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Original Article

Randomized placebo-controlled trial of an isoflavone supplement and menopausal symptoms in women

, , , &
Pages 85-92 | Received 13 Aug 1998, Accepted 17 Dec 1998, Published online: 03 Jul 2009

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Read on this site (22)

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Renée L. Simbalista, Adolfo V. Sauerbronn, José M. Aldrighi & José A.G. Arêas. (2010) Consumption of a Flaxseed-Rich Food Is Not More Effective Than a Placebo in Alleviating the Climacteric Symptoms of Postmenopausal Women. The Journal of Nutrition 140:2, pages 293-297.
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Stacie E. Geller, Lee P. Shulman, Richard B. van Breemen, Suzanne Banuvar, Ying Zhou, Geena Epstein, Samad Hedayat, Dejan Nikolic, Elizabeth C. Krause, Colleen E. Piersen, Judy L. Bolton, Guido F. Pauli & Norman R. Farnsworth. (2009) Safety and efficacy of black cohosh and red clover for the management of vasomotor symptoms. Menopause 16:6, pages 1156-1166.
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S. Basaria, A. Wisniewski, K. Dupree, T. Bruno, M. Y. Song, F. Yao, A. Ojumu, M. John & A. S. Dobs. (2014) Effect of high-dose isoflavones on cognition, quality of life, androgens, and lipoprotein in post-menopausal women. Journal of Endocrinological Investigation 32:2, pages 150-155.
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Laurie Kelly McCorryBella H. Mehta. 2009. Community Pharmacy Practice Case Studies. Community Pharmacy Practice Case Studies.
M. Diana van Die, Henry G. Burger, Kerry M. Bone, Marc M. Cohen & Helena J. Teede. (2009) Hypericum perforatum with Vitex agnus-castus in menopausal symptoms. Menopause 16:1, pages 156-163.
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Judith Simms-Cendan. 2008. Perimenopause. Perimenopause 1 12 .
Paola Albertazzi & David W. Purdie. (2008) Reprint of The nature and utility of the phytoestrogens: a review of the evidence. Maturitas 61:1-2, pages 214-226.
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Stacie E Geller & Laura Studee. 2008. Endometrium, The. Endometrium, The 771 784 .
Trevor J PowlesAnthony HowellD Gareth EvansEugene V MccloskeySue AshleyRosemary GreenhalghJenny AffenLesley Ann Flook & Alwynne Tidy. (2008) Red clover isoflavones are safe and well tolerated in women with a family history of breast cancer. Menopause International 14:1, pages 6-12.
Crossref
Heidi D Nelson. (2008) Menopause. The Lancet 371:9614, pages 760-770.
Crossref
Won O. Song, Ock Kyoung Chun, Inkyeong Hwang, Han Seung Shin, Bong-Gwan Kim, Kun Soo Kim, Sang-Yun Lee, Dayeon Shin & Sung G. Lee. (2007) Soy Isoflavones as Safe Functional Ingredients. Journal of Medicinal Food 10:4, pages 571-580.
Crossref
Deepti Cheema, Arri Coomarasamy & Tarek El-Toukhy. (2007) Non-hormonal therapy of post-menopausal vasomotor symptoms: a structured evidence-based review. Archives of Gynecology and Obstetrics 276:5, pages 463-469.
Crossref
Anne Lethaby, Jane Marjoribanks, Fredi Kronenberg, Helen Roberts, John Eden & Julie Brown. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
A. Monnier. (2007) Clinical management of adverse events in adjuvant therapy for hormone-responsive early breast cancer. Annals of Oncology 18, pages viii36-viii44.
Crossref
Wolfgang Wuttke, Hubertus Jarry & Dana Seidlová-Wuttke. (2007) Isoflavones—Safe food additives or dangerous drugs?. Ageing Research Reviews 6:2, pages 150-188.
Crossref
Clemens B. Tempfer, Eva-Katrin Bentz, Sepp Leodolter, Georg Tscherne, Ferdinand Reuss, Heide S. Cross & Johannes C. Huber. (2007) Phytoestrogens in clinical practice: a review of the literature. Fertility and Sterility 87:6, pages 1243-1249.
