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Original Article

Effects of Dietary Lipid Manipulation upon Rat Spleen Lymphocyte Functions and the Expression of Lymphocyte Surface Molecules

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Pages 119-132 | Published online: 13 Jul 2009

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Jaya T. Venkatraman & Wei-chia Chu. (1999) Effects of Dietary ω-3 and ω-6 Lipids and Vitamin E on Serum Cytokines, Lipid Mediators and Anti-DNA Antibodies in a Mouse Model for Rheumatoid Arthritis. Journal of the American College of Nutrition 18:6, pages 602-613.
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Ralf S. Mueller, Martin J. Fettman, Kristi Richardson, Rodney A. Hansen, Arianne Miller, Jody Magowitz & Gregory K. Ogilvie. (2005) Plasma and skin concentrations of polyunsaturated fatty acids before and after supplementation with n-3 fatty acids in dogs with atopic dermatitis. American Journal of Veterinary Research 66:5, pages 868-873.
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Jennifer M. Foley, Ken D. Stark, Sheri Zajchowski & Kelly A. Meckling. (2004) Fatty Acids and Exercise Affect Glucose Transport But Not Tumour Growth in F-344 Rats. Canadian Journal of Applied Physiology 29:5, pages 604-622.
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Parveen Yaqoob. (2007) Fatty acids and the immune system: from basic science to clinical applications. Proceedings of the Nutrition Society 63:1, pages 89-105.
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S. Kew, S. Wells, F. Thies, P.C. Calder, G.P. McNeill, P.T. Quinlan, G.T. Clark, H. Dombrowsky & A.D. Postle. (2003) The Effect of Eicosapentaenoic Acid on Rat Lymphocyte Proliferation Depends Upon Its Position in Dietary Triacylglycerols. The Journal of Nutrition 133:12, pages 4230-4238.
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Jean A. Hall, Katie A. Tooley, Joseph L. Gradin, Dennis E. Jewell & Rosemary C. Wander. (2003) Effects of dietary n-6 and n-3 fatty acids and vitamin E on the immune response of healthy geriatric dogs. American Journal of Veterinary Research 64:6, pages 762-772.
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Philip C. Calder. (2007) Dietary modification of inflammation with lipids. Proceedings of the Nutrition Society 61:3, pages 345-358.
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L. M. Hillyer & Bill Woodward. (2007) A comparison of the capacity of six cold-pressed plant oils to support development of acquired immune competence in the weanling mouse: superiority of low-linoleic-acid oils. British Journal of Nutrition 88:2, pages 171-181.
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P. C. Calder, P. Yaqoob, F. Thies, F. A. Wallace & E. A. Miles. (2007) Fatty acids and lymphocyte functions. British Journal of Nutrition 87:S1, pages S31-S48.
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Philip C. Calder. (2001) Polyunsaturated fatty acids, inflammation, and immunity. Lipids 36:9, pages 1007-1024.
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Philip C. Calder. (2001) The ratio of n-6 to n-3 fatty acids in the diet: Impact on T lymphocyte function. European Journal of Lipid Science and Technology 103:6, pages 390-398.
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Frank Thies, Gerhard Nebe-von-Caron, Jonathan R Powell, Parveen Yaqoob, Eric A Newsholme & Philip C Calder. (2001) Dietary supplementation with eicosapentaenoic acid, but not with other long-chain n−3 or n−6 polyunsaturated fatty acids, decreases natural killer cell activity in healthy subjects aged >55 y. The American Journal of Clinical Nutrition 73:3, pages 539-548.
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Y.W. Wang, C.J. Field & J.S. Sim. (2000) Dietary polyunsaturated fatty acids alter lymphocyte subset proportion and proliferation, serum immunoglobulin G concentration, and immune tissue development in chicks. Poultry Science 79:12, pages 1741-1748.
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Yaqoob, Pala, Cortina-Borja, Newsholme & Calder. (2000) Encapsulated fish oil enriched in alpha-tocopherol alters plasma phospholipid and mononuclear cell fatty acid compositions but not mononuclear cell functions. European Journal of Clinical Investigation 30:3, pages 260-274.
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Marguerite Moussa, Jean Tkaczuk, Jeannie Ragab, Jésus Garcia, Michel Abbal, Elie Ohayon, Jacques Ghisolfi & Jean-Paul Thouvenot. (2007) Relationship between the fatty acid composition of rat lymphocytes and immune functions. British Journal of Nutrition 83:3, pages 327-333.
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M. Moussa, J. Le Boucher, J. Garcia, J. Tkaczuk, J. Ragab, G. Dutot, E. Ohayon, J. Ghisolfi & J.P. Thouvenot. (2000) In vivo effects of olive oil-based lipid emulsion on lymphocyte activation in rats. Clinical Nutrition 19:1, pages 49-54.
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L.D. Peterson, F. Thies & P.C. Calder. (1999) Dose-dependent effects of dietary ?-linolenic acid on rat spleen lymphocyte functions. Prostaglandins, Leukotrienes and Essential Fatty Acids 61:1, pages 19-24.
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D.F. Horrobin & C.N. Bennett. (1999) Depression and bipolar disorder: relationships to impaired fatty acid and phospholipid metabolism and to diabetes, cardiovascular disease, immunological abnormalities, cancer, ageing and osteoporosis Possible candidate genes. Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) 60:4, pages 217-234.
