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Xin Zhao, Baoxin Xu, Peng Wu, Pan Zhao, Changchuan Guo, Yueli Cui, Yanxue Zhang, Xuelan Zhang & Huifen Li. (2020) UHPLC-MS/MS method for pharmacokinetic and bioavailability determination of five bioactive components in raw and various processed products of Polygala tenuifolia in rat plasma. Pharmaceutical Biology 58:1, pages 969-978.
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Akash Garg, Rutvi Agrawal & Rohitas Deshmukh. (2023) Pharmacology of Polygala tenuifolia and Its Significance in Traditional Chinese Medicine. Pharmacological Research - Modern Chinese Medicine, pages 100341.
Crossref
Crossref
Haoran WANG, Yanqiu GU, Rahman KHALID, Xiaofei CHEN & Ting HAN. (2023) Herbal medicines for insomnia through regulating 5-hydroxytryptamine receptors: a systematic review. Chinese Journal of Natural Medicines 21:7, pages 483-498.
Crossref
Crossref
Li Zhang, Yuan-Yuan Yong, Lan Deng, Jing Wang, Betty Yuen-Kwan Law, Meng-Ling Hu, Jian-Ming Wu, Lu Yu, Vincent Kam-Wai Wong, Chong-Lin Yu, Da-Lian Qin, Xiao-Gang Zhou & An-Guo Wu. (2023) Therapeutic potential of Polygala saponins in neurological diseases. Phytomedicine 108, pages 154483.
Crossref
Crossref
So-Ri Son, Young-Seo Yoon, Joon-Pyo Hong, Jae-Min Kim, Kyung-Tae Lee & Dae Sik Jang. (2022) Chemical Constituents of the Roots of Polygala tenuifolia and Their Anti-Inflammatory Effects. Plants 11:23, pages 3307.
Crossref
Crossref
N. Yu. Lotosh, A. V. Kryuchkova, E. A. Kulikov, I. S. Kulikova, A. A. Selishcheva, D. P. Ogurtsov, S. A. Krynsky & I. K. Malashenkova. (2022) Effect of Nanoemulsions Containing Astaxanthin or Its Esters on the Spatial Behavior of 5XFAD Mice. Nanobiotechnology Reports 17:2, pages 227-234.
Crossref
Crossref
Chun-Yan Shen, Xiao-Yi Li, Pan-Yu Ma, Hong-Lei Li, Bing Xiao, Wei-Feng Cai & Xue-Feng Xing. (2022) Nicotinamide mononucleotide (NMN) and NMN-rich product supplementation alleviate p-chlorophenylalanine-induced sleep disorders. Journal of Functional Foods 91, pages 105031.
Crossref
Crossref
Ayşe Ünlü, Kerem Teralı, Zübeyde Uğurlu Aydın, Ali A. Dönmez, Hasan Soliman Yusufoğlu & İhsan Çalış. (2022) Isolation, Characterization and In Silico Studies of Secondary Metabolites from the Whole Plant of Polygala inexpectata Peşmen & Erik. Molecules 27:3, pages 684.
Crossref
Crossref
Ning Jiang, Shanshan Wei, Yiwen Zhang, Wenlu He, Haiyue Pei, Hong Huang, Qiong Wang & Xinmin Liu. (2021) Protective Effects and Mechanism of Radix Polygalae Against Neurological Diseases as Well as Effective Substance. Frontiers in Psychiatry 12.
Crossref
Crossref
S.M. Moazzem Hossen, Mohammad Akramul Hoque Tanim, Mohammad Shahadat Hossain, Saad Ahmed Sami & Nazim Uddin Emon. (2021) Deciphering the CNS anti-depressant, antioxidant and cytotoxic profiling of methanol and aqueous extracts of Trametes versicolor and molecular interactions of its phenolic compounds. Saudi Journal of Biological Sciences 28:11, pages 6375-6383.
Crossref
Crossref
Ying-Jie Dong, Ning-Hua Jiang, Liang-Hui Zhan, Xi Teng, Xi Fang, Min-Qiu Lin, Zhi-Yi Xie, Rong Luo, Lin-Zi Li, Bo Li, Bei-Bei Zhang, Gui-Yuan Lv & Su-Hong Chen. (2021) Soporific effect of modified Suanzaoren Decoction on mice models of insomnia by regulating Orexin-A and HPA axis homeostasis. Biomedicine & Pharmacotherapy 143, pages 112141.