Crossref
Nick Panay. (2007) Integrating phytoestrogens with prescription medicines?A conservative clinical approach to vasomotor symptom management. Maturitas 57:1, pages 90-94.
Crossref
Laura Boehnke Michaud, Julie Phillips Karpinski, Kellie L. Jones & Janet Espirito. (2007) Dietary supplements in patients with cancer: Risks and key concepts, part 2. American Journal of Health-System Pharmacy 64:5, pages 467-480.
Crossref
Mesut Oktem, Derya Eroglu, Hilal B. Karahan, Nilgun Taskintuna, Esra Kuscu & Hulusi B. Zeyneloglu. (2007) Black cohosh and fluoxetine in the treatment of postmenopausal symptoms: A prospective, randomized trial. Advances in Therapy 24:2, pages 448-461.
Crossref
Joanna Thompson Coon, Max H. Pittler & Edzard Ernst. (2007) Trifolium pratense isoflavones in the treatment of menopausal hot flushes: A systematic review and meta-analysis. Phytomedicine 14:2-3, pages 153-159.
Crossref
Anne Nedrow. 2007. Integrative Medicine. Integrative Medicine 589 600 .
ADRIANE FUGH-BERMAN. 2007. Treatment of the Postmenopausal Woman. Treatment of the Postmenopausal Woman 683 690 .
Jeanne L. Shea. (2006) Cross-cultural comparison of women’s midlife symptom-reporting: a china study. Culture, Medicine and Psychiatry 30:3, pages 331-362.
Crossref
Laurence G. Howes, Jan B. Howes & David C. Knight. (2006) Isoflavone therapy for menopausal flushes: A systematic review and meta-analysis. Maturitas 55:3, pages 203-211.
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Mary I. Huang, Yael Nir, Bertha Chen, Rosa Schnyer & Rachel Manber. (2006) A randomized controlled pilot study of acupuncture for postmenopausal hot flashes: effect on nocturnal hot flashes and sleep quality. Fertility and Sterility 86:3, pages 700-710.
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Jacqueline E. Lewis, Leslie A. Nickell, Lilian U. Thompson, John P. Szalai, Alex Kiss & John R. Hilditch. (2006) A randomized controlled trial of the effect of dietary soy and flaxseed muffins on quality of life and hot flashes during menopause. Menopause 13:4, pages 631-642.
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Denise Tiran. (2006) Integrated healthcare: herbal remedies for menopausal symptoms. British Journal of Nursing 15:12, pages 645-648.
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Lila E. Nachtigall, Rodney J. Baber, Ronald Barentsen, Nancy Durand, Nick Panay, Joan Pitkin, Peter H.M. van de Weijer & Susan Wysocki. (2006) Complementary and Hormonal Therapy for Vasomotor Symptom Relief: A Conservative Clinical Approach. Journal of Obstetrics and Gynaecology Canada 28:4, pages 279-289.
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Nancy L. Booth, Colleen E. Piersen, Suzanne Banuvar, Stacie E. Geller, Lee P. Shulman & Norman R. Farnsworth. (2006) Clinical studies of red clover (Trifolium pratense) dietary supplements in menopause: a literature review. Menopause 13:2, pages 251-264.
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Aedin Cassidy, Paola Albertazzi, Inge Lise Nielsen, Wendy Hall, Gary Williamson, Inge Tetens, Steve Atkins, Heide Cross, Yannis Manios, Alicja Wolk, Claudia Steiner & Francesco Branca. (2007) Critical review of health effects of soyabean phyto-oestrogens in post-menopausal women. Proceedings of the Nutrition Society 65:1, pages 76-92.
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Paola Albertazzi. (2006) A Review of Non-Hormonal Options for the Relief of Menopausal Symptoms. Treatments in Endocrinology 5:2, pages 101-113.
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Takeshi USUI. (2006) Pharmaceutical Prospects of Phytoestrogens. Endocrine Journal 53:1, pages 7-20.
