5,494
Views
69
CrossRef citations to date
0
Altmetric
Review Article

Vitamin D in cancer chemoprevention

, , , , , , & show all
Pages 1399-1434 | Received 21 Aug 2014, Accepted 12 Nov 2014, Published online: 09 Apr 2015

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Zhangyou Guo, Ming Huang, Dandan Fan, Yuan Hong, Min Zhao, Rong Ding, Yao Cheng & Shigang Duan. (2023) Association between vitamin D supplementation and cancer incidence and mortality: A trial sequential meta-analysis of randomized controlled trials. Critical Reviews in Food Science and Nutrition 63:26, pages 8428-8442.
Read now
Weijie Wang, Wentao Hu, Shihang Xue, Qi Chen, Yongsheng Jiang, Haina Zhang & Wei Zuo. (2021) Vitamin D and Lung Cancer; Association, Prevention, and Treatment. Nutrition and Cancer 73:11-12, pages 2188-2200.
Read now
Mohamed Kacem Ben Fradj, Mokhtar Bibi, Mohamed Bassem Hammami, Amani Kallel, Yassine Nouira & Moncef Feki. (2021) Low Plasma 25-Hydoxyvitamin D at Diagnosis Predicts Poor Outcomes in Patients with Bladder Cancer: A Prospective Cohort Study. Nutrition and Cancer 73:1, pages 55-61.
Read now

Articles from other publishers (66)

Marjolein van Driel, Alberto Muñoz & Johannes P.T.M. van Leeuwen. 2024. Feldman and Pike's Vitamin D. Feldman and Pike's Vitamin D 679 718 .
Konstantinos Seretis, Nikolaos Bounas & Chrissa Sioka. (2023) The Association of Vitamin D with Non-Melanoma Skin Cancer Risk: An Umbrella Review of Systematic Reviews and Meta-Analyses. Medicina 59:12, pages 2130.
Crossref
Komal S. Wakle, Santosh N. Mokale & Nikhil S. Sakle. (2023) Emerging perspectives: unraveling the anticancer potential of vitamin D3. Naunyn-Schmiedeberg's Archives of Pharmacology.
Crossref
Yuxuan Dai, Yu Chen, Yifu Pu & Rui Jiang. (2023) Circulating vitamin D concentration and risk of 14 cancers: a bidirectional Mendelian randomization study. Journal of Cancer Research and Clinical Oncology 149:17, pages 15457-15467.
Crossref
Sha Sha, Li-Ju Chen, Hermann Brenner & Ben Schöttker. (2023) Associations of 25-hydroxyvitamin D status and vitamin D supplementation use with mortality due to 18 frequent cancer types in the UK Biobank cohort. European Journal of Cancer 191, pages 113241.
Crossref
Jiao-Jiao Ren, Zhi-Hao Li, Wen-Fang Zhong, Pei-Liang Chen, Qing-Mei Huang, Xiao-Meng Wang, Ping-Ming Gao & Chen Mao. (2023) Serum 25-hydroxyvitamin D concentrations and colorectal cancer incidence in adults with type 2 diabetes. British Journal of Cancer 129:3, pages 486-491.
Crossref
Manpreet Kaur, Surekha Bhatia, Urmila Gupta, Eric Decker, Yamini Tak, Manoj Bali, Vijai Kumar Gupta, Rouf Ahmad Dar & Saroj Bala. (2023) Microalgal bioactive metabolites as promising implements in nutraceuticals and pharmaceuticals: inspiring therapy for health benefits. Phytochemistry Reviews 22:4, pages 903-933.
Crossref
Adem AKÇAKAYA. (2023) Does Vitamin D Prevent Cancer?. Bezmialem Science 11:2, pages 138-140.
Crossref
Zsuzsanna Nemeth, Attila Patonai, Laura Simon-Szabó & István Takács. (2023) Interplay of Vitamin D and SIRT1 in Tissue-Specific Metabolism—Potential Roles in Prevention and Treatment of Non-Communicable Diseases Including Cancer. International Journal of Molecular Sciences 24:7, pages 6154.