Crossref
Crossref
Diem Ngoc Hong Tran, I-Hsuan Hwang, Fun-Jou Chen, Yuan-Pu Tseng, Ching-Mao Chang, Shih-Jen Tsai, Jen-Lin Yang, Ta-Peng Wu, Chung-Hua Hsu, Fang-Pey Chen & Yen-Ying Kung. (2021) Core prescription pattern of Chinese herbal medicine for depressive disorders in Taiwan: A nationwide population-based study. Integrative Medicine Research 10:3, pages 100707.
Crossref
Crossref
Wu Zeng, An Guo Wu, Xiao-Gang Zhou, Imran Khan, Rui Long Zhang, Hang Hong Lo, Li Qun Qu, Lin Lin Song, Xiao Yun Yun, Hui Miao Wang, Juan Chen, Jerome P.L. Ng, Fang Ren, Si Yu Yuan, Lu Yu, Yong Tang, Guo Xin Huang, Vincent Kam Wai Wong, Sookja Kim Chung, Simon Wing Fai Mok, Da Lian Qin, Hua Lin Sun, Liang Liu, W.L. Wendy Hsiao & Betty Yuen Kwan Law. (2021) Saponins isolated from Radix polygalae extent lifespan by modulating complement C3 and gut microbiota. Pharmacological Research 170, pages 105697.
Crossref
Crossref
Dan-Tong Zhao, Yi-Jun Gao, Wen-Jin Zhang, Tian-Chen Bi, Xiao Wang, Chun-Xia Ma & Rong Rong. (2021) Development a multi-immunoaffinity column LC-MS-MS method for comprehensive investigation of mycotoxins contamination and co-occurrence in traditional Chinese medicinal materials. Journal of Chromatography B 1178, pages 122730.
Crossref
Crossref
Yueli Cui, Xin Zhao, Yuqiu Tang, Yanxue Zhang, Le Sun & Xuelan Zhang. (2021) Comparative Study on the Chemical Components and Gastrointestinal Function on Rats of the Raw Product and Licorice-Simmered Product of Polygala tenuifolia. Evidence-Based Complementary and Alternative Medicine 2021, pages 1-14.
Crossref
Crossref
Mohamed A. Salem, Ahmed Zayed & Shahira M. Ezzat. 2021. Phytochemistry, the Military and Health. Phytochemistry, the Military and Health
121
150
.
Md. Arfin Ibn Aziz, Niloy Barua, Abu Montakim Tareq, Najmul Alam, Ranak Jahan Prova, Miskatun Nur Mamun, Mohammed Aktar Sayeed, Md. Ashraf Uddin Chowdhury & Talha Bin Emran. (2020) Possible neuropharmacological effects of Adenia trilobata (Roxb.) in the Swiss albino mice model. Future Journal of Pharmaceutical Sciences 6:1.
Crossref
Crossref
Muqeet Wahid, Anam Ali, Fatima Saqib, Ambreen Aleem, Sumbal Bibi, Khurram Afzal, Atif Ali, Ayesha Baig, Shujaat Ali Khan & Muhammad Hassham Hassan Bin Asad. (2020) Pharmacological exploration of traditional plants for the treatment of neurodegenerative disorders. Phytotherapy Research 34:12, pages 3089-3112.
Crossref
Crossref
Xiao-juan Ren, Guan-ying Wang, Xing-ping Zhang, Qing-quan Wang & Zhi-peng Peng. (2020) Sedative and Hypnotic Effects and Transcriptome Analysis of Polygala tenuifolia in Aged Insomnia Rats. Chinese Journal of Integrative Medicine 26:6, pages 434-441.
Crossref
Crossref
Zi‑Wen Chen, Chao‑Bao Peng, Zhong Pei, Meng‑Ruo Zhang, Tian‑Chan Yun, Zhi‑Min Yang & Fu‑Ping Xu. (2020) Effects of tenuifolin on rest/wake behaviour in zebrafish. Experimental and Therapeutic Medicine.