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Manja Reimann, Jutta Dierkes, Anja Carlsohn, Duncan Talbot, Marika Ferrari, Jesper Hallund, Wendy L Hall, Katerina Vafeiadou, Ulrich Huebner, Francesco Branca, Susanne Bugel, Christine M Williams, HJ Franz Zunft & Corinna Koebnick. (2006) Consumption of Soy Isoflavones Does Not Affect Plasma Total Homocysteine or Asymmetric Dimethylarginine Concentrations in Healthy Postmenopausal Women ,. The Journal of Nutrition 136:1, pages 100-105.
Crossref
Mary Ellen Rousseau. 2006. Handbook of Models for Human Aging. Handbook of Models for Human Aging 873 879 .
. 2006. Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions. Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions 1311 1317 .
Katherine Hanna, Alice Day, Sheila O'Neill, Carla Patterson & Philippa Lyons-Wall. (2005) Does scientific evidence support the use of non-prescription supplements for treatment of acute menopausal symptoms such as hot flushes?. Nutrition <html_ent glyph="@amp;" ascii="&"/> Dietetics 62:4, pages 138-151.
Crossref
Tieraona Low Dog. (2005) Menopause: a review of botanical dietary supplements. The American Journal of Medicine 118:12, pages 98-108.
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Gail B. Mahady. (2005) Do Soy Isoflavones Cause Endometrial Hyperplasia?. Nutrition Reviews 63:11, pages 392-397.
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Foo-Hoe Loh, Lay-Wai Khin, Seang-Mei Saw, Jeannette J.M. Lee & Ken Gu. (2005) The age of menopause and the menopause transition in a multiracial population: a nation-wide Singapore study. Maturitas 52:3-4, pages 169-180.
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Crossref
Stacie E. GellerLaura Studee. (2005) Botanical and Dietary Supplements for Menopausal Symptoms: What Works, What Does Not. Journal of Women's Health 14:7, pages 634-649.
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Melissa Melby, Xing-Gang Zhuo, Mituru Kimira, Naoko Ishiwata & Shaw Watanabe. 2005. Soy in Health and Disease Prevention. Soy in Health and Disease Prevention 87 106 .
Marieke O Verhoeven, Marius J van der Mooren, Peter H. M van de Weijer, Peter J. E Verdegem, Leontine M J van der Burgt & Peter Kenemans. (2005) Effect of a combination of isoflavones and Actaea racemosa Linnaeus on climacteric symptoms in healthy symptomatic perimenopausal women: a 12-week randomized, placebo-controlled, double-blind study. Menopause 12:4, pages 412-420.
Crossref
Debi SmolinskiDebra WollnerJennifer OrlowskiJessica CurcioJennifer NevelsLinda S. Kim. (2005) A Pilot Study to Examine a Combination Botanical for the Treatment of Menopausal Symptoms. The Journal of Alternative and Complementary Medicine 11:3, pages 483-489.
Crossref
Nadia F. Soliman. (2005) Treatment of vasomotor symptoms: Is there an alternative to hormone replacement therapy?. Reviews in Gynaecological Practice 5:2, pages 109-114.
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Carlo Campagnoli, Chiara Abbà, Simona Ambroggio, Clementina Peris, Marco Perona & Patrizia Sanseverino. (2005) Polyunsaturated fatty acids (PUFAs) might reduce hot flushes: an indication from two controlled trials on soy isoflavones alone and with a PUFA supplement. Maturitas 51:2, pages 127-134.
Crossref
V. Beck, U. Rohr & A. Jungbauer. (2005) Phytoestrogens derived from red clover: An alternative to estrogen replacement therapy?. The Journal of Steroid Biochemistry and Molecular Biology 94:5, pages 499-518.
Crossref
Julie McKee & Sara L. Warber. (2005) Integrative Therapies for Menopause. Southern Medical Journal 98:3, pages 319-326.
Crossref
Eini Nikander, Eeva-Marja Rutanen, Pekka Nieminen, Torsten Wahlström, Olavi Ylikorkala & Aila Tiitinen. (2005) Lack of effect of isoflavonoids on the vagina and endometrium in postmenopausal women. Fertility and Sterility 83:1, pages 137-142.
