2,418
Views
27
CrossRef citations to date
0
Altmetric
Research Article

In vitro effects of some flavonoids and phenolic acids on human pyruvate kinase isoenzyme M2

, &
Pages 314-317 | Received 25 Dec 2014, Accepted 16 Feb 2015, Published online: 23 Mar 2015

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Veysel Comakli, Sevki Adem, Aykut Oztekin & Ramazan Demirdag. (2022) Screening inhibitory effects of selected flavonoids on human recombinant aldose reductase enzyme: in vitro and in silico study. Archives of Physiology and Biochemistry 128:5, pages 1368-1374.
Read now
Sevki Adem, Veysel Comakli & Naim Uzun. (2018) Pyruvate kinase activators as a therapy target: a patent review 2011-2017. Expert Opinion on Therapeutic Patents 28:1, pages 61-68.
Read now
Gang Wang, Jun-Jie Wang, Rui Guan, Li Du, Jing Gao & Xing-Li Fu. (2017) Strategies to Target Glucose Metabolism in Tumor Microenvironment on Cancer by Flavonoids. Nutrition and Cancer 69:4, pages 534-554.
Read now

Articles from other publishers (24)

Flama Monteiro, Shilpa S. Shetty & Suchetha Kumari N. (2023) Natural antioxidants as inhibitors of pyruvate kinase M2 in Warburg phenotypes. Journal of Herbal Medicine 42, pages 100750.
Crossref
Layanne Nascimento Fraga, Dragan Milenkovic, Sara Lima Anacleto, Michelle Salemi, Franco Maria Lajolo & Neuza Mariko Aymoto Hassimotto. (2023) Citrus flavanone metabolites significantly modulate global proteomic profile in pancreatic β-cells under high-glucose-induced metabolic stress. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1871:3, pages 140898.
Crossref
Umberto Maria Battisti, Chunixa Gao, Fady Akladios, Woonghee Kim, Hong Yang, Cemil Bayram, Ismail Bolat, Metin Kiliclioglu, Nursena Yuksel, Ozlem Ozdemir Tozlu, Cheng Zhang, Jihad Sebhaoui, Shazia Iqbal, Saeed Shoaie, Ahmet Hacimuftuoglu, Serkan Yildirim, Hasan Turkez, Mathias Uhlen, Jan Boren, Adil Mardinoglu & Morten Grøtli. (2023) Ellagic Acid and Its Metabolites as Potent and Selective Allosteric Inhibitors of Liver Pyruvate Kinase. Nutrients 15:3, pages 577.
Crossref
Yi Zhang, Qiong Li, Zhao Huang, Bowen Li, Edouard C. Nice, Canhua Huang, Liuya Wei & Bingwen Zou. (2022) Targeting Glucose Metabolism Enzymes in Cancer Treatment: Current and Emerging Strategies. Cancers 14:19, pages 4568.
Crossref
Sahil Arora, Gaurav Joshi, Anuhar Chaturvedi, Michael Heuser, Santoshkumar Patil & Raj Kumar. (2021) A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate Kinase M2. Journal of Medicinal Chemistry 65:2, pages 1171-1205.
Crossref
Iqra Sarfraz, Azhar Rasul, Ilknur Ucak, Ngit Shin Lai, Muhammad Asrar & Şevki Adem. 2022. Analytical Techniques in Biosciences. Analytical Techniques in Biosciences 191 199 .
Mayuri Dholaria. 2022. Handbook of Oxidative Stress in Cancer: Therapeutic Aspects. Handbook of Oxidative Stress in Cancer: Therapeutic Aspects 305 326 .
Bhagyashri Rathod, Shivam Chak, Sagarkumar Patel & Amit Shard. (2021) Tumor pyruvate kinase M2 modulators: a comprehensive account of activators and inhibitors as anticancer agents. RSC Medicinal Chemistry 12:7, pages 1121-1141.
Crossref
Luis Gustavo Saboia Ponte, Isadora Carolina Betim Pavan, Mariana Camargo Silva Mancini, Luiz Guilherme Salvino da Silva, Ana Paula Morelli, Matheus Brandemarte Severino, Rosangela Maria Neves Bezerra & Fernando Moreira Simabuco. (2021) The Hallmarks of Flavonoids in Cancer. Molecules 26:7, pages 2029.
Crossref
Marek Samec, Alena Liskova, Lenka Koklesova, Sandra Mersakova, Jan Strnadel, Karol Kajo, Martin Pec, Kevin Zhai, Karel Smejkal, Sepideh Mirzaei, Kiavash Hushmandi, Milad Ashrafizadeh, Luciano Saso, Aranka Brockmueller, Mehdi Shakibaei, Dietrich Büsselberg & Peter Kubatka. (2021) Flavonoids Targeting HIF-1: Implications on Cancer Metabolism. Cancers 13:1, pages 130.
Crossref
Mayuri Dholaria. 2021. Handbook of Oxidative Stress in Cancer: Therapeutic Aspects. Handbook of Oxidative Stress in Cancer: Therapeutic Aspects 1 22 .