Crossref
Crossref
Yufei Sun, Guifang Feng, Yan Zheng, Shu Liu, Yan Zhang, Zifeng Pi, Fengrui Song & Zhiqiang Liu. (2020) Putative multiple reaction monitoring strategy for the comparative pharmacokinetics of postoral administration Renshen–Yuanzhi compatibility through liquid chromatography–tandem mass spectrometry. Journal of Ginseng Research 44:1, pages 105-114.
Crossref
Crossref
Vinicius M. Gadotti & Gerald W. Zamponi. (2019) Anxiolytic effects of the flavonoid luteolin in a mouse model of acute colitis. Molecular Brain 12:1.
Crossref
Crossref
YinYing Ba, MengLin Wang, KunFeng Zhang, QiJun Chen, JiaJia Wang, Hang Lv, YanYan Jiang & Renbing Shi. (2019) Intestinal Absorption Profile of Three Polygala Oligosaccharide Esters in Polygalae Radix and the Effects of Other Components in Polygalae Radix on Their Absorption. Evidence-Based Complementary and Alternative Medicine 2019, pages 1-12.
Crossref
Crossref
Zefeng Zhao, Yajun Bai, Jing Xie, Xufei Chen, Xirui He, Ying Sun, Yujun Bai, Yangyang Zhang, Shaoping Wu & Xiaohui Zheng. (2019) Excavating precursors from the traditional Chinese herb Polygala tenuifolia and Gastrodia elata: Synthesis, anticonvulsant activity evaluation of 3,4,5-trimethoxycinnamic acid (TMCA) ester derivatives. Bioorganic Chemistry 88, pages 102832.
Crossref
Crossref
Vijay Kumar, Preeti Gupta & Md. Imtaiyaz Hassan. (2019) Mechanism and implications of traditional Chinese medicine in amyotrophic lateral sclerosis therapy. Journal of Proteins and Proteomics.
Crossref
Crossref
Cheol Hyoung Park, Pil-Soon Yang, Yeo Sang Yoon & Jeong-Chan Ra. (2019) Study on the safety of Polygala tenuifolia Willdenow root extract powder (BT-11) in young person aged from 9 to 19 years old. Journal of Ethnopharmacology 232, pages 119-129.
Crossref
Crossref
Baoxin Xu, Congcong Qu, Wenhua Zheng, Yaya Xi, Xin Zhao, Huifen Li, Jiangting Liu & Xuelan Zhang. (2018) UHPLC-MS/MS method for simultaneous determination of Radix Polygalae glycolipids and organic acids in rat plasma and application in a pharmacokinetic study. Journal of Chromatography B 1100-1101, pages 165-173.
Crossref
Crossref
Ju-Yeon Shin, Jung-Won Shin, Sang-Kyu Ha, Yoorim Kim, Kelley M. Swanberg, Suck Lee, Tae-Woo Kim & Sungho Maeng. (2018)
Radix Polygalae
Extract Attenuates PTSD-like Symptoms in a Mouse Model of Single Prolonged Stress and Conditioned Fear Possibly by Reversing BAG1
. Experimental Neurobiology 27:3, pages 200-209.
Crossref
Crossref
Sheng Wang, Lin-lin Zhao, Xin-jian Qiu, Dong-sheng Wang, Tao Tang, Jie-kun Luo, Sui-yu Hu & Hui-yong Huang. (2018) Efficacy and Safety of a Formulated Herbal Granula, Jiu Wei Zhen Xin, for Generalized Anxiety Disorder: A Meta-Analysis. Evidence-Based Complementary and Alternative Medicine 2018, pages 1-12.
Crossref
Crossref
Julia Fedotova, Peter Kubatka, Dietrich Büsselberg, Alexander G. Shleikin, Martin Caprnda, Jozef Dragasek, Luis Rodrigo, Miroslav Pohanka, Iveta Gasparova, Vladimir Nosal, Radka Opatrilova, Tawar Qaradakhi, Anthony Zulli & Peter Kruzliak. (2017) Therapeutical strategies for anxiety and anxiety-like disorders using plant-derived natural compounds and plant extracts. Biomedicine & Pharmacotherapy 95, pages 437-446.
