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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 29, 2014 - Issue 3
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Research Article

Discovery of a series of small molecules as potent histone deacetylase inhibitors

Lei ZhangDepartment of Medicinal Chemistry, School of Pharmacy, Shandong University Jinan, ShandongChina
,
Xuejian WangSchool of Pharmacy and Biology Science, Weifang Medicinal University Weifang, ShandongChina
,
Xiaoguang LiDepartment of Medicinal Chemistry, School of Pharmacy, Shandong University Jinan, ShandongChina
&
Wenfang XuDepartment of Medicinal Chemistry, School of Pharmacy, Shandong University Jinan, ShandongChinaCorrespondence[email protected]
Pages 333-337 | Received 31 Jan 2013, Accepted 24 Feb 2013, Published online: 27 Mar 2013

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Yingjie Zhang, Xiaoguang Li, Jinning Hou, Yongxue Huang & Wenfang Xu. (2015) Design, synthesis, and antitumor evaluation of histone deacetylase inhibitors with l-phenylglycine scaffold. Drug Design, Development and Therapy 9, pages 5553-5567.
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Articles from other publishers (9)

Chunhui Jiang, Xuefei Sha, Cheng Ni, Wei Qin, Xuejie Zhu, Shan Wang, Xuan Li & Hongfei Lu. (2022) Visible-Light-Promoted Cross Dehydrogenative/Decarboxylative Coupling Cascades of Glycine Ester Derivatives and β-Keto Acids. The Journal of Organic Chemistry 87:13, pages 8744-8751.
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Xue Niu, Hong Zhang, Chengzhi Zhang, Li Dou & Zhibing Wu. (2022) Design, Synthesis and in Vitro Antifungal Mechanism of Novel Phenylalanine Derivatives . Chemistry & Biodiversity 19:6.
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Reyaz Hassan Mir, Roohi Mohi-ud-din, Taha Umair Wani, Mohammad Ovais Dar, Abdul Jaleel Shah, Bashir Lone, Chawla Pooja & Mubashir Hussain Masoodi. (2021) Indole: A Privileged Heterocyclic Moiety in the Management of Cancer. Current Organic Chemistry 25:6, pages 724-736.
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Shilin Li, Xiaorong Yang, Yunwei Wang, Huang Zhou, Boyang Zhang, Ganxing Huang, Yuan Zhang & Ying Li. (2018) Visible Light-Induced Aerobic Oxidative Csp3 −H Arylation of Glycine Derivatives. Advanced Synthesis & Catalysis 360:22, pages 4452-4456.
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Sakineh Dadashpour & Saeed Emami. (2018) Indole in the target-based design of anticancer agents: A versatile scaffold with diverse mechanisms. European Journal of Medicinal Chemistry 150, pages 9-29.
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Yuanyuan Wei, Jie Wang, Yajun Wang, Xiaoqiang Yao, Caixia Yang & Congde Huo. (2018) Auto-oxidation promoted sp 3 C–H arylation of glycine derivatives . Organic & Biomolecular Chemistry 16:27, pages 4985-4989.
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Yan-xin Huang, Jian Zhao, Qiu-hang Song, Li-hua Zheng, Cong Fan, Ting-ting Liu, Yong-li Bao, Lu-guo Sun, Li-biao Zhang & Yu-xin Li. (2016) Virtual screening and experimental validation of novel histone deacetylase inhibitors. BMC Pharmacology and Toxicology 17:1.
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Xiaoyang Li, Jingde Wu, Xiaoguang Li, Weiwei Mu, Xueliang Liu, Yiming Jin, Wenfang Xu & Yingjie Zhang. (2015) Development of N-hydroxybenzamide derivatives with indole-containing cap group as histone deacetylases inhibitors. Bioorganic & Medicinal Chemistry 23:19, pages 6258-6270.
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Federico Andreoli & Alberto Del Rio. (2015) Computer-aided Molecular Design of Compounds Targeting Histone Modifying Enzymes. Computational and Structural Biotechnology Journal 13, pages 358-365.
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