Crossref
Tieraona Low Dog. 2005. Women's Health in Complementary and Integrative Medicine. Women's Health in Complementary and Integrative Medicine 64 89 .
Bruce Kessel & Fredi Kronenberg. (2004) The role of complementary and alternative medicine in management of menopausal symptoms. Endocrinology and Metabolism Clinics of North America 33:4, pages 717-739.
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Erin E. Krebs, Kristine E. Ensrud, Roderick MacDonald & Timothy J. Wilt. (2004) Phytoestrogens for Treatment of Menopausal Symptoms: A Systematic Review. Obstetrics & Gynecology 104:4, pages 824-836.
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Tori Hudson. (2004) Women's Health Update. Alternative and Complementary Therapies 10:5, pages 285-288.
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Xiaobin Jia, Jun Chen, Huimin Lin & Ming Hu. (2004) Disposition of Flavonoids via Enteric Recycling: Enzyme-Transporter Coupling Affects Metabolism of Biochanin A and Formononetin and Excretion of Their Phase II Conjugates. Journal of Pharmacology and Experimental Therapeutics 310:3, pages 1103-1113.
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N.J. Bundred & L.E. Turner. (2004) Postmenopausal hormone therapy before and after breast cancer: clinical experiences. Maturitas 49:1, pages S22-S31.
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Alessandra Crisafulli, Herbert Marini, Alessandra Bitto, Domenica Altavilla, Giovanni Squadrito, Adolfo Romeo, Elena B. Adamo, Rolando Marini, Rosario D'Anna, Francesco Corrado, Sebastiano Bartolone, Nicola Frisina & Francesco Squadrito. (2004) Effects of genistein on hot flushes in early postmenopausal women: a randomized, double-blind EPT- and placebo-controlled study.. Menopause 11:4, pages 400-404.
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Charlotte Atkinson, Ruth ML Warren, Evis Sala, Mitch Dowsett, Alison M Dunning, Catherine S Healey, Shirley Runswick, Nicholas E Day & Sheila A Bingham. (2004) Red clover-derived isoflavones and mammographic breast density: a double-blind, randomized, placebo-controlled trial [ISRCTN42940165]. Breast Cancer Research 6:3.
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Syed H Tariq. (2004) Herbal therapies. Clinics in Geriatric Medicine 20:2, pages 237-257.
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Joan Pitkin. (2016) Red Clover Isoflavones in Practice: A Clinician's View. British Menopause Society Journal 10:1_suppl, pages 7-12.
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Barentsen Ronald. (2016) Red clover isoflavones and menopausal health. British Menopause Society Journal 10:1_suppl, pages 4-7.
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&NA;. (2004) Treatment of menopause-associated vasomotor symptoms: position statement of The North American Menopause Society: Retracted. Menopause 11:1, pages 11-33.
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Alyson L. Huntley & Edzard Ernst. (2004) Soy for the treatment of perimenopausal symptoms—a systematic review. Maturitas 47:1, pages 1-9.
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. (2010) Disappointing results for Trifolium pratense (red clover) isoflavones in the management of menopausal symptoms. Focus on Alternative and Complementary Therapies 8:4, pages 413-414.
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Sylvie Dodin, Claudine Blanchet & Isabelle Marc. (2003) Phytoœstrogènes chez la femme ménopausée. médecine/sciences 19:10, pages 1030-1038.
Crossref
Michael J. Murray, William R. Meyer, Bruce A. Lessey, Richard H. Oi, Rebecca E. DeWire & Marc A. Fritz. (2003) Soy protein isolate with isoflavones does not prevent estradiol-induced endometrial hyperplasia in postmenopausal women: a pilot trial. Menopause 10:5, pages 456-464.
Crossref
Alyson L. Huntley & Edzard Ernst. (2003) A systematic review of herbal medicinal products for the treatment of menopausal symptoms. Menopause 10:5, pages 465-476.
Crossref
Susan R Davis. (2003) Menopause: new therapies. Medical Journal of Australia 178:12, pages 634-637.
