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Research Article

Allicin enhances chemotherapeutic response and ameliorates tamoxifen-induced liver injury in experimental animals

Pages 1009-1014 | Received 29 Jan 2013, Accepted 11 Dec 2013, Published online: 19 Mar 2014

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Gellan Alaa Mohamed Kamel & Hemat A. Elariny. (2023) Pioglitazone attenuates tamoxifen-induced liver damage in rats via modulating Keap1/Nrf2/HO-1 and SIRT1/Notch1 signaling pathways: In-vivo investigations, and molecular docking analysis. Molecular Biology Reports 50:12, pages 10219-10233.
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Vivek D. Savairam, Neha A. Patil, Shrikant R. Borate, Mahesh M. Ghaisas & Rajkumar V. Shete. (2023) Allicin: A review of its important pharmacological activities. Pharmacological Research - Modern Chinese Medicine 8, pages 100283.
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EsmaNur Bulbul & EmelSerdaroglu Kasikci. (2023) The Toxic effect ways of allicin on different cell Lines. The Journal of Neurobehavioral Sciences 10:2, pages 49.
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Zhanfang Guo & Yanjiao Zhang. (2022) RETRACTED: Allicin promotes autophagy and ferroptosis in esophageal squamous cell carcinoma by activating AMPK/mTOR signaling. Heliyon 8:10.
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Dalia H. El-Kashef & Ahmed R. El-Sheakh. (2019) Hepatoprotective effect of celecoxib against tamoxifen-induced liver injury via inhibiting ASK-1/JNK pathway in female rats. Life Sciences 231, pages 116573.
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Ao Shang, Shi-Yu Cao, Xiao-Yu Xu, Ren-You Gan, Guo-Yi Tang, Harold Corke, Vuyo Mavumengwana & Hua-Bin Li. (2019) Bioactive Compounds and Biological Functions of Garlic (Allium sativum L.). Foods 8:7, pages 246.
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Nahed Mohamed A Hassanein, Azza Abdel-Fattah Ali & Amira Mohy El-Den El-Khawaga. (2019) Methylseleninic Acid and Grape Seed Extract Alleviate Tamoxifen Induce Hepatotoxicity in Rats. Toxicology and Environmental Health Sciences 10:5, pages 278-287.
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Voin Petrovic, Anala Nepal, Camilla Olaisen, Siri Bachke, Jonathan Hira, Caroline Søgaard, Lisa Røst, Kristine Misund, Trygve Andreassen, Torun Melø, Zdenka Bartsova, Per Bruheim & Marit Otterlei. (2018) Anti-Cancer Potential of Homemade Fresh Garlic Extract Is Related to Increased Endoplasmic Reticulum Stress. Nutrients 10:4, pages 450.
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Yosra SR Elnaggar, Manal A Elsheikh & Ossama Y Abdallah. (2018) Phytochylomicron as a dual nanocarrier for liver cancer targeting of luteolin: in vitro appraisal and pharmacodynamics . Nanomedicine 13:2, pages 209-232.
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Mohamed M. Abdel-Daim, Omnia E. kilany, Hesham A. Khalifa & Amal A. M. Ahmed. (2017) Allicin ameliorates doxorubicin-induced cardiotoxicity in rats via suppression of oxidative stress, inflammation and apoptosis. Cancer Chemotherapy and Pharmacology 80:4, pages 745-753.
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Jie Zheng, Yue Zhou, Ya Li, Dong-Ping Xu, Sha Li & Hua-Bin Li. (2016) Spices for Prevention and Treatment of Cancers. Nutrients 8:8, pages 495.
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Xuejing Zou, Jiyun Liang, Jingyuan Sun, Xiaoyun Hu, Ling Lei, Dehua Wu & Li Liu. (2016) Allicin sensitizes hepatocellular cancer cells to anti-tumor activity of 5-fluorouracil through ROS-mediated mitochondrial pathway. Journal of Pharmacological Sciences 131:4, pages 233-240.
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Rodrigo Arreola, Saray Quintero-Fabián, Rocío Ivette López-Roa, Enrique Octavio Flores-Gutiérrez, Juan Pablo Reyes-Grajeda, Lucrecia Carrera-Quintanar & Daniel Ortuño-Sahagún. (2015) Immunomodulation and Anti-Inflammatory Effects of Garlic Compounds. Journal of Immunology Research 2015, pages 1-13.
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T. K. LimT. K. Lim. 2015. Edible Medicinal and Non Medicinal Plants. Edible Medicinal and Non Medicinal Plants 210 360 .
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Zhanfang Guo & Yanjiao Zhang. (2022) Allicin Promotes Autophagy and Ferroptosis in Esophageal Squamous Cell Carcinoma by Activating AMPK/mTOR Signaling. SSRN Electronic Journal.
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