Crossref
Lu Zhang, Éva Pozsgai, Yongan Song, John Macharia, Huda Alfatafta, Jia Zheng, Zhaoyi Li, Hongbo Liu & István Kiss. (2023) The relationship between single nucleotide polymorphisms and skin cancer susceptibility: A systematic review and network meta-analysis. Frontiers in Oncology 13.
Crossref
Lyubov S. Klyushova, Maria L. Perepechaeva & Alevtina Y. Grishanova. (2022) The Role of CYP3A in Health and Disease. Biomedicines 10:11, pages 2686.
Crossref
Friedrich Jung, Steffen Braune, Conrad H. G. Jung, Anne Krüger-Genge, Peter Waldeck, Ingolf Petrick & Jan-Heiner Küpper. (2022) Lipophilic and Hydrophilic Compounds from Arthrospira platensis and Its Effects on Tissue and Blood Cells—An Overview. Life 12:10, pages 1497.
Crossref
Rana Abdelwahab, Ruimin Huang, Shanthi Potla, Sushen Bhalla, Yousif AlQabandi, Savitri Aninditha Nandula, Chinmayi Sree Boddepalli, Sai Dheeraj Gutlapalli, Vamsi Krishna Lavu & Lubna Mohammed. (2022) The Relationship between Vitamin D and Basal Cell Carcinoma: A Systematic Review. Cureus.
Crossref
Siva Swapna Kasarla, Vannuruswamy Garikapati, Yashwant Kumar & Sujatha Dodoala. (2022) Interplay of Vitamin D and CYP3A4 Polymorphisms in Endocrine Disorders and Cancer. Endocrinology and Metabolism 37:3, pages 392-407.
Crossref
Ahmed Abdelgawad, Abdelwahab Hashem, Ahmed Mosbah & Laila A. Eissa. (2022) A prospective trial investigating the role of Serum 25-Hydroxyvitamin D in diagnosis and prognosis of bladder cancer. PLOS ONE 17:6, pages e0266371.
Crossref
Vijay Ganji, Layan Sukik, Bushra Hoque, Linda Boutefnouchet & Zumin Shi. (2022) Association of Serum 25-Hydroxyvitamin D Concentration with Breast Cancer Risk in Postmenopausal Women in the US. Journal of Personalized Medicine 12:6, pages 944.
Crossref
Danila Di Majo, Francesco Cacciabaudo, Giulia Accardi, Giuditta Gambino, Giuseppe Giglia, Giuseppe Ferraro, Giuseppina Candore & Pierangelo Sardo. (2022) Ketogenic and Modified Mediterranean Diet as a Tool to Counteract Neuroinflammation in Multiple Sclerosis: Nutritional Suggestions. Nutrients 14:12, pages 2384.
Crossref
Meifang Zheng & Runping Gao. (2022) Vitamin D: A Potential Star for Treating Chronic Pancreatitis. Frontiers in Pharmacology 13.
Crossref
Michell Fullmer, Annelise Su, Steven Bachrach, Jobayer Hossain & Heidi H. Kecskemethy. (2022) Newly Diagnosed Children with Cancer Have Lower 25-Vitamin D Levels than Their Cancer-Free Peers: A Comparison across Age, Race, and Sex. Cancers 14:10, pages 2378.
Crossref
Negar Khazan, Kyu Kwang Kim, Jeanne N. Hansen, Niloy A. Singh, Taylor Moore, Cameron W. A. Snyder, Ravina Pandita, Myla Strawderman, Michiko Fujihara, Yuta Takamura, Ye Jian, Nicholas Battaglia, Naohiro Yano, Yuki Teramoto, Leggy A. Arnold, Russell Hopson, Keshav Kishor, Sneha Nayak, Debasmita Ojha, Ashoke Sharon, John M. Ashton, Jian Wang, Michael T. Milano, Hiroshi Miyamoto, David C. Linehan, Scott A. Gerber, Nada Kawar, Ajay P. Singh, Erdem D. Tabdanov, Nikolay V. Dokholyan, Hiroki Kakuta, Peter W. Jurutka, Nina F. Schor, Rachael B. Rowswell-Turner, Rakesh K. Singh & Richard G. Moore. (2022) Identification of a Vitamin-D Receptor Antagonist, MeTC7, which Inhibits the Growth of Xenograft and Transgenic Tumors In Vivo . Journal of Medicinal Chemistry 65:8, pages 6039-6055.
