2012. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 24:1.
Crossref
Henna Wong, Nicola Curry & Simon J. Stanworth. (2016) Blood products and procoagulants in traumatic bleeding. Current Opinion in Critical Care 22:6, pages 598-606.
Crossref
J.W. Simmons & M.F. Powell. (2016) Acute traumatic coagulopathy: pathophysiology and resuscitation. British Journal of Anaesthesia 117, pages iii31-iii43.
Crossref
Jose V. Nable, Benjamin J. Lawner & William J. Brady. (2016) 2016: emergency medical services annotated literature in review. The American Journal of Emergency Medicine 34:11, pages 2193-2199.
Crossref
Ronald Chang, Jessica C. Cardenas, Charles E. Wade & John B. Holcomb. (2016) Advances in the understanding of trauma-induced coagulopathy. Blood 128:8, pages 1043-1049.
Crossref
D. Aedo-Martín, R. García-Cañas, R. Navarro-Suay, M. Martínez-Roldán, R. Baños-Turza & R. Tamburri-Bariain. (2016) Use of tranexamic acid in combat casualties. Experience of the Spanish medical corps. Clinical series and literature review. Revista Española de Cirugía Ortopédica y Traumatología (English Edition) 60:3, pages 200-205.
Crossref
D. Aedo-Martín, R. García-Cañas, R. Navarro-Suay, M. Martínez-Roldán, R. Baños-Turza & R. Tamburri-Bariain. (2016) Empleo de ácido tranexámico en el herido de combate, experiencia de la sanidad militar española. Serie de casos y revisión de la literatura. Revista Española de Cirugía Ortopédica y Traumatología 60:3, pages 200-205.
Crossref
Takeshi NISHIDA, Takahiro KINOSHITA & Kazuma YAMAKAWA. (2016) Traumatic coagulopathy and tranexamic acid. Japanese Journal of Thrombosis and Hemostasis 27:4, pages 436-443.
Crossref
Jill L. Sondeen, Margaret A. Hanson, Malcolm D. Prince, Rodolfo de Guzman, Irene A. Polykratis, James K. Aden, Andrew P. Cap & Michael A. Dubick. (2016) Double-blinded, placebo-controlled study of early tranexamic acid treatment in swine uncontrolled hemorrhage model. Journal of Trauma and Acute Care Surgery 80:1, pages 81-88.
Crossref
Dominik F. Draxler, Robert L. Medcalf & Russell L. Gruen. 2016. Trauma Induced Coagulopathy. Trauma Induced Coagulopathy 403 418 .
Sophia Binz, Jonathon McCollester, Scott Thomas, Joseph Miller, Timothy Pohlman, Dan Waxman, Faisal Shariff, Rebecca Tracy & Mark Walsh. (2015) CRASH-2 Study of Tranexamic Acid to Treat Bleeding in Trauma Patients: A Controversy Fueled by Science and Social Media. Journal of Blood Transfusion 2015, pages 1-12.
Crossref
Katharine Ker & Ian Roberts. (2015) Exploring redundant research into the effect of tranexamic acid on surgical bleeding: further analysis of a systematic review of randomised controlled trials. BMJ Open 5:8, pages e009460.
Crossref
Heather F. Pidcoke, Claire L. Isbell, Maryanne C. Herzig, Chriselda G. Fedyk, Beverly S. Schaffer, Kevin K. Chung, Christopher E. White, Steven E. Wolf, Charles E. Wade & Andrew P. Cap. (2015) Acute blood loss during burn and soft tissue excisions. Journal of Trauma and Acute Care Surgery 78:6, pages S39-S47.
Crossref
Rosemary L. Sparrow. (2015) Red Blood Cell Storage Duration and Trauma. Transfusion Medicine Reviews 29:2, pages 120-126.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.