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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 31, 2016 - Issue 2
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Research Article

Synthesis and inhibition potency of novel ureido benzenesulfonamides incorporating GABA as tumor-associated carbonic anhydrase IX and XII inhibitors

Mariangela CerusoDipartimento di Chimica, Laboratorio di Chimica Bioinorganica, Università degli Studi di Firenze, Sesto Fiorentino (Firenze), Italy and Correspondence[email protected]
,
Sabrina AntelDipartimento di Chimica, Laboratorio di Chimica Bioinorganica, Università degli Studi di Firenze, Sesto Fiorentino (Firenze), Italy and
,
Andrea ScozzafavaDipartimento di Chimica, Laboratorio di Chimica Bioinorganica, Università degli Studi di Firenze, Sesto Fiorentino (Firenze), Italy and
&
Claudiu T. SupuranNeurofarba Department, Università degli Studi di Firenze, Sesto Fiorentino (Florence), ItalyCorrespondence[email protected]
Pages 205-211 | Received 13 Jan 2015, Accepted 27 Jan 2015, Published online: 20 Mar 2015

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E. Nazarshodeh, R. Sheikhpour, S. Gharaghani & M. A. Sarram. (2018) A novel proteochemometrics model for predicting the inhibition of nine carbonic anhydrase isoforms based on supervised Laplacian score and k-nearest neighbour regression. SAR and QSAR in Environmental Research 29:6, pages 419-437.
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Elif Unluer, Halise Inci Gul, Alkan Demirtas, Hiroshi Sakagami, Naoki Umemura, Muhammet Tanc, Cavit Kazaz & Claudiu T. Supuran. (2016) Synthesis and bioactivity studies of 1-aryl-3-(2-hydroxyethylthio)-1-propanones. Journal of Enzyme Inhibition and Medicinal Chemistry 31:sup3, pages 105-109.
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Emin Garibov, Parham Taslimi, Afsun Sujayev, Zeynebe Bingol, Songul Çetinkaya, İlhami Gulçin, Sukru Beydemir, Vagif Farzaliyev, Saleh H. Alwasel & Claudiu T. Supuran. (2016) Synthesis of 4,5-disubstituted-2-thioxo-1,2,3,4-tetrahydropyrimidines and investigation of their acetylcholinesterase, butyrylcholinesterase, carbonic anhydrase I/II inhibitory and antioxidant activities. Journal of Enzyme Inhibition and Medicinal Chemistry 31:sup3, pages 1-9.
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Articles from other publishers (10)

Mária Bodnár Mikulová, Dáša Kružlicová, Daniel Pecher, Claudiu T. Supuran & Peter Mikuš. (2020) Synthetic Strategies and Computational Inhibition Activity Study for Triazinyl-Substituted Benzenesulfonamide Conjugates with Polar and Hydrophobic Amino Acids as Inhibitors of Carbonic Anhydrases. International Journal of Molecular Sciences 21:10, pages 3661.
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Razieh Sheikhpour, Sajjad Gharaghani & Elmira Nazarshodeh. (2020) Sparse feature selection in multi-target modeling of carbonic anhydrase isoforms by exploiting shared information among multiple targets. Chemometrics and Intelligent Laboratory Systems 200, pages 104000.
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Majid Ali, Murat Bozdag, Umar Farooq, Andrea Angeli, Fabrizio Carta, Paola Berto, Giuseppe Zanotti & Claudiu T. Supuran. (2020) Benzylaminoethyureido-Tailed Benzenesulfonamides: Design, Synthesis, Kinetic and X-ray Investigations on Human Carbonic Anhydrases. International Journal of Molecular Sciences 21:7, pages 2560.
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Immo Serbian, Philipp Schwarzenberger, Anne Loesche, Sophie Hoenke, Ahmed Al-Harrasi & René Csuk. (2019) Ureidobenzenesulfonamides as efficient inhibitors of carbonic anhydrase II. Bioorganic Chemistry 91, pages 103123.
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Wagdy M. Eldehna, Mahmoud F. Abo-Ashour, Alessio Nocentini, Radwan S. El-Haggar, Silvia Bua, Alessandro Bonardi, Sara T. Al-Rashood, Ghada S. Hassan, Paola Gratteri, Hatem A. Abdel-Aziz & Claudiu T. Supuran. (2019) Enhancement of the tail hydrophobic interactions within the carbonic anhydrase IX active site via structural extension: Design and synthesis of novel N-substituted isatins-SLC-0111 hybrids as carbonic anhydrase inhibitors and antitumor agents. European Journal of Medicinal Chemistry 162, pages 147-160.
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Claudiu T. Supuran, Vincenzo Alterio, Anna Di Fiore, Katia D’ Ambrosio, Fabrizio Carta, Simona Maria Monti & Giuseppina De Simone. (2018) Inhibition of carbonic anhydrase IX targets primary tumors, metastases, and cancer stem cells: Three for the price of one. Medicinal Research Reviews 38:6, pages 1799-1836.
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Alparslan AtahanNahit GencerCigdem BilenEmre YavuzHayriye GencFatih SonmezMustafa ZenginMustafa CeylanMustafa Kucukislamoglu. (2018) Synthesis, Biological Activity and Structure-Activity Relationship of Novel Diphenylurea Derivatives Containing Tetrahydroquinoline as Carbonic Anhydrase I and II Inhibitors. ChemistrySelect 3:2, pages 529-534.
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Wagdy M. Eldehna, Ghada H. Al-Ansary, Silvia Bua, Alessio Nocentini, Paola Gratteri, Ayman Altoukhy, Hazem Ghabbour, Hanaa Y. Ahmed & Claudiu T. Supuran. (2017) Novel indolin-2-one-based sulfonamides as carbonic anhydrase inhibitors: Synthesis, in vitro biological evaluation against carbonic anhydrases isoforms I, II, IV and VII and molecular docking studies. European Journal of Medicinal Chemistry 127, pages 521-530.
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Wagdy M. Eldehna, Mohamed Fares, Mariangela Ceruso, Hazem A. Ghabbour, Sahar M. Abou-Seri, Hatem A. Abdel-Aziz, Dalal A. Abou El Ella & Claudiu T. Supuran. (2016) Amido/ureidosubstituted benzenesulfonamides-isatin conjugates as low nanomolar/subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform XII. European Journal of Medicinal Chemistry 110, pages 259-266.
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Benedetta Cornelio, Marie Laronze-Cochard, Mariangela Ceruso, Marta Ferraroni, Graham A. RanceFabrizio Carta, Andrei N. KhlobystovAntonella Fontana, Claudiu T. Supuran & Janos Sapi. (2016) 4-Arylbenzenesulfonamides as Human Carbonic Anhydrase Inhibitors (hCAIs): Synthesis by Pd Nanocatalyst-Mediated Suzuki–Miyaura Reaction, Enzyme Inhibition, and X-ray Crystallographic Studies. Journal of Medicinal Chemistry 59:2, pages 721-732.
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