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Review Article

Topoisomerase as target for antibacterial and anticancer drug discovery

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Pages 419-435 | Received 29 Dec 2011, Accepted 16 Jan 2012, Published online: 01 Mar 2012

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Hadeer K. Swedan, Asmaa E. Kassab, Ehab M. Gedawy & Salwa E. Elmeligie. (2023) Design, synthesis, and biological evaluation of novel ciprofloxacin derivatives as potential anticancer agents targeting topoisomerase II enzyme. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1, pages 118-137.
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Valeria Visone, Ildikó Szabó, Giuseppe Perugino, Ferenc Hudecz, Zoltán Bánóczi & Anna Valenti. (2020) Topoisomerases inhibition and DNA binding mode of daunomycin–oligoarginine conjugate. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 1363-1371.
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Samia S. Hawas, Nadia S. El-Gohary, Moustafa T. Gabr, Mona I. Shaaban & Mahmoud B. El-Ashmawy. (2019) Synthesis, molecular docking, antimicrobial, antiquorum-sensing and antiproliferative activities of new series of pyrazolo[3,4-b]pyridine analogs. Synthetic Communications 49:19, pages 2466-2487.
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Zhaoqi Yang, Tuoyu Jiang, Hanshi Zhong & Yu Kang. (2018) Bulge oligonucleotide as an inhibitory agent of bacterial topoisomerase I. Journal of Enzyme Inhibition and Medicinal Chemistry 33:1, pages 319-323.
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Raed A. Al-Qawasmeh, Mohammed M. Abadleh, Jalal A. Zahra, Mustafa M. El-Abadelah, Rabab Albashiti, Franca Zani, Matteo Incerti & Paola Vicini. (2014) Design synthesis and antibacterial activity studies of new thiadiazoloquinolone compounds. Journal of Enzyme Inhibition and Medicinal Chemistry 29:6, pages 777-785.
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