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Original Article

An ethanol extract of Origanum vulgare attenuates cyclophosphamide-induced pulmonary injury and oxidative lung damage in mice

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Pages 1229-1236 | Received 21 Oct 2013, Accepted 27 Dec 2013, Published online: 19 Mar 2014

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Mehmet Berköz, Serap Yalın, Ferbal Özkan-Yılmaz, Arzu Özlüer-Hunt, Mirosław Krośniak, Renata Francik, Oruç Yunusoğlu, Abdullah Adıyaman, Hava Gezici, Ayhan Yiğit, Seda Ünal, Davut Volkan & Metin Yıldırım. (2021) Protective effect of myricetin, apigenin, and hesperidin pretreatments on cyclophosphamide-induced immunosuppression. Immunopharmacology and Immunotoxicology 43:3, pages 353-369.
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Emran Habibi, Mohammad Shokrzadeh, Aroona Chabra, Farshad Naghshvar, Razieh Keshavarz-Maleki & Amirhossein Ahmadi. (2015) Protective effects of Origanum vulgare ethanol extract against cyclophosphamide-induced liver toxicity in mice. Pharmaceutical Biology 53:1, pages 10-15.
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Articles from other publishers (27)

Xinyue Li, Meng Zhao, Zikang Ding, Xiaomei Wang & Zhongshan Zhang. (2023) C-phycocyanin ameliorates cyclophosphamide-induced liver injury and metabolic disorder through the modulation of the gut microbiota in mice. Algal Research 71, pages 103093.
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Liandra Ferreira Minhos, Ana Cláudia da Silva de Lima Gehlen, Felipe Francisco Bittencourt Júnior, Ariany Carvalho dos Santos, Roosevelt Isaias Carvalho Souza & Márcio Eduardo de Barros. (2023) Evaluation of the Efficacy of Lactobacillus acidophilus in the Treatment of Cyclophosphamide-induced Hemorrhagic Cystitis in Wistar Rats. Current Pharmaceutical Biotechnology 24:3, pages 438-449.
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Nashwah G. M. Attallah, Amal Kabbash, Walaa A. Negm, Engy Elekhnawy, Reem Binsuwaidan, Omnia Momtaz Al-Fakhrany, Moataz A. Shaldam, Ehssan Moglad, Marwa Tarek, Nehal Samir & Heba M. Fawzy. (2023) Protective Potential of Saussurea costus (Falc.) Lipsch. Roots against Cyclophosphamide-Induced Pulmonary Injury in Rats and Its In Vitro Antiviral Effect. Pharmaceuticals 16:2, pages 318.
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Emad H. M. Hassanein, Esam O. Kamel, Wail M. Gad-Elrab, Mohammed A. Ahmed, Zuhair M. Mohammedsaleh & Fares E. M. Ali. (2023) Lansoprazole attenuates cyclophosphamide-induced cardiopulmonary injury by modulating redox-sensitive pathways and inflammation. Molecular and Cellular Biochemistry.
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I. Liaqat, A. Mahreen, M. Arshad & N. Arshad. (2023) Antimicrobial and toxicological evaluation of Origanum vulgare: an in vivo study. Brazilian Journal of Biology 83.
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Cristina C Uclaray, Mark Louis P Vidallon, Ronaniel A Almeda, Christian Joseph R Cumagun, Charisse T Reyes & Evelyn B Rodriguez. (2022) Encapsulation of wild oregano, Plectranthus amboinicus ( Lour. ) Spreng , phenolic extract in baker's yeast for the postharvest control of anthracnose in papaya . Journal of the Science of Food and Agriculture 102:11, pages 4657-4667.
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Maryam Armandeh, Behnaz Bameri, Mahedeh Samadi, Shima Heidari, Roham Foroumadi & Mohammad Abdollahi. (2022) A Systematic Review of Nonclinical Studies on the Effect of Curcumin in Chemotherapy- induced Cardiotoxicity. Current Pharmaceutical Design 28:22, pages 1843-1853.
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Saeideh Saadat, Sima Beigoli, Mohammad Reza Khazdair, Fatemeh Amin & Mohammad Hossein Boskabady. (2022) Experimental and Clinical Studies on the Effects of Natural Products on Noxious Agents-Induced Lung Disorders, a Review. Frontiers in Nutrition 9.
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Amira Ebrahim Alsemeh & Doaa M. Abdullah. (2022) Protective effect of alogliptin against cyclophosphamide-induced lung toxicity in rats: Impact on PI3K/Akt/FoxO1 pathway and downstream inflammatory cascades. Cell and Tissue Research 388:2, pages 417-438.
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Mariame Najem, Jamal Ibijbijen & Laila Nassiri. (2021) Ethnobotanical treatment of respiratory diseases in the central Middle Atlas (Morocco): Qualitative and quantitative approach. European Journal of Integrative Medicine 46, pages 101358.
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Khaled G. Abdel-Wahhab, Fathia A. Mannaa, Mahmoud Ashry, Doaa M. Khaled, Laila K. Hassan & Heba F. Gomaa. (2021) Chenopodium quinoa ethanolic extract ameliorates cyclophosphamide®-induced hepatotoxicity in male rats. Comparative Clinical Pathology 30:2, pages 267-276.
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Amirhossein Ahmadi. (2021) The Beneficial Roles of Herbal Medicine and Natural Product in CNS Disorders and Neurodegeneration. Current Pharmaceutical Design 27:3, pages 331-331.