Crossref
Colleen E. Piersen. (2016) Phytoestrogens in Botanical Dietary Supplements: Implications for Cancer. Integrative Cancer Therapies 2:2, pages 120-138.
Crossref
Eini Nikander, Annamari Kilkkinen, Merja Metsä-Heikkilä, Herman Adlercreutz, Pirjo Pietinen, Aila Tiitinen & Olavi Ylikorkala. (2003) A Randomized Placebo-Controlled Crossover Trial With Phytoestrogens in Treatment of Menopause in Breast Cancer Patients. Obstetrics & Gynecology 101:6, pages 1213-1220.
Crossref
Mindy S. Kurzer. (2003) Phytoestrogen Supplement Use by Women. The Journal of Nutrition 133:6, pages 1983S-1986S.
Crossref
Alison M Duncan, William R Phipps & Mindy S Kurzer. (2003) Phyto-oestrogens. Best Practice & Research Clinical Endocrinology & Metabolism 17:2, pages 253-271.
Crossref
Lynnette K Nieman. (2003) Management of surgically hypogonadal patients unable to take sex hormone replacement therapy. Endocrinology and Metabolism Clinics of North America 32:2, pages 325-336.
Crossref
Mark Messina & Claude Hughes. (2003) Efficacy of Soyfoods and Soybean Isoflavone Supplements for Alleviating Menopausal Symptoms Is Positively Related to Initial Hot Flush Frequency. Journal of Medicinal Food 6:1, pages 1-11.
Crossref
Sonia Davison & Susan R. Davis. (2003) Hormone replacement therapy: current controversies. Clinical Endocrinology 58:3, pages 249-261.
Crossref
Elizabeth Farrell. (2003) Medical choices available for management of menopause. Best Practice & Research Clinical Endocrinology & Metabolism 17:1, pages 1-16.
Crossref
V Beck, E Unterrieder, L Krenn, W Kubelka & A Jungbauer. (2003) Comparison of hormonal activity (estrogen, androgen and progestin) of standardized plant extracts for large scale use in hormone replacement therapy. The Journal of Steroid Biochemistry and Molecular Biology 84:2-3, pages 259-268.
Crossref
F. Milan & K. Montgomery. 2003. Alternative Medicine for the Elderly. Alternative Medicine for the Elderly 365 397 .
Kenneth D.R. Setchell, Nadine M. Brown & Eva Lydeking-Olsen. (2002) The Clinical Importance of the Metabolite Equol—A Clue to the Effectiveness of Soy and Its Isoflavones. The Journal of Nutrition 132:12, pages 3577-3584.
Crossref
W Wuttke, H Jarry, S Westphalen, V Christoffel & D Seidlová-Wuttke. (2002) Phytoestrogens for hormone replacement therapy?. The Journal of Steroid Biochemistry and Molecular Biology 83:1-5, pages 133-147.
Crossref
Delia M. Brownson, Nicolas G. Azios, Brie K. Fuqua, Su F. Dharmawardhane & Tom J. Mabry. (2002) Flavonoid Effects Relevant to Cancer. The Journal of Nutrition 132:11, pages 3482S-3489S.
Crossref
Evelyne Drapier Faure, Philippe Chantre & Pierre Mares. (2002) Effects of a standardized soy extract on hot flushes: a multicenter, double-blind, randomized, placebo-controlled study. Menopause 9:5, pages 329-334.
Crossref
Maida Taylor. (2002) Alternative medicine and the perimenopause. Obstetrics and Gynecology Clinics of North America 29:3, pages 555-573.
Crossref
Peter H.M. van de Weijer & Ronald Barentsen. (2002) Isoflavones from red clover (Promensil®) significantly reduce menopausal hot flush symptoms compared with placebo. Maturitas 42:3, pages 187-193.
Crossref
Paola Albertazzi & David W Purdie. (2002) The nature and utility of the phytoestrogens: a review of the evidence. Maturitas 42:3, pages 173-185.
