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Research Article

Identification of aldehyde dehydrogenase 1A1 modulators using virtual screening

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Pages 489-494 | Received 10 Nov 2011, Accepted 20 Dec 2011, Published online: 01 Mar 2012

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Thomas Münzel & Andreas Daiber. (2018) The potential of aldehyde dehydrogenase 2 as a therapeutic target in cardiovascular disease. Expert Opinion on Therapeutic Targets 22:3, pages 217-231.
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Paul Anthony Martinez, Vanessa Elia Martinez, Sheela Rani, Meredith Murrell, Martin Javors, Jonathan Gelfond, Jonathan Alan Doorn, Elizabeth Fernandez & Randy Strong. (2023) Impaired aldehyde detoxification exacerbates motor deficits in an alpha‐synuclein mouse model of Parkinson's disease. Brain and Behavior.
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Josy Augustine, Evan P. Troendle, Peter Barabas, Corey A. McAleese, Thomas Friedel, Alan W. Stitt & Tim M. Curtis. (2021) The Role of Lipoxidation in the Pathogenesis of Diabetic Retinopathy. Frontiers in Endocrinology 11.
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Romina Deza-Ponzio, Macarena Lorena Herrera, María José Bellini, Miriam Beatriz Virgolini & Claudia Beatriz Hereñú. (2018) Aldehyde dehydrogenase 2 in the spotlight: The link between mitochondria and neurodegeneration. NeuroToxicology 68, pages 19-24.
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Gina D. Kusuma, Mohamed H. Abumaree, Anthony V. Perkins, Shaun P. Brennecke & Bill Kalionis. (2017) Reduced aldehyde dehydrogenase expression in preeclamptic decidual mesenchymal stem/stromal cells is restored by aldehyde dehydrogenase agonists. Scientific Reports 7:1.
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M.G. Holyavka, M.S. Kondratyev, A.A. Samchenko, A.V. Kabanov, V.M. Komarov & V.G. Artyukhov. (2016) In silico design of high-affinity ligands for the immobilization of inulinase. Computers in Biology and Medicine 71, pages 198-204.
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Edna Grünblatt & Peter Riederer. (2014) Aldehyde dehydrogenase (ALDH) in Alzheimer’s and Parkinson’s disease. Journal of Neural Transmission 123:2, pages 83-90.
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Ching-Chi Chiu, Tu-Hsueh Yeh, Szu-Chia Lai, Yah-Huei Wu-Chou, Che-Hong Chen, Daria Mochly-Rosen, Yin-Cheng Huang, Yu-Jie Chen, Chao-Lang Chen, Ya-Ming Chang, Hung-Li Wang & Chin-Song Lu. (2015) Neuroprotective effects of aldehyde dehydrogenase 2 activation in rotenone-induced cellular and animal models of parkinsonism. Experimental Neurology 263, pages 244-253.
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Javier A. Belmont-Díaz, Luis F. Calleja-Castañeda, Belem Yoval-Sánchez & José S. Rodríguez-Zavala. (2015) Tamoxifen, an anticancer drug, is an activator of human aldehyde dehydrogenase 1A1. Proteins: Structure, Function, and Bioinformatics 83:1, pages 105-116.
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