Crossref
Silvia Migliaccio, Andrea Di Nisio, Silvia Magno, Fiammetta Romano, Luigi Barrea, Anna Maria Colao, Giovanna Muscogiuri & Silvia Savastano. (2022) Vitamin D deficiency: a potential risk factor for cancer in obesity?. International Journal of Obesity 46:4, pages 707-717.
Crossref
Ioanna-Maria Gkotinakou, Ilias Mylonis & Andreas Tsakalof. (2022) Vitamin D and Hypoxia: Points of Interplay in Cancer. Cancers 14:7, pages 1791.
Crossref
Stephanie J Weinstein, Alison M Mondul, Tracy M Layne, Kai Yu, Jiaqi Huang, Rachael Z Stolzenberg-Solomon, Regina G Ziegler, Mark P Purdue, Wen-Yi Huang, Christian C Abnet, Neal D Freedman & Demetrius Albanes. (2022) Prediagnostic Serum Vitamin D, Vitamin D Binding Protein Isoforms, and Cancer Survival. JNCI Cancer Spectrum 6:2.
Crossref
Rahul Kumar Goswami, Sanjeet Mehariya, Obulisamy Parthiba Karthikeyan, Vijai Kumar Gupta & Pradeep Verma. (2022) Multifaceted application of microalgal biomass integrated with carbon dioxide reduction and wastewater remediation: A flexible concept for sustainable environment. Journal of Cleaner Production 339, pages 130654.
Crossref
Kemal Hansu & Ismail Gurkan Cikim. (2022) Vitamin and mineral levels during pregnancy. Revista da Associação Médica Brasileira 68:12, pages 1705-1708.
Crossref
Amal F Gharib, Ahmad El Askary, Mazen Almehmadi, Hayaa M Alhuthali, Wael H Elsawy, Hatem H Allam, Lamiaa K Elsayyad, Manal Ali Ayoub & Alaa Shafie. (2022) Association of vitamin D deficiency and inflammatory cytokines with the clinicopathological features of breast cancer in female Saudi patients. European Journal of Inflammation 20, pages 1721727X2211065.
Crossref
Emanuele Salvatore Scarpa, Marco Giammanco & Mauro Magnani. (2021) Gastrointestinal Tumors: Phytochemical and Drug Combinations Targeting the Hallmarks of Cancer. Applied Sciences 11:21, pages 10077.
Crossref
Maria Scuto, Angela Trovato Salinaro, Isabella Caligiuri, Maria Laura Ontario, Valentina Greco, Nello Sciuto, Roberto Crea, Edward J. Calabrese, Flavio Rizzolio, Vincenzo Canzonieri & Vittorio Calabrese. (2021) Redox modulation of vitagenes via plant polyphenols and vitamin D: Novel insights for chemoprevention and therapeutic interventions based on organoid technology. Mechanisms of Ageing and Development 199, pages 111551.
Crossref
Carlos Jiménez-Cortegana, Pilar M. Sánchez-Martínez, Natalia Palazón-Carrión, Esteban Nogales-Fernández, Fernando Henao-Carrasco, Alejandro Martín García-Sancho, Antonio Rueda, Mariano Provencio, Luis de la Cruz-Merino & Víctor Sánchez-Margalet. (2021) Lower Survival and Increased Circulating Suppressor Cells in Patients with Relapsed/Refractory Diffuse Large B-Cell Lymphoma with Deficit of Vitamin D Levels Using R-GDP Plus Lenalidomide (R2-GDP): Results from the R2-GDP-GOTEL Trial. Cancers 13:18, pages 4622.
