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Pharmaceutical Biology Volume 48, 2010 - Issue 7
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Research Article

Antidepressant effects of the extract YZ-50 from Polygala tenuifolia in chronic mild stress treated rats and its possible mechanisms

Yuan HuDept. of Clinical Pharmacology, Pharmacy Care Center, Chinese PLA General Hospital, Beijing, China
,
Ping LiuDept. of Clinical Pharmacology, Pharmacy Care Center, Chinese PLA General Hospital, Beijing, China
,
Dai-Hong GuoDept. of Clinical Pharmacology, Pharmacy Care Center, Chinese PLA General Hospital, Beijing, ChinaCorrespondence[email protected]
,
Khalid RahmanFaculty of Science, School of Biomolecular Sciences, Liverpool John Moores University, Byrom Street, Liverpool, UK
,
Dong-Xiao WangDept. of Clinical Pharmacology, Pharmacy Care Center, Chinese PLA General Hospital, Beijing, China
&
Ting-Ting XieDept. of Clinical Pharmacology, Pharmacy Care Center, Chinese PLA General Hospital, Beijing, China
Pages 794-800 | Received 11 Jan 2009, Accepted 21 May 2009, Published online: 30 Apr 2010

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Ping Han, Ting Han, Wei Peng & Xiao-Ru Wang. (2013) Antidepressant-like effects of essential oil and asarone, a major essential oil component from the rhizome of Acorus tatarinowii. Pharmaceutical Biology 51:5, pages 589-594.
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Qijun Chen, Tanrong Jia, Xia Wu, Xiaoqing Chen, Jiajia Wang & Yinying Ba. (2023) Polygalae Radix Oligosaccharide Esters May Relieve Depressive-like Behavior in Rats with Chronic Unpredictable Mild Stress via Modulation of Gut Microbiota. International Journal of Molecular Sciences 24:18, pages 13877.
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Xian-Zhe Dong, Dong-Xiao Wang, Tian-Yi Zhang, Xu Liu, Ping Liu & Yuan Hu. (2020) Identification of protein targets for the antidepressant effects of Kai-Xin-San in Chinese medicine using isobaric tags for relative and absolute quantitation. Neural Regeneration Research 15:2, pages 302.
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YinYing Ba, MengLin Wang, KunFeng Zhang, QiJun Chen, JiaJia Wang, Hang Lv, YanYan Jiang & Renbing Shi. (2019) Intestinal Absorption Profile of Three Polygala Oligosaccharide Esters in Polygalae Radix and the Effects of Other Components in Polygalae Radix on Their Absorption. Evidence-Based Complementary and Alternative Medicine 2019, pages 1-12.
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Xiao Chun Peng, Jiang Rong Huang, Si Wei Wang, Lian Liu, Zhen Zhen Liu, Gautam Sethi, Bo Xu Ren & Feng Ru Tang. (2018) Traditional Chinese Medicine in Neuroprotection after Brain Insults with Special Reference to Radioprotection. Evidence-Based Complementary and Alternative Medicine 2018, pages 1-14.
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Ryota Araki, Hironori Fujiwara, Kinzo Matsumoto, Kazufumi Toume & Takeshi Yabe. (2018) Polygalae radix extract ameliorates behavioral and neuromorphological abnormalities in chronic corticosterone-treated mice. Traditional & Kampo Medicine 5:2, pages 89-97.
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Marzieh Sarbandi Farahani, Roodabeh Bahramsoltani, Mohammad Hosein Farzaei, Mohammad Abdollahi & Roja Rahimi. (2015) Plant-derived natural medicines for the management of depression: an overview of mechanisms of action. Reviews in the Neurosciences 26:3.
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Matthew N. Hill, Kim G.C. Hellemans, Pamela Verma, Boris B. Gorzalka & Joanne Weinberg. (2012) Neurobiology of chronic mild stress: Parallels to major depression. Neuroscience & Biobehavioral Reviews 36:9, pages 2085-2117.
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Yun Ling, Bin Wu, Ke Wang, Huihui Liu, Luying Chen, Mingsong Fan, Zhaolin Sun & Chenggang Huang. (2011) In vivo metabolism study of polygalic acid in rat using HPLC‐ESI‐MS n . Biomedical Chromatography 26:2, pages 220-224.
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