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Research Article

Anti-cancer and anti-hepatitis C virus NS5B polymerase activity of etodolac 1,2,4-triazoles

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Pages 778-785 | Received 04 Jul 2014, Accepted 29 Sep 2014, Published online: 27 Aug 2015

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Xian-yu Sun, Chun-yan Zhong, Qing-qing Qiu, Zhen-wang Li, Mei-yu Liu, Xin Wang & Cheng-hao Jin. (2019) Synthesis, activity evaluation, and pro-apoptotic properties of novel 1,2,4-triazol-3-amine derivatives as potent anti-lung cancer agents. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 1210-1217.
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Ferah Comert Onder, Pinar Siyah, Serdar Durdagi, Mehmet Ay & Bulent Ozpolat. (2022) Novel etodolac derivatives as eukaryotic elongation factor 2 kinase (eEF2K) inhibitors for targeted cancer therapy. RSC Medicinal Chemistry 13:7, pages 840-849.
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Han Zhang, Xin Zheng, Jichong Li, Qingbo Liu, Xiao-Xiao Huang, Huaiwei Ding, Ryosuke Suzuki, Masamichi Muramatsu & Shao-Jiang Song. (2021) Flavonoid-triazolyl hybrids as potential anti-hepatitis C virus agents: Synthesis and biological evaluation. European Journal of Medicinal Chemistry 218, pages 113395.
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S. A. El‐Sebaey. (2020) Recent Advances in 1,2,4‐Triazole Scaffolds as Antiviral Agents. ChemistrySelect 5:37, pages 11654-11680.
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Xiaoyue Wen, Yongqin Zhou, Junhao Zeng & Xinyue Liu. (2020) Recent Development of 1,2,4-triazole-containing Compounds as Anticancer Agents. Current Topics in Medicinal Chemistry 20:16, pages 1441-1460.
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Monika Pitucha, Monika Janeczko, Katarzyna Klimek, Emilia Fornal, Maciej Wos, Anna Pachuta-Stec, Grazyna Ginalska & Agnieszka A. Kaczor. (2020) 1,2,4-Triazolin-5-thione derivatives with anticancer activity as CK1γ kinase inhibitors. Bioorganic Chemistry 99, pages 103806.
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Muhammed İ. Han, Hatice Bekçi, Abdullahi I. Uba, Yeliz Yıldırım, Ercüment Karasulu, Ahmet Cumaoğlu, Hatice Y. Karasulu, Kemal Yelekçi, Özgür Yılmaz & Ş. Güniz Küçükgüzel. (2019) Synthesis, molecular modeling, in vivo study, and anticancer activity of 1,2,4‐triazole containing hydrazide–hydrazones derived from ( S )‐naproxen . Archiv der Pharmazie 352:6, pages 1800365.
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Bhaskar Kummari, Perla Ramesh, Rayam Parsharamulu, Tejeswara Rao Allaka, Hasithashilpa Anantaraju, Perumal Yogeeswari, Sridhar Balasubramanian, Sravanthi Devi Guggilapu, Bathini Nagendra Babu & Jaya Shree Anireddy. (2018) Design and Synthesis of New Etodolac‐Pyridazinones as Potent Anticancer Agents Using Pb(OAc) 4 to Assist N‐N Bond Formation . ChemistrySelect 3:18, pages 5050-5054.
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Işıl Çoruh, Özge Çevik, Kemal Yelekçi, Teodora Djikic & Ş. Güniz Küçükgüzel. (2018) Synthesis, anticancer activity, and molecular modeling of etodolac-thioether derivatives as potent methionine aminopeptidase (type II) inhibitors. Archiv der Pharmazie 351:3-4, pages 1700195.
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Shilpa M. Somagond, Ravindra R. Kamble, Pramod P. Kattimani, Saba Kauser J. Shaikh, Sheshagiri R. Dixit, Shrinivas D. Joshi & Hirihalli C. Devarajegowda. (2018) Design, Docking, and Synthesis of Quinoline‐2 H ‐1,2,4‐triazol‐3(4 H )‐ones as Potent Anticancer and Antitubercular Agents . ChemistrySelect 3:7, pages 2004-2016.
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Mohammed M. Abadleh, Mustafa M. El-Abadelah & Monther S. Zreid. (2018) One-Pot Synthesis of Model 1H,1'H-5,5'-Bi(1,2,4-Triazoles). HETEROCYCLES 96:6, pages 1080.
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Mahnaz Farahi, Bahador Karami, Zohreh Banaki, Fatemeh Rastgoo & Khalil Eskandari. (2017) TSA-catalyzed regioselective synthesis of medicinally important 4-aryl-substituted dihydropyrimidine derivatives fused to pyrazole and triazole scaffolds via an efficient and green Domino reaction. Monatshefte für Chemie - Chemical Monthly 148:8, pages 1469-1475.
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Necla Kulabaş, Esra Tatar, Özlem Bingöl Özakpınar, Derya Özsavcı, Christophe Pannecouque, Erik De Clercq & İlkay Küçükgüzel. (2016) Synthesis and antiproliferative evaluation of novel 2-(4H-1,2,4-triazole-3-ylthio)acetamide derivatives as inducers of apoptosis in cancer cells. European Journal of Medicinal Chemistry 121, pages 58-70.
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Sevil Şenkardeş, Neerja Kaushik-Basu, İrem Durmaz, Dinesh Manvar, Amartya Basu, Rengül Atalay & Ş. Güniz Küçükgüzel. (2016) Synthesis of novel diflunisal hydrazide–hydrazones as anti-hepatitis C virus agents and hepatocellular carcinoma inhibitors. European Journal of Medicinal Chemistry 108, pages 301-308.
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Ş.Güniz Küçükgüzel & Pelin Çıkla-Süzgün. (2015) Recent advances bioactive 1,2,4-triazole-3-thiones. European Journal of Medicinal Chemistry 97, pages 830-870.
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