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Taku Sasaki, Yusuke Kanke, Keita Kudoh, Yoshihisa Misawa, Jun Shimizu & Toshichika Takita. (1999) Effects of dietary docosahexaenoic acid on surface molecules involved in T cell proliferation. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1436:3, pages 519-530.
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P. C. Calder. (1999) Dietary fatty acids and the immune system. Lipids 34:S1, pages S137-S140.
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Parveen Yaqoob. (2008) Monounsaturated fats and immune function. Proceedings of the Nutrition Society 57:4, pages 511-520.
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Philip C. Calder. (2008) Dietary fatty acids and lymphocyte functions. Proceedings of the Nutrition Society 57:4, pages 487-502.
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G. Hornstra, C. A. Barth, C. Galli, R. P. Mensink, M. Mutanen, R. A. Riemersma, M. Roberfroid, K. Salminen, G. Vansant & P. M. Verschuren. (2007) Functional food science and the cardiovascular system. British Journal of Nutrition 80:S1, pages S113-S146.
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Peter Sanderson & Philip C. Calder. (1998) Dietary fish oil appears to prevent the activation of phospholipase C-γ in lymphocytes. Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism 1392:2-3, pages 300-308.
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Elizabeth A. Miles & Philip C. Calder. (2007) Modulation of immune function by dietary fatty acids. Proceedings of the Nutrition Society 57:02, pages 277-292.
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SANDERSON & CALDER. (2001) Dietary fish oil diminishes lymphocyte adhesion to macrophage and endothelial cell monolayers. Immunology 94:1, pages 79-87.
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L.D. Peterson, F. Thies, P. Sanderson, E.A. Newsholme & P.C. Calder. (1998) Low levels of eicosapentaenoic and docosahexaenoic acids mimic the effects of fish oil upon rat lymphocytes. Life Sciences 62:24, pages 2209-2217.
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P. Yaqoob. (1998) Monounsaturated fats and immune function. Brazilian Journal of Medical and Biological Research 31:4, pages 453-465.
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Lindsay E. Robinson & Catherine J. Field. (1998) Dietary Long-Chain (n-3) Fatty Acids Facilitate Immune Cell Activation in Sedentary, but not Exercise-Trained Rats. The Journal of Nutrition 128:3, pages 498-504.
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N.M. Jeffery, P. Sanderson, E.A. Newsholme & P.C. Calder. (1998) Characteristics of lipid and lymphocytes collected from the lymph of rats fed a low fat diet or high fat diets rich in N-6 or N-3 polyunsaturated fatty acids. Nutrition Research 18:2, pages 299-308.
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L. D. Peterson, N. M. Jeffery, F. Thies, P. Sanderson, E. A. Newsholme & P. C. Calder. (1998) Eicosapentaenoic and docosahexaenoic acids alter rat spleen leukocyte fatty acid composition and prostaglandin E2 production but have different effects on lymphocyte functions and cell-mediated immunity. Lipids 33:2, pages 171-180.
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Philip C. Calder. (2009) Dietary Fatty Acids and the Immune System. Nutrition Reviews 56:1, pages S70-S83.
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N.M. Jeffery, E.A. Newsholme & P.C. Calder. (1997) Level of polyunsaturated fatty acids and the n-6 to n-3 polyunsaturated fatty acid ratio in the rat diet alter serum lipid levels and lymphocyte functions. Prostaglandins, Leukotrienes and Essential Fatty Acids 57:2, pages 149-160.
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Nicola M. Jeffery, Mario Cortina, Eric A. Newsholme & Philip C. Calder. (2007) Effects of variations in the proportions of saturated, monounsaturated and polyunsaturated fatty acids in the rat diet on spleen lymphocyte functions. British Journal of Nutrition 77:5, pages 805-823.
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Philip C. Calder. (1997) N-3 Polyunsaturated fatty acids and immune cell function. Advances in Enzyme Regulation 37, pages 197-237.
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Philip C. Calder. (2007) Immunomodulatory and anti-inflammatory effects of n-3 polyunsaturated fatty acids. Proceedings of the Nutrition Society 55:2, pages 737-774.
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N. M. Jeffery, P. Sanderson, E. J. Sherrington, E. A. Newsholme & P. C. Calder. (1996) The ratio of n-6 to n-3 polyunsaturated fatty acids in the rat diet alters serum lipid levels and lymphocyte functions. Lipids 31:7, pages 737-745.
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Nicola M. Jeffery, Parveen Yaqoob, David Wiggins, Geoffrey F. Gibbons, Eric A. Newsholme & Philip C. Calder. (1996) Characterization of lipoprotein composition in rats fed different dietary lipids and of the effects of lipoproteins upon lymphocyte proliferation. The Journal of Nutritional Biochemistry 7:5, pages 282-292.
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Philip C. Calder. (2007) Effects of fatty acids and dietary lipids on cells of the immune system. Proceedings of the Nutrition Society 55:1B, pages 127-150.
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