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Original Article

Anti-osteoporotic activity of puerarin 6″-O-xyloside on ovariectomized mice and its potential mechanism

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Pages 111-117 | Received 25 Jun 2014, Accepted 06 Feb 2015, Published online: 10 Apr 2015

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Read on this site (4)

Saied A. Aboushanab, Shaimaa M. Khedr, Irina F. Gette, Irina G. Danilova, Natalia A. Kolberg, Gokare A. Ravishankar, Ranga Rao Ambati & Elena G. Kovaleva. (2023) Isoflavones derived from plant raw materials: bioavailability, anti-cancer, anti-aging potentials, and microbiome modulation. Critical Reviews in Food Science and Nutrition 63:2, pages 261-287.
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Yanran Yang, Daiyun Chen, Yilin Li, Jinghua Zou, Ruiqi Han, Hongkun Li & Jun Zhang. (2022) Effect of Puerarin on Osteogenic Differentiation in vitro and on New Bone Formation in vivo. Drug Design, Development and Therapy 16, pages 2885-2900.
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Yun Zhou, Xiaoli Song & Gang Dong. (2019) Effects of verapamil on the pharmacokinetics of puerarin in rats. Xenobiotica 49:10, pages 1178-1182.
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Lu Liu, Pihong Li, Lujun Qiao & Xiaohua Li. (2019) Effects of astragaloside IV on the pharmacokinetics of puerarin in rats. Xenobiotica 49:10, pages 1173-1177.
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Articles from other publishers (15)

Dong-min Cao & Tao Liu. (2023) Identification of Active Compounds of Pueraria Lobata and their Mechanisms of Action by LC-MS/MS and Network Pharmacology. Current Chinese Science 3:5, pages 398-406.
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Yanhai Xi, Weiheng Wang, Ning Xu, Changgui Shi, Guohua Xu, Jinxing Sun, Hailong He & Tingwang Jiang. (2022) Myricetin Loaded Nano-micelles Delivery System Reduces Bone Loss Induced by Ovariectomy in Rats Through Inhibition of Osteoclast Formation. Journal of Pharmaceutical Sciences 111:8, pages 2341-2352.
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Bojia Liu, Xinxin Liu, Qing Ning, Rongling Zhong, Zhi Xia, Jiayan Li, Jie Song & Yingjie Wei. (2020) Evaluation of toxicity and anti-osteoporosis effect in rats treated with the flavonoids of Psoraleae Fructus. Journal of Functional Foods 75, pages 104262.
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Long Li, Jun‐Dong Liu, Guo‐Dong Gao, Kai Zhang, Yu‐Wei Song & Hong‐Bo Li. (2020) Puerarin 6″‐O‐xyloside suppressed HCC via regulating proliferation, stemness, and apoptosis with inhibited PI3K/AKT/mTOR. Cancer Medicine 9:17, pages 6399-6410.
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Xiaomei Tao, Yefeng Yin, Dongbo Lian, Hongyan Gu, Wen Chen, Lu Yang, Gang Yin, Pengfei Liu, Lili Li, Yuanyuan Wei, Zhengzheng Xie, Fei Liu, Hangshuo Sui, Dan Yan & Weiwei Tao. (2020) Puerarin 6″‐O‐xyloside suppresses growth, self‐renewal and invasion of lung cancer stem‐like cells derived from A549 cells via regulating Akt/c‐Myc signalling. Clinical and Experimental Pharmacology and Physiology 47:7, pages 1311-1319.
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Siming Zhou, Zhengbo Tao, Yue Zhu & Lin Tao. (2019) Mapping theme trends and recognizing hot spots in postmenopausal osteoporosis research: a bibliometric analysis. PeerJ 7, pages e8145.
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Jianbo He, Xiaojuan Li, Ziyi Wang, Samuel Bennett, Kai Chen, Zhifeng Xiao, Jiheng Zhan, Shudong Chen, Yu Hou, Junhao Chen, Shaofang Wang, Jiake Xu & Dingkun Lin. (2019) Therapeutic Anabolic and Anticatabolic Benefits of Natural Chinese Medicines for the Treatment of Osteoporosis. Frontiers in Pharmacology 10.
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Da-Eun KimJeon-Kyung KimSang-Kap HanSe-Eun JangMyung Joo HanDong-Hyun Kim. (2019) Lactobacillus plantarum NK3 and Bifidobacterium longum NK49 Alleviate Bacterial Vaginosis and Osteoporosis in Mice by Suppressing NF- κ B-Linked TNF- α Expression . Journal of Medicinal Food 22:10, pages 1022-1031.
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Byungsu Ahn, Sueun Lee, Sohi Kang, Changjong Moon, Jong-Choon Kim, Jong-Sik Jang & Sung-Ho Kim. (2018) The effect of Puerariae Radix on ovariectomy-induced bone loss in C3H/HeN mice. Journal of Biomedical Translational Research 19:4, pages 73-78.
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Xiangwei Zeng, Qian Feng, Fengming Zhao, Chao Sun, Tao Zhou, Jing Yang & Xiuqin Zhan. (2018) Puerarin inhibits TRPM3/miR-204 to promote MC3T3-E1 cells proliferation, differentiation and mineralization. Phytotherapy Research 32:6, pages 996-1003.
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Çiğdem Coşkun Türer, Akif Türer, Mustafa Cenk Durmuşlar & Mehmet Emin Önger. (2017) The Local Effect of Puerarin on Critical-Sized Calvarial Defects. Journal of Craniofacial Surgery 28:1, pages 143-146.
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Qi‑Lin Zhou, Ru‑Zi Qin, Yan‑Xin Yang, Kun‑Bing Huang & Xian‑Wen Yang. (2016) Polydatin possesses notable anti‑osteoporotic activity via regulation of OPG, RANKL and β‑catenin. Molecular Medicine Reports.
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Zhiguo Zhang, Qiaoyan Zhang, Hua Yang, Wei Liu, Naidan Zhang, Luping Qin & Hailiang Xin. (2016) Monotropein isolated from the roots of Morinda officinalis increases osteoblastic bone formation and prevents bone loss in ovariectomized mice. Fitoterapia 110, pages 166-172.
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Chun-Tao Che, Man Wong & Christopher Lam. (2016) Natural Products from Chinese Medicines with Potential Benefits to Bone Health. Molecules 21:3, pages 239.
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Yun Zhang, Ming Yan, Qing-feng Yu, Pei-fan Yang, Hai-dong Zhang, Yong-hong Sun, Zhi-fen Zhang & Yun-feng Gao. (2016) Puerarin Prevents LPS-Induced Osteoclast Formation and Bone Loss <i>via</i> Inhibition of Akt Activation. Biological & Pharmaceutical Bulletin Biological and Pharmaceutical Bulletin 39:12, pages 2028-2035.
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