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Cytotherapy Volume 11, 2009 - Issue 7
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Research Article

Ex vivo-expanded autologous bone marrow-derived mesenchymal stromal cells in human spinal cord injury/paraplegia: a pilot clinical study

Rakhi Pal Stempeutics Research Private Ltd, Bangalore, India; Rakhi Pal and Nilam K. Venkataramana contributed equally.
,
Neelam K. Venkataramana Advanced Neuroscience Institute, BGS Global Hospitals, Bangalore, India; Rakhi Pal and Nilam K. Venkataramana contributed equally.Correspondence[email protected] [email protected]
,
Abhilash Bansal Manipal Hospital, Bangalore, India
,
Sudheer Balaraju Stempeutics Research Private Ltd, Bangalore, India
,
Majahar Jan Stempeutics Research Private Ltd, Bangalore, India
,
Ravi Chandra Manipal Hospital, Bangalore, India
,
Ashish Dixit Manipal Hospital, Bangalore, India
,
Amit Rauthan Manipal Hospital, Bangalore, India
,
Uday Murgod Manipal Hospital, Bangalore, India
&
Satish Totey Stempeutics Research Private Ltd, Bangalore, IndiaCorrespondence[email protected] [email protected]
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Pages 897-911 | Published online: 10 Nov 2009

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Yingyu Zhang, Jiebing Gu, Xiaoshuang Wang, Linfang Li, Lingling Fu, Di Wang, Xiuting Wang & Xuemei Han. (2023) Opportunities and challenges: mesenchymal stem cells in the treatment of multiple sclerosis. International Journal of Neuroscience 133:9, pages 1031-1044.
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Rumena Petkova, Nikolai Zhelev, Roumen Pankov & Stoyan Chakarov. (2018) Individual capacity for repair of DNA damage and potential uses of stem cell lines for clinical applications: a matter of (genomic) integrity. Biotechnology & Biotechnological Equipment 32:6, pages 1352-1358.
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Chao Xu, Feng Fu, Xiaohong Li & Sai Zhang. (2017) Mesenchymal stem cells maintain the microenvironment of central nervous system by regulating the polarization of macrophages/microglia after traumatic brain injury. International Journal of Neuroscience 127:12, pages 1124-1135.
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Jie Yang, Xianying Wang, Sha Liu & Gai Xue. (2016) BDNF expression is up-regulated by progesterone in human umbilical cord mesenchymal stem cells. Neurological Research 38:12, pages 1088-1093.
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Junseok W. Hur, Tai-Hyoung Cho, Dong-Hyuk Park, Jang-Bo Lee, Jung-Yul Park & Yong-Gu Chung. (2016) Intrathecal transplantation of autologous adipose-derived mesenchymal stem cells for treating spinal cord injury: A human trial. The Journal of Spinal Cord Medicine 39:6, pages 655-664.
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Vidyasagar Devaprasad Dedeepiya, Justin Benjamin William, Jutty KBC Parthiban, Ranganathan Chidambaram, Madasamy Balamurugan, Satoshi Kuroda, Masaru Iwasaki, Senthilkumar Preethy & Samuel JK Abraham. (2014) The known-unknowns in spinal cord injury, with emphasis on cell-based therapies – a review with suggestive arenas for research. Expert Opinion on Biological Therapy 14:5, pages 617-634.
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Indrani Datta, Swati Mishra, Lipsa Mohanty, Sunitha Pulikkot & Preeti G. Joshi. (2011) Neuronal plasticity of human Wharton's jelly mesenchymal stromal cells to the dopaminergic cell type compared with human bone marrow mesenchymal stromal cells. Cytotherapy 13:8, pages 918-932.
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Jin Wang, Lianming Liao & Jianming Tan. (2011) Mesenchymal-stem-cell-based experimental and clinical trials: current status and open questions. Expert Opinion on Biological Therapy 11:7, pages 893-909.
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Jose Maria Miranda-Sayago, Nieves Fernández-Arcas, Carmen Benito, Armando Reyes-Engel, Jorge Carrera & Antonio Alonso. (2011) Lifespan of human amniotic fluid-derived multipotent mesenchymal stromal cells. Cytotherapy 13:5, pages 572-581.
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John C Gensel, Dustin J Donnelly & Phillip G Popovich. (2011) Spinal cord injury therapies in humans: an overview of current clinical trials and their potential effects on intrinsic CNS macrophages. Expert Opinion on Therapeutic Targets 15:4, pages 505-518.
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Rakhi Pal, Chaitanya Gopinath, Nagesh M Rao, Poulomi Banerjee, Venkatesh Krishnamoorthy, Neelam K. Venkataramana & Satish Totey. (2010) Functional recovery after transplantation of bone marrow-derived human mesenchymal stromal cells in a rat model of spinal cord injury. Cytotherapy 12:6, pages 792-806.
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