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Mahedeh Samadi, Hamed Haghi-Aminjan, Mohammadreza Sattari, Mohammad Reza Hooshangi Shayesteh, Behnaz Bameri, Maryam Armandeh, Mastoureh Naddafi, Mohammad Ali Eghbal & Mohammad Abdollahi. (2021) The role of taurine on chemotherapy-induced cardiotoxicity: A systematic review of non-clinical study. Life Sciences 265, pages 118813.
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Rania M Salama, Abdelkader M Mohamed, Nada S Hamed, Raneem M Ata, Amira S NourelDeen & Mohamed A Hassan. (2020) Alogliptin: a novel approach against cyclophosphamide-induced hepatic injury via modulating SIRT1/FoxO1 pathway. Toxicology Research 9:4, pages 561-568.
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María Pilar de Torre, Jose Luis Vizmanos, Rita Yolanda Cavero & María Isabel Calvo. (2020) Improvement of antioxidant activity of oregano (Origanum vulgare L.) with an oral pharmaceutical form. Biomedicine & Pharmacotherapy 129, pages 110424.
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ghader rahimzadeh, Mohamad Ali Azarbaijani & Hasan Matin Homaei. (2020) Comparing the effect of aerobic training, origanum vulgare extract supplementation and their combination on oxidative stress and inflammatory biomarkers on male rats. Medical Journal of Tabriz University of Medical Sciences and Health Services 42:3, pages 254-262.
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Mahmoud Alagawany, Mohamed E. Abd El-Hack, Mayada R. Farag, Hazem M. Shaheen, Mervat A. Abdel-Latif, Ahmed E. Noreldin & Asmaa F. Khafaga. (2020) The Applications of Origanum Vulgare and Its Derivatives in Human, Ruminant and Fish Nutrition – A Review . Annals of Animal Science 20:2, pages 389-407.
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Nastaran Azarbarz, Zeinab Shafiei Seifabadi, Maasoumeh Zare Moaiedi & Esrafil Mansouri. (2020) Assessment of the effect of sodium hydrogen sulfide (hydrogen sulfide donor) on cisplatin-induced testicular toxicity in rats. Environmental Science and Pollution Research 27:8, pages 8119-8128.
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Heibatullah Kalantari, Nooshin Asadmasjedi, Mohammad reza Abyaz, Masoud Mahdavinia & Narges Mohammadtaghvaei. (2019) Protective effect of inulin on methotrexate- induced liver toxicity in mice. Biomedicine & Pharmacotherapy 110, pages 943-950.
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Hassan Askari, Mohammad Foad Abazari, Pegah Ghoraeian, Sepehr Torabinejad, Maryam Nouri Aleagha, Reza Mirfallah Nassiri, Farshid Tahmasebi, Nairi Abedi, Sulail Fatima Rajani, Ali Salarian, Maryam Belaran, Mohammed Elshiekh & Nima Sanadgol. (2018) Ameliorative effects of hydrogen sulfide (NaHS) on chronic kidney disease-induced brain dysfunction in rats: implication on role of nitric oxide (NO) signaling. Metabolic Brain Disease 33:6, pages 1945-1954.
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Chandrashekhar Singh, Chandra Prakash, Kavindra Nath Tiwari, Sunil Kumar Mishra & Vijay Kumar. (2018) Premna integrifolia ameliorates cyclophosphamide-induced hepatotoxicity by modulation of oxidative stress and apoptosis. Biomedicine & Pharmacotherapy 107, pages 634-643.
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Hassan Askari, Sulail Fatima Rajani, Mansour Poorebrahim, Hamed Haghi-Aminjan, Ehsan Raeis-Abdollahi & Mohammad Abdollahi. (2018) A glance at the therapeutic potential of irisin against diseases involving inflammation, oxidative stress, and apoptosis: An introductory review. Pharmacological Research 129, pages 44-55.
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Hamed Haghi-Aminjan, Mohammad Hossein Asghari, Bagher Farhood, Mahban Rahimifard, Nasser Hashemi Goradel & Mohammad Abdollahi. (2018) The role of melatonin on chemotherapy-induced reproductive toxicity. Journal of Pharmacy and Pharmacology 70:3, pages 291-306.
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Emin Şengül, Volkan Gelen, Semin Gedikli, Seçkin Özkanlar, Cihan Gür, Fikret Çelebi & Ali Çınar. (2017) The protective effect of quercetin on cyclophosphamide-Induced lung toxicity in rats. Biomedicine & Pharmacotherapy 92, pages 303-307.
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Maria C. Capellini, Fernanda H. Carvalho, Cristina C. Koshima, Keila K. Aracava, Cintia B. Gonçalves & Christianne E.C. Rodrigues. (2015) Phase equilibrium data for systems composed of oregano essential oil compounds and hydroalcoholic solvents at T=298.2K. The Journal of Chemical Thermodynamics 88, pages 61-71.
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Mohammad Shokrzadeh, Amirhossein Ahmadi, Farshad Naghshvar, Aroona Chabra & Mehdi Jafarinejhad. (2014) Prophylactic Efficacy of Melatonin on Cyclophosphamide-Induced Liver Toxicity in Mice. BioMed Research International 2014, pages 1-6.
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