Crossref
Anna Gabryanczyk, Sylwia Klimczak, Izabela Szymczak-Pajor & Agnieszka Śliwińska. (2021) Is Vitamin D Deficiency Related to Increased Cancer Risk in Patients with Type 2 Diabetes Mellitus?. International Journal of Molecular Sciences 22:12, pages 6444.
Crossref
Luigi BARREA, Evelyn FRIAS-TORAL, Gabriella PUGLIESE, Eloisa GARCIA-VELASQUEZ, Maria DE LOS ANGELES CARIGNANO, Silvia SAVASTANO, Annamaria COLAO & Giovanna MUSCOGIURI. (2021) Vitamin D in obesity and obesity-related diseases: an overview. Minerva Endocrinology 46:2.
Crossref
Boda Ravi Kiran & S. Venkata Mohan. (2021) Microalgal Cell Biofactory—Therapeutic, Nutraceutical and Functional Food Applications. Plants 10:5, pages 836.
Crossref
Carmen Griñan-Lison, Jose L. Blaya-Cánovas, Araceli López-Tejada, Marta Ávalos-Moreno, Alba Navarro-Ocón, Francisca E. Cara, Adrián González-González, Jose A. Lorente, Juan A. Marchal & Sergio Granados-Principal. (2021) Antioxidants for the Treatment of Breast Cancer: Are We There Yet?. Antioxidants 10:2, pages 205.
Crossref
Marianna Nikiforou-Lialiampidou, Marius Moga, Matthias Kalder, George-Chrysostomos Pratilas & Konstantinos Dinas. 2021. Handbook of Research on Oncological and Endoscopical Dilemmas in Modern Gynecological Clinical Practice. Handbook of Research on Oncological and Endoscopical Dilemmas in Modern Gynecological Clinical Practice 338 354 .
María Morales-Suárez-Varela, Amparo Ruiz Simon, Salvador Blanch Tormo, Ismael Pastor Climente, Maximino Redondo Bautista, Isabel Peraita-Costa, Agustin Llopis-Morales & Agustin Llopis-Gonzalez. (2020) Effect of Breast Cancer Treatment on Dietary Vitamin Intake Levels. International Journal of Environmental Research and Public Health 18:1, pages 19.
Crossref
Sachin Bhoora & Rivak Punchoo. (2020) Policing Cancer: Vitamin D Arrests the Cell Cycle. International Journal of Molecular Sciences 21:23, pages 9296.
Crossref
Angelo Del Mondo, Arianna Smerilli, Elisabet Sané, Clementina Sansone & Christophe Brunet. (2020) Challenging microalgal vitamins for human health. Microbial Cell Factories 19:1.
Crossref
Afsane Bahrami & Amirhossein Sahebkar. (2020) Vitamin D as a Potential Therapeutic Option in Cancer Treatment: Is There a Role for Chemoprevention?. Anti-Cancer Agents in Medicinal Chemistry 20:18, pages 2138-2149.
Crossref
I.B. Adelani, E.O. Ogadi, C. Onuzulu, O.A. Rotimi, E.N. Maduagwu & S.O. Rotimi. (2020) Dietary vitamin D ameliorates hepatic oxidative stress and inflammatory effects of diethylnitrosamine in rats. Heliyon 6:9, pages e04842.
Crossref
Mirela Ibrahimovic, Elizabeth Franzmann, Alison M. Mondul, Katherine M. Weh, Connor Howard, Jennifer J. Hu, W. Jarrard Goodwin & Laura A. Kresty. (2020) Disparities in Head and Neck Cancer: A Case for Chemoprevention with Vitamin D. Nutrients 12:9, pages 2638.
Crossref
Ahmed El-Sharkawy & Ahmed Malki. (2020) Vitamin D Signaling in Inflammation and Cancer: Molecular Mechanisms and Therapeutic Implications. Molecules 25:14, pages 3219.
