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Pharmaceutical Biology Volume 49, 2011 - Issue 9
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Research Article

Chemopreventive effects of wild carrot oil against 7,12-dimethyl benz(a)anthracene-induced squamous cell carcinoma in mice

Rami Abu ZeinabDepartment of Natural Sciences, School of Arts and Sciences, Lebanese American University, Byblos, Lebanon
,
Mohamad MrouehSchool of Pharmacy, Lebanese American University, Byblos, Lebanon
,
Mona Diab-AssafFaculty of Sciences, Lebanese University, Fanar, Beirut, Lebanon
,
Abdo JurjusSchool of Medicine, American University of Beirut, Beirut, Lebanon
,
Brigitte WexDepartment of Natural Sciences, School of Arts and Sciences, Lebanese American University, Byblos, Lebanon
,
Amer SakrAnalytical Testing Laboratories, Achrafieh, Beirut, Lebanon
&
Costantine F. DaherDepartment of Natural Sciences, School of Arts and Sciences, Lebanese American University, Byblos, LebanonCorrespondence[email protected]
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Pages 955-961 | Received 26 Aug 2010, Accepted 17 Jan 2011, Published online: 21 Jul 2011

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Wassim N. Shebaby, Costantine F. Daher, Mirvat El-Sibai, Kikki Bodman-Smith, Anthony Mansour, Marc C. Karam & Mohamad Mroueh. (2015) Antioxidant and hepatoprotective activities of the oil fractions from wild carrot (Daucus carota ssp. carota). Pharmaceutical Biology 53:9, pages 1285-1294.
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Articles from other publishers (22)