Crossref
Crossref
Juan Li, Dan-Dan Wang, Xiao-Shuang Xu, Lu Bai, Bing Peng, Ya-Jie Pu, Hong-Ling Tian, Xue-Mei Qin, Fu-Sheng Zhang & Cun-Gen Ma. (2017)
Utilization of UPLC/Q-TOF-MS-Based Metabolomics and AFLP-Based Marker-Assisted Selection to Facilitate/Assist Conventional Breeding of
Polygala tenuifolia
. Chemistry & Biodiversity 14:9, pages e1700163.
Crossref
Crossref
Jung-Won Shin, Hyunwoo Park, Yoonju Cho, Suck Lee, Jiwon Yoon & Sungho Maeng. (2017) Reduced Consolidation, Reinstatement, and Renewal of Conditioned Fear Memory by Repetitive Treatment of Radix Polygalae in Mice. Frontiers in Psychiatry 8.
Crossref
Crossref
Anna J Hyde, Brian H May, Lin Dong, Mei Feng, Shaonan Liu, Xinfeng Guo, Anthony Lin Zhang, Chuanjian Lu & Charlie Changli Xue. (2016) Herbal medicine for management of the behavioural and psychological symptoms of dementia (BPSD): A systematic review and meta-analysis. Journal of Psychopharmacology 31:2, pages 169-183.
Crossref
Crossref
Amrinder Singh & Kaicun Zhao. 2017. Neurobiology of Chinese Herb Medicine. Neurobiology of Chinese Herb Medicine
97
115
.
Qing Cao, Yong Jiang, Su-Ying Cui, Peng-Fei Tu, Yue-Mei Chen, Xiao-Li Ma, Xiang-Yu Cui, Yuan-Li Huang, Hui Ding, Jin-Zhi Song, Bin Yu, Zhao-Fu Sheng, Zi-Jun Wang, Ya-Ping Xu, Guang Yang, Hui Ye, Xiao Hu & Yong-He Zhang. (2016) Tenuifolin, a saponin derived from Radix Polygalae, exhibits sleep-enhancing effects in mice. Phytomedicine 23:14, pages 1797-1805.
Crossref
Crossref
Yuan Hu, Yu-Nin Wang, Gang-Qiang Zhang, Xian-Zhe Dong, Wan-Wan Liu & Ping Liu. (2016) Gan-Dan-Liang-Yi-Tang alleviates p-chlorophenylalanine-induced insomnia through modification of the serotonergic and immune system. Experimental and Therapeutic Medicine 12:5, pages 3087-3092.
Crossref
Crossref
Farhan Mohammad, Joses Ho, Jia Hern Woo, Chun Lei Lim, Dennis Jun Jie Poon, Bhumika Lamba & Adam Claridge-Chang. (2016) Concordance and incongruence in preclinical anxiety models: Systematic review and meta-analyses. Neuroscience & Biobehavioral Reviews 68, pages 504-529.
Crossref
Crossref
Betty Law, Simon Mok, An Wu, Christopher Lam, Margaret Yu & Vincent Wong. (2016) New Potential Pharmacological Functions of Chinese Herbal Medicines via Regulation of Autophagy. Molecules 21:3, pages 359.
Crossref
Crossref
An-Guo Wu, Vincent Kam-Wai Wong, Wu Zeng, Liang Liu & Betty Yuen-Kwan Law. (2015) Identification of novel autophagic Radix Polygalae fraction by cell membrane chromatography and UHPLC-(Q)TOF-MS for degradation of neurodegenerative disease proteins. Scientific Reports 5:1.
Crossref
Crossref
Qiyuan Shi, Jiale Chen, Qinfen Zhou, Houliang Lei, Lianjun Luan, Xuesong Liu & Yongjiang Wu. (2015) Indirect identification of antioxidants in Polygalae Radix through their reaction with 2,2-diphenyl-1-picrylhydrazyl and subsequent HPLC–ESI-Q-TOF-MS/MS. Talanta 144, pages 830-835.