Crossref
Magdy Yossef Elsaeed, El-sayed Hamdey El-sayed Gawesh, Amal Mahmoud Hammad & Walaa Mohamed Omar Ashry. (2020) Vitamin D Ameliorates Oxidative and Inflammatory Effects of Hepatorenal Injury of Acute Paracetamol Toxicity: An experimental study. The Scientific Journal of Medical Scholar 2020:4, pages 96-102.
Crossref
Neda Vishlaghi & Thomas S. Lisse. (2020) Exploring vitamin D signalling within skin cancer. Clinical Endocrinology 92:4, pages 273-281.
Crossref
Uzma Shamsi & Shaheryar Usman. (2020) Causal association of Vitamin D deficiency with cancer: More research needed. Cancer Research, Statistics, and Treatment 3:2, pages 369.
Crossref
Ebtesam Abdullah Al-Suhaimi, Khulood Mohammed Al-Khater, Meneerah Abdurhman Aljafary, Vijaya Ravinayagam, Adeeb Shehzad, Hanan A. Al-Dossary, Reem A. Assuhaimi, Mohamad Tarhini & Abdelhamid Elaissari. 2020. Cancer-Leading Proteases. Cancer-Leading Proteases 417 448 .
Pardeep Kaur. 2020. Microbial Biotechnology: Basic Research and Applications. Microbial Biotechnology: Basic Research and Applications 91 125 .
Cindy Flamann, Katrin Peter, Marina Kreutz & Heiko Bruns. (2019) Regulation of the Immune Balance During Allogeneic Hematopoietic Stem Cell Transplantation by Vitamin D. Frontiers in Immunology 10.
Crossref
Jianmin Han, Xiaofei Guo, Xiao Yu, Shuang Liu, Xinyue Cui, Bo Zhang & Hui Liang. (2019) 25-Hydroxyvitamin D and Total Cancer Incidence and Mortality: A Meta-Analysis of Prospective Cohort Studies. Nutrients 11:10, pages 2295.
Crossref
Phil Trabulsy. 2019. Cancer. Cancer 499 530 .
Agata Jagielska, Anna Ruszczyńska, Barbara Wagner, Ewa Bulska, Dorota Skrajnowska & Barbara Bobrowska-Korczak. (2019) ICP-MS analysis of diet supplementation influence on the elemental content of rat prostate gland. Monatshefte für Chemie - Chemical Monthly 150:9, pages 1681-1690.
Crossref
Himangshu Sarma, Taslima Jahan & Hemanta K. Sharma. (2019) Progress in Drug and Formulation Development for the Chemoprevention of Oral Squamous Cell Carcinoma: A Review. Recent Patents on Drug Delivery & Formulation 13:1, pages 16-36.
Crossref
Hannah B. Mandle, Ferdous A. Jahan, Roberd M. Bostick, John A. Baron, Elizabeth L. Barry, Rami Yacoub, Julia Merrill, Robin E. Rutherford, March E. Seabrook & Veronika Fedirko. (2019) Effects of supplemental calcium and vitamin D on tight‐junction proteins and mucin‐12 expression in the normal rectal mucosa of colorectal adenoma patients. Molecular Carcinogenesis 58:7, pages 1279-1290.
Crossref
Magdalena Milczarek, Joanna Rossowska, Dagmara Klopotowska, Martyna Stachowicz, Andrzej Kutner & Joanna Wietrzyk. (2019) Tacalcitol increases the sensitivity of colorectal cancer cells to 5-fluorouracil by downregulating the thymidylate synthase. The Journal of Steroid Biochemistry and Molecular Biology 190, pages 139-151.
Crossref
Christian Galasso, Antonio Gentile, Ida Orefice, Adrianna Ianora, Antonino Bruno, Douglas M. Noonan, Clementina Sansone, Adriana Albini & Christophe Brunet. (2019) Microalgal Derivatives as Potential Nutraceutical and Food Supplements for Human Health: A Focus on Cancer Prevention and Interception. Nutrients 11:6, pages 1226.
Crossref
Simone Mocellin, Annabel Goodwin & Sandro Pasquali. (2019) Risk-reducing medications for primary breast cancer: a network meta-analysis. Cochrane Database of Systematic Reviews 2019:4.
