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Research Article

Oleanolic acid induces apoptosis of MKN28 cells via AKT and JNK signaling pathways

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Pages 789-795 | Received 26 May 2013, Accepted 07 Nov 2013, Published online: 07 Feb 2014

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Zhiqi Shi, Shugang Pan, Luolin Wang & Sha Li. (2021) Oleanolic Acid Attenuates Morphine Withdrawal Symptoms in Rodents: Association with Regulation of Dopamine Function. Drug Design, Development and Therapy 15, pages 3685-3696.
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Huai-Feng Li, Xu-An Wang, Shan-Shan Xiang, Yun-Ping Hu, Lin Jiang, Yi-Jun Shu, Mao-Lan Li, Xiang-Song Wu, Fei Zhang, Yuan-Yuan Ye, Hao Weng, Run-Fa Bao, Yang Cao, Wei Lu, Qian Dong & Ying-Bin Liu. (2015) Oleanolic acid induces mitochondrial-dependent apoptosis and G0/G1 phase arrest in gallbladder cancer cells. Drug Design, Development and Therapy 9, pages 3017-3030.
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Articles from other publishers (19)

Yile Liao, Yu Gui, Qingzhou Li, Jun An & Dong Wang. (2023) The signaling pathways and targets of natural products from traditional Chinese medicine treating gastric cancer provide new candidate therapeutic strategies. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1878:6, pages 188998.
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Ying Kong, Periyannan Velu, Annamalai Vijayalakshmi & Chao Yuan. (2023) Green Synthesis of Magnetic Nanoparticles from Oldenlandia diffusa : Characterization and Therapeutic Activities . Journal of Biomedical Nanotechnology 19:8, pages 1337-1345.
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Ammara Riaz, Azhar Rasul, Rabia Batool, Lubna Kanwal, Ghulam Hussain, Iqra Sarfraz, Muhammad Ajmal Shah, Faiza Rao, Ilknur Ucak, Sevki Adem & Marwa A.A. Fayed. 2023. Phytonutrients in the Treatment of Gastrointestinal Cancer. Phytonutrients in the Treatment of Gastrointestinal Cancer 182 208 .
Maoyuan Zhao, Yi Yang, Qing Nian, Caifei Shen, Xiaolin Xiao, Wenhao Liao, Qiao Zheng, Gang Zhang, Nianzhi Chen, Daoyin Gong, Jianyuan Tang, Yueqiang Wen & Jinhao Zeng. (2023) Phytochemicals and mitochondria: Therapeutic allies against gastric cancer. Phytomedicine 110, pages 154608.
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Kun Wang, Qinyue Lu, Xiang Cao, Yuhao Wang, Yanni Wu, Zhi Chen & Zhangping Yang. (2022) Application and Development of Natural Plant Metabolite Oleanolic Acid in the Nano Era. Agriculture 12:12, pages 2142.
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Elham Patrad, Solmaz Khalighfard, Taghi Amiriani, Vahid Khori & Ali Mohammad Alizadeh. (2022) Molecular mechanisms underlying the action of carcinogens in gastric cancer with a glimpse into targeted therapy. Cellular Oncology 45:6, pages 1073-1117.
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Xian-Zhe Dong, Yan Song, Yu-Pan Lu, Yuan Hu, Ping Liu & Lan Zhang. (2019) Sanguinarine inhibits the proliferation of BGC-823 gastric cancer cells via regulating miR-96-5p/miR-29c-3p and the MAPK/JNK signaling pathway. Journal of Natural Medicines 73:4, pages 777-788.
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Bin Liu, Lixia Liu, Aimin Zang, Zizheng Song, Hua Yang, Zhiyu Wang, Yanhong Shang, Tao Ma & Yonggang Zhang. (2019) Tanshinone IIA inhibits proliferation and induces apoptosis of human nasopharyngeal carcinoma cells via p53‑cyclin B1/CDC2. Oncology Letters.
