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Review Article

Should biochemical markers of bone turnover be considered standard practice for safety pharmacology?

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Pages 195-204 | Received 17 Aug 2009, Accepted 22 Oct 2009, Published online: 01 Dec 2009

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K. Henriksen, C. Christiansen & M. A. Karsdal. (2015) Role of biochemical markers in the management of osteoporosis. Climacteric 18:sup2, pages 10-18.
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Jukka P Rissanen & Jussi M Halleen. (2010) Models and screening assays for drug discovery in osteoporosis. Expert Opinion on Drug Discovery 5:12, pages 1163-1174.
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M.A. Karsdal, F. Genovese, D.G.K. Rasmussen, A.C. Bay-Jensen, J.H. Mortensen, S. Holm Nielsen, N. Willumsen, C. Jensen, T. Manon-Jensen, L. Jennings, A.L. Reese-Petersen, K. Henriksen, J.M. Sand, C. Bager & D.J. Leeming. (2021) Considerations for understanding protein measurements: Identification of formation, degradation and more pathological relevant epitopes. Clinical Biochemistry 97, pages 11-24.
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Virginia Byers Kraus & Morten A. Karsdal. (2020) Osteoarthritis: Current Molecular Biomarkers and the Way Forward. Calcified Tissue International 109:3, pages 329-338.
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Morten Asser Karsdal, Virginia Byers Kraus, Diane Shevell, Anne Christine Bay-Jensen, Jörn Schattenberg, R. Rambabu Surabattula & Detlef Schuppan. (2021) Profiling and targeting connective tissue remodeling in autoimmunity - A novel paradigm for diagnosing and treating chronic diseases. Autoimmunity Reviews 20:1, pages 102706.
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Morten A. Karsdal, Samuel J. Daniels, Signe Holm Nielsen, Cecilie Bager, Daniel G.K. Rasmussen, Rohit Loomba, Rambabu Surabattula, Ida Falk Villesen, Yi Luo, Diane Shevell, Natasja S. Gudmann, Mette J. Nielsen, Jacob George, Rose Christian, Diana J. Leeming & Detlef Schuppan. (2020) Collagen biology and non‐invasive biomarkers of liver fibrosis. Liver International 40:4, pages 736-750.
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M.A. Karsdal. 2019. Biochemistry of Collagens, Laminins and Elastin. Biochemistry of Collagens, Laminins and Elastin xxiii xliv .
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V.B. Kraus, F.J. Blanco, M. Englund, M.A. Karsdal & L.S. Lohmander. (2015) Call for standardized definitions of osteoarthritis and risk stratification for clinical trials and clinical use. Osteoarthritis and Cartilage 23:8, pages 1233-1241.
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Jürgen Sandow. 2013. Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays. Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays 421 520 .
Kim Henriksen, Claus Christiansen & Morten Asser Karsdal. (2011) Serological biochemical markers of surrogate efficacy and safety as a novel approach to drug repositioning. Drug Discovery Today 16:21-22, pages 967-975.
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Morten A Karsdal, Thasia Woodworth, Kim Henriksen, Walter P Maksymowych, Harry Genant, Philippe Vergnaud, Claus Christiansen, Tanja Schubert, Per Qvist, Georg Schett, Adam Platt & Anne-Christine Bay-Jensen. (2011) Biochemical markers of ongoing joint damage in rheumatoid arthritis - current and future applications, limitations and opportunities. Arthritis Research & Therapy 13:2, pages 215.
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