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The Journal of Maternal-Fetal & Neonatal Medicine Volume 26, 2013 - Issue 2
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The fetal fraction of cell-free DNA in maternal plasma is not affected by a priori risk of fetal trisomy

Herb BrarRiverside Perinatal Diagnostic Center, Riverside, CA, USA
,
Eric WangAriosa Diagnostics, San Jose, CA, USA
,
Craig StrubleAriosa Diagnostics, San Jose, CA, USA
,
Thomas J. MusciAriosa Diagnostics, San Jose, CA, USACorrespondence[email protected]
&
Mary E. NortonStanford University/Lucile Packard Children’s Hospital, Obstetrics & Gynecology, Stanford, CA, USA
Pages 143-145 | Received 23 Jul 2012, Accepted 16 Aug 2012, Published online: 12 Sep 2012

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Stella Capriglione, Silvia Latella, Giovanna De Felice, Maurizio Filippini, Carla Ettore, Giuseppe Ettore, Miriam Farinelli & Ferdinando Antonio Gulino. (2022) First trimester screening for aneuploidy: may combined test and fetal DNA work together?. The Journal of Maternal-Fetal & Neonatal Medicine 35:22, pages 4258-4262.
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Huso Yi, Olivia Miu Yung Ngan, Sian Griffiths & Daljit Sahota. (2015) Ethical Concerns in the Implementation of DNA Sequencing-Based Noninvasive Prenatal Testing for Fetal Aneuploidy Among Obstetric Professionals in Hong Kong. AJOB Empirical Bioethics 6:1, pages 81-93.
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Cechuan Deng & Shanling Liu. (2022) Factors Affecting the Fetal Fraction in Noninvasive Prenatal Screening: A Review. Frontiers in Pediatrics 10.
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Glenn E. Palomaki & Robert G. Best. 2019. Genomic Applications in Pathology. Genomic Applications in Pathology 561 582 .
T Wataganara, T-H Bui, KW Choy & TY Leung. (2016) Debates on fetal fraction measurement and DNA-based noninvasive prenatal screening: time for standardisation?. BJOG: An International Journal of Obstetrics & Gynaecology 123, pages 31-35.
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Jodi S. Dashe. (2016) Aneuploidy Screening in Pregnancy. Obstetrics & Gynecology 128:1, pages 181-194.
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Nobuhiro Suzumori, Takeshi Ebara, Takahiro Yamada, Osamu Samura, Junko Yotsumoto, Miyuki Nishiyama, Kiyonori Miura, Hideaki Sawai, Jun Murotsuki, Michihiro Kitagawa, Yoshimasa Kamei, Hideaki Masuzaki, Fumiki Hirahara, Juan-Sebastian Saldivar, Nilesh Dharajiya, Haruhiko Sago & Akihiko Sekizawa. (2016) Fetal cell-free DNA fraction in maternal plasma is affected by fetal trisomy. Journal of Human Genetics 61:7, pages 647-652.
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Britton D. Rink & Mary E. Norton. (2016) Screening for fetal aneuploidy. Seminars in Perinatology 40:1, pages 35-43.
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Kristen M. Rauch, Melissa A. Hicks, Henry Adekola & Jacques S. Abramowicz. 2016. First-Trimester Ultrasound. First-Trimester Ultrasound 131 152 .
Sebastian Larion, Steven L. Warsof, Letty Romary, Margaret Mlynarczyk, David Peleg & Alfred Z. Abuhamad. (2015) Use of the Combined First‐Trimester Screen in High‐ and Low‐Risk Patient Populations After Introduction of Noninvasive Prenatal Testing. Journal of Ultrasound in Medicine 34:8, pages 1423-1428.
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Sarah L. Kinnings, Jennifer A. Geis, Eyad Almasri, Huiquan Wang, Xiaojun Guan, Ron M. McCullough, Allan T. Bombard, Juan-Sebastian Saldivar, Paul Oeth & Cosmin Deciu. (2015) Factors affecting levels of circulating cell-free fetal DNA in maternal plasma and their implications for noninvasive prenatal testing. Prenatal Diagnosis 35:8, pages 816-822.
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H. Zhang, Y. Gao, F. Jiang, M. Fu, Y. Yuan, Y. Guo, Z. Zhu, M. Lin, Q. Liu, Z. Tian, H. Zhang, F. Chen, T. K. Lau, L. Zhao, X. Yi, Y. Yin & W. Wang. (2015) Non-invasive prenatal testing for trisomies 21, 18 and 13: clinical experience from 146 958 pregnancies. Ultrasound in Obstetrics & Gynecology 45:5, pages 530-538.
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Glenn E. Palomaki. 2015. Genomic Applications in Pathology. Genomic Applications in Pathology 563 580 .
Anthony R. GreggIgnatia B. Van den VeyverSusan J. GrossRajeevi MadankumarBritton D. RinkMary E. Norton. (2014) Noninvasive Prenatal Screening by Next-Generation Sequencing. Annual Review of Genomics and Human Genetics 15:1, pages 327-347.
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Peter Benn. (2014) Non-Invasive Prenatal Testing Using Cell Free DNA in Maternal Plasma: Recent Developments and Future Prospects. Journal of Clinical Medicine 3:2, pages 537-565.
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Irena Hudecova, Daljit Sahota, Macy M. S. Heung, Yongjie Jin, Wing S. Lee, Tak Y. Leung, Yuk Ming Dennis Lo & Rossa W.K. Chiu. (2014) Maternal Plasma Fetal DNA Fractions in Pregnancies with Low and High Risks for Fetal Chromosomal Aneuploidies. PLoS ONE 9:2, pages e88484.
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Diana W. Bianchi, Dick Oepkes & Alessandro Ghidini. (2014) Current controversies in prenatal diagnosis 1: should noninvasive DNA testing be the standard screening test for Down syndrome in all pregnant women?. Prenatal Diagnosis 34:1, pages 6-11.
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P. Benn, H. Cuckle & E. Pergament. (2013) Non-invasive prenatal testing for aneuploidy: current status and future prospects. Ultrasound in Obstetrics & Gynecology 42:1, pages 15-33.
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Peter Benn, Antoni Borell, Rossa Chiu, Howard Cuckle, Lorraine Dugoff, Brigitte Faas, Susan Gross, Joann Johnson, Ron Maymon, Mary Norton, Anthony Odibo, Peter Schielen, Kevin Spencer, Tianhua Huang, Dave Wright & Yuval Yaron. (2013) Position statement from the Aneuploidy Screening Committee on behalf of the Board of the International Society for Prenatal Diagnosis. Prenatal Diagnosis 33:7, pages 622-629.
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Eric Wang, Annette Batey, Craig Struble, Thomas Musci, Ken Song & Arnold Oliphant. (2013) Gestational age and maternal weight effects on fetal cell-free DNA in maternal plasma. Prenatal Diagnosis 33:7, pages 662-666.
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Genevieve Fairbrother, Shayla Johnson, Thomas J. Musci & Ken Song. (2013) Clinical experience of noninvasive prenatal testing with cell-free DNA for fetal trisomies 21, 18, and 13, in a general screening population. Prenatal Diagnosis 33:6, pages 580-583.
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. (2013) ACOG approves new trisomy screen for high‐risk pregnancies. American Journal of Medical Genetics Part A 161:3.
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