Crossref
Haifa Maalmi, Viola Walter, Lina Jansen, Robert Owen, Alexis Ulrich, Ben Schöttker, Jenny Chang-Claude, Michael Hoffmeister & Hermann Brenner. (2018) Dose-Response Relationship between Serum Retinol Levels and Survival in Patients with Colorectal Cancer: Results from the DACHS Study. Nutrients 10:4, pages 510.
Crossref
Sang-Min Jeon & Eun-Ae Shin. (2018) Exploring vitamin D metabolism and function in cancer. Experimental & Molecular Medicine 50:4, pages 1-14.
Crossref
Monica Schroll, Katelyn Ludwig, Kerry Bauer & Amanda Hummon. (2018) Calcitriol Supplementation Causes Decreases in Tumorigenic Proteins and Different Proteomic and Metabolomic Signatures in Right versus Left-Sided Colon Cancer. Metabolites 8:1, pages 5.
Crossref
Marjolein van Driel, Johannes P.T.M. van Leeuwen, Alberto Muñoz & David Feldman. 2018. Vitamin D. Vitamin D 711 742 .
Sarah Beaudin & JoEllen Welsh. (2017) 1,25-Dihydroxyvitamin D Regulation of Glutamine Synthetase and Glutamine Metabolism in Human Mammary Epithelial Cells. Endocrinology 158:12, pages 4174-4188.
Crossref
Haifa Maalmi, Viola Walter, Lina Jansen, Jenny Chang-Claude, Robert W. Owen, Alexis Ulrich, Ben Schöttker, Michael Hoffmeister & Hermann Brenner. (2017) Relationship of very low serum 25-hydroxyvitamin D3 levels with long-term survival in a large cohort of colorectal cancer patients from Germany. European Journal of Epidemiology 32:11, pages 961-971.
Crossref
Lukasz Laczmanski, Felicja Lwow, Anna Osina, Martyna Kepska, Izabela Laczmanska & Wojciech Witkiewicz. (2017) Association of the vitamin D receptor FokI gene polymorphism with sex- and non-sex-associated cancers: A meta-analysis . Tumor Biology 39:10, pages 101042831772716.
Crossref
Luciana Bohl, Solange Guizzardi, Valeria Rodríguez, Lucila Hinrichsen, Viviana Rozados, David Cremonezzi, Nori Tolosa de Talamoni & Gabriela Picotto. (2017) Combined calcitriol and menadione reduces experimental murine triple negative breast tumor. Biomedicine & Pharmacotherapy 94, pages 21-26.
Crossref
Shoujiro Ogawa, Hiroki Kittaka, Akiho Nakata, Kenji Komatsu, Takahiro Sugiura, Mamoru Satoh, Fumio Nomura & Tatsuya Higashi. (2017) Enhancing analysis throughput, sensitivity and specificity in LC/ESI–MS/MS assay of plasma 25-hydroxyvitamin D 3 by derivatization with triplex 4-(4-dimethylaminophenyl)-1,2,4-triazoline-3,5-dione (DAPTAD) isotopologues. Journal of Pharmaceutical and Biomedical Analysis 136, pages 126-133.
Crossref
Krista Y. Christensen, Michelle R. Raymond, Brooke A. Thompson & Henry A. Anderson. (2016) Fish Consumption, Levels of Nutrients and Contaminants, and Endocrine-Related Health Outcomes Among Older Male Anglers in Wisconsin. Journal of Occupational & Environmental Medicine 58:7, pages 668-675.
Crossref
Yeon Soo JungHee Jung KimSeok Kyo SeoYoung Sik ChoiEun Ji NamSunghoon KimSang Wun KimHyuck Dong HanJae Wook KimYoung Tae Kim. (2016) Anti-Proliferative and Apoptotic Activities of Müllerian Inhibiting Substance Combined with Calcitriol in Ovarian Cancer Cell Lines. Yonsei Medical Journal 57:1, pages 33.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.