Crossref
Anna Wu, Lilian Thompson, Wendy Ward, Maurice Bennink, Elizabeth Rondini, Charles Wood a, Stephen Barnes b, Mark Cline a & Andreas Constantinou. 2002. Phytoestrogens and Health. Phytoestrogens and Health.
Retha Newbold a, Wendy Jefferson a, Elizabeth Padilla-Banks a, Bill Bullock b, Barry Delclos, Thomas Badger, Martin Ronis, Reza Hakkak, Sohelia Korourian, oel Rotstein a & G Sarwar Gilani b. 2002. Phytoestrogens and Health. Phytoestrogens and Health.
Fabien Dalais, Mara Vitolins a, Mary "Anthony a,b"Gregory Burke a. 2002. Phytoestrogens and Health. Phytoestrogens and Health.
Mark Messina, Clare Hasler, Susan Kundrat & Eric Gugger. 2002. Phytoestrogens and Health. Phytoestrogens and Health.
Alyson Huntley. (2010) Complementary therapies for the relief of menopausal symptoms. Focus on Alternative and Complementary Therapies 7:2, pages 121-125.
Crossref
Ayman A.A. Ewies. (2002) Phytoestrogens in the Management of the Menopause:. Obstetrical and Gynecological Survey 57:5, pages 306-313.
Crossref
Jan Howes, Mark Waring, Li Huang & Laurence G. Howes. (2002) Long-Term Pharmacokinetics of an Extract of Isoflavones from Red Clover ( Trifolium pratense ) . The Journal of Alternative and Complementary Medicine 8:2, pages 135-142.
Crossref
Mark A Moyad. (2002) Complementary/alternative therapies for reducing hot flashes in prostate cancer patients: reevaluating the existing indirect data from studies of breast cancer and postmenopausal women. Urology 59:4, pages 20-33.
Crossref
Paola Albertazzi. (2002) Clinical use of soy products. International Congress Series 1229, pages 189-193.
Crossref
. (2002) Postmenopausal Hormone-Replacement Therapy. New England Journal of Medicine 346:1, pages 63-65.
Crossref
William R. Phipps, Alison M. Duncan & Mindy S. Kurzer. (2002) Isoflavones and Postmenopausal Women. Treatments in Endocrinology 1:5, pages 293-311.
Crossref
Susan R. Davis. 2002. Selective Estrogen Receptor Modulators. Selective Estrogen Receptor Modulators 345 363 .
MAIDA TAYLOR. (2001) Botanicals: Medicines and Menopause. Clinical Obstetrics and Gynecology 44:4, pages 853-863.
Crossref
E Ernst & C Stevinson. (2001) Herbal Medicines and Phyto-oestrogens for Menopausal Symptoms. Medicine 29:10, pages 19-24.
Crossref
Georgina E. Hale, Claude L. Hughes, Stanley J. Robboy, Sanjay K. Agarwal & Marsha Bievre. (2001) A double-blind randomized study on the effects of red clover isoflavones on the endometrium. Menopause 8:5, pages 338-346.
Crossref
Adriane Fugh-Berman & Fredi Kronenberg. (2001) Red clover (Trifolium pratense) for menopausal women: current state of knowledge. Menopause 8:5, pages 333-337.
Crossref
Phillip B. Clifton-Bligh, Rodney J. Baber, Greg R. Fulcher, Maria-Liza Nery & Terry Moreton. (2001) The effect of isoflavones extracted from red clover (Rimostil) on lipid and bone metabolism. Menopause 8:4, pages 259-265.
Crossref
Andrea R Genazzani & Marco Gambacciani. (2001) HRT in the third millennium. Maturitas 38, pages S49-S55.
Crossref
. (2000) 2. What is the role of phytoestrogens in treating menopausal symptoms?. Medical Journal of Australia 173:S4.
Crossref
Georgina Hale, Marsha Bievre & Claude Hughes. (2000) Exploring the role of progestins and phytoestrogens in menopause. Integrative Medicine 2:2-3, pages 133-141.
Crossref
Susan R. Davis. 2000. Sex Hormone Replacement Therapy. Sex Hormone Replacement Therapy 83 107 .

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