Mohammed Ajjoun, Loubna Kharchoufa, Ilyass Alami Merrouni & Mostafa Elachouri. (2022) Moroccan medicinal plants traditionally used for the treatment of skin diseases: From ethnobotany to clinical trials. Journal of Ethnopharmacology 297, pages 115532.
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Alicja Kowalczyk, Robert Kupczyński, Elżbieta Gałęska, Jose P. Araujo & Ewa Czerniawska-Piątkowska. (2022) Clinical Application of Bioextracts in Supporting the Reproductive System of Animals and Humans: Potential and Limitations. Evidence-Based Complementary and Alternative Medicine 2022, pages 1-12.
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Leila Jaafar, Zeinab Chamseddine & Mirvat El-Sibai. (2020) StarD13: a potential star target for tumor therapeutics. Human Cell 33:3, pages 437-443.
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Wassim Shebaby, Andree Elias, Mohamad Mroueh, Bilal Nehme, Nahia Dib El Jalbout, Rita Iskandar, Joey C. Daher, Michelle Zgheib, Pascale Ibrahim, Vanessa Dwairi, Jean Michel Saad, Robin I. Taleb & Costantine F. Daher. (2020) Himachalol induces apoptosis in B16-F10 murine melanoma cells and protects against skin carcinogenesis. Journal of Ethnopharmacology 253, pages 112545.
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Timothy Omara, Ambrose K. Kiprop, Rose C. Ramkat, Jackson Cherutoi, Sarah Kagoya, Decrah Moraa Nyangena, Tsedey Azeze Tebo, Papias Nteziyaremye, Lucy Nyambura Karanja, Abigael Jepchirchir, Alfayo Maiyo, Betty Jematia Kiptui, Immaculate Mbabazi, Caroline Kiwanuka Nakiguli, Brenda Victoria Nakabuye & Margaret Chepkemoi Koske. (2020) Medicinal Plants Used in Traditional Management of Cancer in Uganda: A Review of Ethnobotanical Surveys, Phytochemistry, and Anticancer Studies. Evidence-Based Complementary and Alternative Medicine 2020, pages 1-26.
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Vanja Šeregelj, Jelena Vulić, Gordana Ćetković, Jasna Čanadanovć-Brunet, Vesna Tumbas Šaponjac & Slađana Stajčić. 2020. Bioactive Natural Products. Bioactive Natural Products 307 344 .
Tarun Kumar Dua & Paramita Paul. 2020. Plant-derived Bioactives. Plant-derived Bioactives 549 569 .
Hamid E. Daaboul, Carole Dagher, Robin I. Taleb, Kikki Bodman-Smith, Wassim N. Shebaby, Mirvat El-Sibai, Mohamad A. Mroueh & Costantine F. Daher. (2019) β-2-Himachalen-6-ol inhibits 4T1 cells-induced metastatic triple negative breast carcinoma in murine model. Chemico-Biological Interactions 309, pages 108703.
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Hamid E. Daaboul, Carole Dagher, Robin I. Taleb, Kikki Bodman-Smith, Wassim N. Shebaby, Mirvat El-Sibai, Mohamad A. Mroueh & Costantine F. Daher. (2018) The chemotherapeutic effect of β-2-himachalen-6-ol in chemically induced skin tumorigenesis. Biomedicine & Pharmacotherapy 103, pages 443-452.
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Arpita Roy, Nupur Jauhari & Navneeta Bharadvaja. 2018. Anticancer Plants: Natural Products and Biotechnological Implements. Anticancer Plants: Natural Products and Biotechnological Implements 109 139 .
Wassim N Shebaby, Mohamad A Mroueh, Petra Boukamp, Robin I Taleb, Kikki Bodman-Smith, Mirvat El-Sibai & Costantine F Daher. (2017) Wild carrot pentane-based fractions suppress proliferation of human HaCaT keratinocytes and protect against chemically-induced skin cancer. BMC Complementary and Alternative Medicine 17:1.
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Hamid E Daaboul, Costantine F Daher, Robin I Taleb, Joelle Boulos, Kikki Bodman-Smith, Petra Boukamp, Wassim N Shebaby, Carol Dagher, Mirvat El-Sibai & Mohamad A Mroueh. (2017) β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo . Journal of Pharmacy and Pharmacology 69:11, pages 1552-1564.
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Hamid E. Daaboul, Costantine F. Daher, Kikki Bodman-Smith, Robin I. Taleb, Wassim N. Shebaby, Joelle Boulos, Carole Dagher, Mohamad A. Mroueh & Mirvat El-Sibai. (2017) Antitumor activity of β-2-himachalen-6-ol in colon cancer is mediated through its inhibition of the PI3K and MAPK pathways. Chemico-Biological Interactions 275, pages 162-170.
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S. Higgins, K. A. Miller, K. Y. Wojcik, O. Ahadiat, L. A. Escobedo, A. Wysong & M. Cockburn. (2017) Phytochemicals and Naturally Occurring Substances in the Chemoprevention of Skin Cancer. Current Dermatology Reports 6:3, pages 196-203.
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Robin I. Taleb, Paul Najm, Wassim Shebaby, Joelle C. Boulos, Sally Demirdjian, Essa Hariri, Mirvat El-Sibai, Costantine Daher & Mohamad Mroueh. (2016) β-2-himachalen-6-ol: A novel anticancer sesquiterpene unique to the Lebanese wild carrot. Journal of Ethnopharmacology 190, pages 59-67.
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Nor Hazwani Mohd Ariffin & Rosnani Hasham. (2016) Potential dermatological application on Asian plants. Biotechnology and Bioprocess Engineering 21:3, pages 337-354.
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Wassim N. ShebabyK.B. Bodman-SmithAnthony MansourMohamad MrouehRobin I. TalebMirvat El-SibaiCostantine F. Daher. (2015) Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways . Journal of Medicinal Food 18:7, pages 745-752.
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Mirna Tawil, Amira Bekdash, Mohammad Mroueh, Costantine F. Daher & Ralph J. Abi-Habib. (2015) Wild Carrot Oil Extract is Selectively Cytotoxic to Human Acute Myeloid Leukemia Cells. Asian Pacific Journal of Cancer Prevention 16:2, pages 761-767.
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T. K. LimT. K. Lim. 2015. Edible Medicinal and Non Medicinal Plants. Edible Medicinal and Non Medicinal Plants 374 416 .
Wassim N Shebaby, Mohammad Mroueh, Kikki Bodman-Smith, Anthony Mansour, Robin I Taleb, Costantine F Daher & Mirvat El-Sibai. (2014) Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells. BMC Complementary and Alternative Medicine 14:1.
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Perla Zgheib, Costantine F. Daher, Mohamad Mroueh, Anita Nasrallah, Robin I. Taleb & Mirvat El-Sibai. (2014) <b><i>Daucus carota</i></b> Pentane/Diethyl Ether Fraction Inhibits Motility and Reduces Invasion of Cancer Cells. Chemotherapy 60:5-6, pages 302-309.
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Wassim Nasri Shebaby, Mirvat El-Sibai, Kikki Bodman- Smith, Marc Christoph Karam, Mohamad Mroueh & Costantine F. Daher. (2013) The Antioxidant and Anticancer Effects of Wild Carrot Oil Extract. Phytotherapy Research 27:5, pages 737-744.
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