Crossref
Crossref
Qiyuan Shi, Shu Geng, Jiale Chen, Qinfen Zhou, Ye Jin, Houliang Lei, Lianjun Luan, Xuesong Liu & Yongjiang Wu. (2015) An efficient procedure for preparing main acylated pentasaccharides from Polygalae Radix using integrated extraction–adsorption method followed by semi-preparative high performance liquid chromatography. Separation and Purification Technology 153, pages 84-90.
Crossref
Crossref
Hongling Tian, Xiaoshuang Xu, Fusheng Zhang, Yaoqin Wang, Shuhong Guo, Xuemei Qin & Guanhua Du. (2015)
Analysis of
Polygala tenuifolia
Transcriptome and Description of Secondary Metabolite Biosynthetic Pathways by Illumina Sequencing
. International Journal of Genomics 2015, pages 1-11.
Crossref
Crossref
Xiao-Bo Yu, Guang-Lu Liu, Bin Zhu, Kai Hao, Fei Ling & Gao-Xue Wang. (2014) In vitro immunocompetence of two compounds isolated from Polygala tenuifolia and development of resistance against grass carp reovirus (GCRV) and Dactylogyrus intermedius in respective host. Fish & Shellfish Immunology 41:2, pages 541-548.
Crossref
Crossref
Yong-Jiang Wu, Qi-Yuan Shi, Hou-Liang Lei, Ye Jin, Xue-Song Liu & Lian-Jun Luan. (2014) Simple and efficient preparation of 3,6′-disinapoylsucrose from Polygalae Radix via column chromatographic extraction and reversed-phase flash chromatography. Separation and Purification Technology 135, pages 7-13.
Crossref
Crossref
Fusheng Zhang, Xiaowei Li, Zhenyu Li, Xiaoshuang Xu, Bing Peng, Xuemei Qin & Guanhua Du. (2014) UPLC/Q-TOF MS-Based Metabolomics and qRT-PCR in Enzyme Gene Screening with Key Role in Triterpenoid Saponin Biosynthesis of Polygala tenuifolia. PLoS ONE 9:8, pages e105765.
Crossref
Crossref
Chung-Il Lee, Jin-Yi Han, Jin Tae Hong & Ki-Wan Oh. (2013) 3,4,5-Trimethoxycinnamic acid (TMCA), one of the constituents of Polygalae Radix enhances pentobarbital-induced sleeping behaviors via GABAAergic systems in mice. Archives of Pharmacal Research 36:10, pages 1244-1251.
Crossref
Crossref
Zhenghang ZhaoMinfeng Fang, Dandan Xiao, Mei Liu, Nadezhda FefelovaChen Huang, Wei-Jin Zang & Lai-Hua Xie. (2013) Potential Antiarrhythmic Effect of Methyl 3,4,5-Trimethoxycinnamate, a Bioactive Substance from Roots of <i>Polygalae Radix</i>: Suppression of Triggered Activities in Rabbit Myocytes. Biological & Pharmaceutical Bulletin Biological and Pharmaceutical Bulletin 36:2, pages 238-244.
Crossref
Crossref
Yue-Lin Song, Ke-Wu Zeng, Tian-Xing Shi, Yong Jiang & Peng-Fei Tu. (2013) Sibiricasaponins A–E, five new triterpenoid saponins from the aerial parts of Polygala sibirica L.. Fitoterapia 84, pages 295-301.
Crossref
Crossref
Marie-Aleth Lacaille-Dubois, Clément Delaude & Anne-Claire Mitaine-Offer. 2013. Natural Products. Natural Products
3205
3223
.
Hong Zhang, Ting Han, Cheng-Hao Yu, Yi-Ping Jiang, Cheng Peng, Xia Ran & Lu-Ping Qin. (2012) Analysis of the chemical composition, acute toxicity and skin sensitivity of essential oil from rhizomes of Ligusticum chuanxiong. Journal of Ethnopharmacology 144:3, pages 791-796.
Crossref
Crossref
Yun Ling, Bin Wu, Ke Wang, Huihui Liu, Luying Chen, Mingsong Fan, Zhaolin Sun & Chenggang Huang. (2011)
In vivo
metabolism study of polygalic acid in rat using HPLC‐ESI‐MS
n
. Biomedical Chromatography 26:2, pages 220-224.
Crossref
Crossref