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Rui Wang, Wei Yang, Yiqing Fan, Wim Dehaen, Yang Li, Huijing Li, Wei Wang, Qingxuan Zheng & Qiyong Huai. (2019) Design and synthesis of the novel oleanolic acid-cinnamic acid ester derivatives and glycyrrhetinic acid-cinnamic acid ester derivatives with cytotoxic properties. Bioorganic Chemistry 88, pages 102951.
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Jun Zhou, Yu Wang, Yiming Liu, Hanjiang Zeng, Hanshi Xu & Fan Lian. (2018) Adipose derived mesenchymal stem cells alleviated osteoarthritis and chondrocyte apoptosis through autophagy inducing. Journal of Cellular Biochemistry 120:2, pages 2198-2212.
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Mateusz Pięt & Roman Paduch. (2018) Ursolic and Oleanolic Acids as Potential Anticancer Agents Acting in the Gastrointestinal Tract. Mini-Reviews in Organic Chemistry 16:1, pages 78-91.
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Gyeong-Ji Kim, Hyeon-Ju Jo, Kwon-Jai Lee, Jeong Woo Choi & Jeung Hee An. (2018) Oleanolic acid induces p53-dependent apoptosis via the ERK/JNK/AKT pathway in cancer cell lines in prostatic cancer xenografts in mice . Oncotarget 9:41, pages 26370-26386.
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M. Twardziok, D. Meierhofer, S. Börno, B. Timmermann, S. Jäger, Sengül Boral, A. Eggert, C. I. Delebinski & G. Seifert. (2017) Transcriptomic and proteomic insight into the effects of a defined European mistletoe extract in Ewing sarcoma cells reveals cellular stress responses. BMC Complementary and Alternative Medicine 17:1.
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Bu-gao Zhou, Hai-mei Zhao, Xiu-yun Lu, Xin Wang, Yong Zou, Rong Xu, Hai-yang Yue, Yi Liu, Zheng-yun Zuo & Duan-yong Liu. (2017) Erzhi Pill® Repairs Experimental Liver Injury via TSC/mTOR Signaling Pathway Inhibiting Excessive Apoptosis. Evidence-Based Complementary and Alternative Medicine 2017, pages 1-15.
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Li Xiao Rui, Song Yu Shu, Wu Jing Jun, Chen Zi Mo, Sun Zheng Wu, Liu Shu Min, Lin Yuan, Peng Jin Yong, Song Zhi Cheng, Wang Shi Sheng & Tang Ze Yao. (2015) The dual induction of apoptosis and autophagy by SZC014, a synthetic oleanolic acid derivative, in gastric cancer cells via NF-κB pathway. Tumor Biology 37:4, pages 5133-5144.
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Byung Joo Kim, Soojin Lee, Ji Hwan Shim, Huijin Gim & Hyun Soo Park. (2016) Ethanol Extract of Oldenlandia diffusa – an Effective Chemotherapeutic for the Treatment of Colorectal Cancer in Humans. Journal of Pharmacopuncture 19:1, pages 51-58.
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Alak Manna, Subrata Chattopadhyay & Mitali Chatterjee. 2016. 81 129 .
Yun-Young Sunwoo, Jin-Hee Lee, Ho Yong Jung, Yu Jin Jung, Moon-Seo Park, Yong-An Chung, Lee-So Maeng, Young-Min Han, Hak Soo Shin, Jisoo Lee & Sang In Park. (2015) Oldenlandia diffusa Promotes Antiproliferative and Apoptotic Effects in a Rat Hepatocellular Carcinoma with Liver Cirrhosis . Evidence-Based Complementary and Alternative Medicine 2015, pages 1-11.
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Se Jin Park, Younghwa Lee, Hee Kyong Oh, Hyung Eun Lee, Younghwan Lee, Sang Yoon Ko, Boseong Kim, Jae Hoon Cheong, Chan Young Shin & Jong Hoon Ryu. (2014) Oleanolic acid attenuates MK-801-induced schizophrenia-like behaviors in mice. Neuropharmacology 86, pages 49-56.
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