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Original Article

The effect of lipoic acid on acrylamide-induced neuropathy in rats with reference to biochemical, hematological, and behavioral alterations

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Pages 1207-1213 | Received 27 Mar 2014, Accepted 23 Sep 2014, Published online: 08 Apr 2015

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Soha M. Hamdy, Zakaria El-Khayat, Abdel Razik Farrag, Ola N. Sayed, Mervat M. El-Sayed & Diaa Massoud. (2022) Hepatoprotective effect of Raspberry ketone and white tea against acrylamide-induced toxicity in rats. Drug and Chemical Toxicology 45:2, pages 722-730.
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Tianyao Yang, Zhaofa Xu, Wei Liu, Bin Xu & Yu Deng. (2016) Protective effects of Alpha-lipoic acid on MeHg-induced oxidative damage and intracellular Ca2+ dyshomeostasis in primary cultured neurons. Free Radical Research 50:5, pages 542-556.
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Articles from other publishers (18)

Fangfang Yan, Li Wang, Li Zhao, Chengming Wang, Qun Lu & Rui Liu. (2023) Acrylamide in food: Occurrence, metabolism, molecular toxicity mechanism and detoxification by phytochemicals. Food and Chemical Toxicology 175, pages 113696.
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Wafa Trabelsi, Chaima Fouzai, Khaoula Telahigue, Imene Chetoui, Salwa Nechi, Emna Chelbi, Sonia Zrelli & Nejla Soudani. (2022) The potential adverse effects of acrylamide on the oxidative stress response, fatty acids profile, and histopathological aspect of the Mediterranean Holothuria forskali respiratory tree . Environmental Toxicology 38:1, pages 159-171.
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Kojo Eghan, Sangwoo Lee & Woo-Keun Kim. (2022) Cardiotoxicity and neurobehavioral effects induced by acrylamide in Daphnia magna. Ecotoxicology and Environmental Safety 242, pages 113923.
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Muhammed Atamanalp, Hasan Türkez, Aslı Çilingir Yeltekin, Fatma Betül Özgeriş, Arzu Ucar, Özge Çağlar, Veysel Parlak, Sena Oner & Gonca Alak. (2022) Borax relieved the acrylamide-induced hematotoxic, hepatotoxic, immunotoxic and genotoxic damages in rainbow trout by regulating apoptosis and Nrf2 signaling pathway. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 259, pages 109396.
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Prathyusha Cota, Sayantani Saha, Shailvi Tewari, Abhirami Sasikumar, M. Yashwant Saran, Swetha Senthilkumar & Sahabudeen Sheik Mohideen. 2022. Hazardous Waste Management. Hazardous Waste Management.
Mengyao Zhao, Linlin Deng, Xiaoxuan Lu, Liqiang Fan, Yang Zhu & Liming Zhao. (2022) The involvement of oxidative stress, neuronal lesions, neurotransmission impairment, and neuroinflammation in acrylamide-induced neurotoxicity in C57/BL6 mice. Environmental Science and Pollution Research 29:27, pages 41151-41167.
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Hany Elsawy, Abdullah M. Alzahrani, Manal Alfwuaires, Azza Sedky, Eman E. El- Trass, Omar Mahmoud, Ashraf M. Abdel-Moneim & Mahmoud Khalil. (2021) Analysis of silymarin-modulating effects against acrylamide-induced cerebellar damage in male rats: Biochemical and pathological markers. Journal of Chemical Neuroanatomy 115, pages 101964.
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Sameh M. Farouk, Fatma A. Gad, Rafa Almeer, Mohamed M. Abdel-Daim & Mahmoud A. Emam. (2021) Exploring the possible neuroprotective and antioxidant potency of lycopene against acrylamide-induced neurotoxicity in rats’ brain. Biomedicine & Pharmacotherapy 138, pages 111458.
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Marwa Abdeltawab MohammedDoaa Mostafa GharibHoda Ramadan ReyadAlaa Aboud MohamedFadwa A. ElrobyHoda Sayed Mahmoud. (2021) Antioxidant and anti-inflammatory properties of alpha-lipoic acid protect against valproic acid–induced liver injury. Canadian Journal of Physiology and Pharmacology 99:5, pages 499-505.
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Ola M. Farag, Reham M. Abd-Elsalam, Hanan A. Ogaly, Sara E. Ali, Shymaa A. El Badawy, Muhammed A. Alsherbiny, Chun Guang Li & Kawkab A. Ahmed. (2021) Metabolomic Profiling and Neuroprotective Effects of Purslane Seeds Extract Against Acrylamide Toxicity in Rat’s Brain. Neurochemical Research 46:4, pages 819-842.
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Jong-Su Park, Palas Samanta, Sangwoo Lee, Jieon Lee, Jae-Woo Cho, Hang-Suk Chun, Seokjoo Yoon & Woo-Keun Kim. (2021) Developmental and Neurotoxicity of Acrylamide to Zebrafish. International Journal of Molecular Sciences 22:7, pages 3518.
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Mohammad Hossein Asghari, Milad Moloudizargari & Mohammad Abdollahi. 2021. Mitochondrial Physiology and Vegetal Molecules. Mitochondrial Physiology and Vegetal Molecules 689 707 .
Sadhana Shrivastava, Satendra K. Nirala, Mohammad S. Reshi, Sangeeta Shukla, Anjali Sharma & Chhavi Uthra. (2019) Protective Efficacy of Vitamin F against Acrylamide Induced Toxicity: Studies on Oxidative Stress Biomarkers. The Open Biomarkers Journal 9:1, pages 62-69.
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Mohamed A. Lebda, Kadry M. Sadek, Hossam G. Tohamy, Tarek K. Abouzed, Mostafa Shukry, Masakazu Umezawa & Yasser S. El-Sayed. (2018) Potential role of α-lipoic acid and Ginkgo biloba against silver nanoparticles-induced neuronal apoptosis and blood-brain barrier impairments in rats. Life Sciences 212, pages 251-260.
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Jasim Khan, Shikha Salhotra, Shahzad Ahmad, Shikha Sharma, Sayed Aliul Hasan Abdi, Basu Dev Banerjee, Suhel Parvez, Sarika Gupta & Sheikh Raisuddin. (2018) The protective effect of α-lipoic acid against bisphenol A-induced neurobehavioral toxicity. Neurochemistry International 118, pages 166-175.
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Mehmet Erman Erdemli, M. Arif Aladag, Eyup Altinoz, Sezin Demirtas, Yusuf Turkoz, Birgül Yigitcan & Harika Gozukara Bag. (2018) Acrylamide applied during pregnancy causes the neurotoxic effect by lowering BDNF levels in the fetal brain. Neurotoxicology and Teratology 67, pages 37-43.
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Ge Song, Zhigang Liu, Qian Liu & Xuebo Liu. (2017) Lipoic acid prevents acrylamide-induced neurotoxicity in CD-1 mice and BV2 microglial cells via maintaining redox homeostasis. Journal of Functional Foods 35, pages 363-375.
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Ge Song, Zhigang Liu, Luanfeng Wang, Renjie Shi, Chuanqi Chu, Man Xiang, Qi Tian & Xuebo Liu. (2017) Protective effects of lipoic acid against acrylamide-induced neurotoxicity: involvement of mitochondrial energy metabolism and autophagy. Food & Function 8:12, pages 4657-4667.
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