Leonardo Di Donna, Lucia Bartella, Luciana De Vero, Maria Gullo, Angelo M. Giuffrè, Clotilde Zappia, Marco Capocasale, Marco Poiana, Silvia D’Urso & Andrea Caridi. (2020) Vinegar production from Citrus bergamia by-products and preservation of bioactive compounds. European Food Research and Technology 246:10, pages 1981-1990.
Crossref
Marek Samec, Alena Liskova, Lenka Koklesova, Samson Mathews Samuel, Kevin Zhai, Constanze Buhrmann, Elizabeth Varghese, Mariam Abotaleb, Tawar Qaradakhi, Anthony Zulli, Martin Kello, Jan Mojzis, Pavol Zubor, Taeg Kyu Kwon, Mehdi Shakibaei, Dietrich Büsselberg, Gustavo R. Sarria, Olga Golubnitschaja & Peter Kubatka. (2020) Flavonoids against the Warburg phenotype—concepts of predictive, preventive and personalised medicine to cut the Gordian knot of cancer cell metabolism. EPMA Journal 11:3, pages 377-398.
Crossref
Muhammad Shoaib Ali Gill, Hammad Saleem & Nafees Ahemad. (2020) Plant Extracts and their Secondary Metabolites as Modulators of Kinases. Current Topics in Medicinal Chemistry 20:12, pages 1093-1104.
Crossref
Suresh Chandra Phulara, Nazia Ahmad, Bidyut Mazumdar & Vikrant Singh Rajput. 2020. Microbiological Advancements for Higher Altitude Agro-Ecosystems & Sustainability. Microbiological Advancements for Higher Altitude Agro-Ecosystems & Sustainability 327 373 .
Marjorie Reyes-Farias & Catalina Carrasco-Pozo. (2019) The Anti-Cancer Effect of Quercetin: Molecular Implications in Cancer Metabolism. International Journal of Molecular Sciences 20:13, pages 3177.
Crossref
Catia S. Branco, Angela Duong, Alencar K. Machado, Gustavo Scola, Ana C. Andreazza & Mirian Salvador. (2019) Modulation of Mitochondrial and Epigenetic Targets by Polyphenols-rich Extract from Araucaria angustifolia in Larynx Carcinoma. Anti-Cancer Agents in Medicinal Chemistry 19:1, pages 130-139.
Crossref
Meenakshi Sudhakaran, Sagar Sardesai & Andrea I. Doseff. (2019) Flavonoids: New Frontier for Immuno-Regulation and Breast Cancer Control. Antioxidants 8:4, pages 103.
Crossref
Angelo M. Giuffrè, Clotilde Zappia, Marco Capocasale, Marco Poiana, Rossana Sidari, Leonardo Di Donna, Lucia Bartella, Giovanni Sindona, Giuseppe Corradini, Paolo Giudici & Andrea Caridi. (2018) Vinegar production to valorise Citrus bergamia by-products. European Food Research and Technology 245:3, pages 667-675.
Crossref
Matheus D. Baldissera, Carine F. Souza, Antônio Francisco Igor M. De Matos, Bernardo Baldisserotto, Aleksandro S. da Silva & Silvia G. Monteiro. (2018) Tissue oxidative damage mediates impairment on phosphotransfer network during thymol intake: Effects on hepatic and renal bioenergetics. Chemico-Biological Interactions 296, pages 83-88.
Crossref
Yixiao Shen, Haiyan Sun, Haiying Zeng, Witoon Prinyawiwatukul, Wenqing Xu & Zhimin Xu. (2018) Increases in Phenolic, Fatty Acid, and Phytosterol Contents and Anticancer Activities of Sweet Potato after Fermentation by Lactobacillus acidophilus . Journal of Agricultural and Food Chemistry 66:11, pages 2735-2741.
Crossref
Ana Elena Quirós Sauceda, Sonia Guadalupe Sáyago‐Ayerdi, Jesús Fernando Ayala‐Zavala, Abraham Wall‐Medrano, Laura A. de la Rosa*Gustavo A. González‐Aguilar*Emilio Álvarez‐Parrilla. 2017. Fruit and Vegetable Phytochemicals. Fruit and Vegetable Phytochemicals 125 138 .
Yaping Zhong, Yonggang Zhang, Ping Wang, Hongxiu Gao, Chunling Xu & Hui Li. (2016) V8 induces apoptosis and the endoplasmic reticulum stress response in human multiple myeloma RPMI 8226 cells via the PERK-eIF2α-ATF4 signaling pathway. Oncology Letters 12:4, pages 2702-2709.
Crossref
Yixiao Shen, Liqing Du, Haiying Zeng, Xiumei Zhang, Witoon Prinyawiwatkul, Jose R. Alonso-Marenco & Zhimin Xu. (2016) Butterfly pea ( Clitoria ternatea ) seed and petal extracts decreased HEp-2 carcinoma cell viability . International Journal of Food Science & Technology 51:8, pages 1860-1868.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.