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Research Article

Single dose recombinant erythropoietin versus moderate hypothermia for neonatal hypoxic ischemic encephalopathy in low resource settings

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Pages 1295-1300 | Received 05 Jul 2013, Accepted 12 Oct 2013, Published online: 13 Nov 2013

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Bhawandeep Garg, Deepak Sharma & Anju Bansal. (2018) Systematic review seeking erythropoietin role for neuroprotection in neonates with hypoxic ischemic encephalopathy: presently where do we stand. The Journal of Maternal-Fetal & Neonatal Medicine 31:23, pages 3214-3224.
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Gillian C Pet & Sandra E Juul. (2014) The potential of erythropoietin to treat asphyxia in newborns. Research and Reports in Neonatology 4, pages 195-207.
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Articles from other publishers (30)

Jing-Jing Pan, Yue Wu, Yun Liu, Rui Cheng, Xiao-Qing Chen & Yang Yang. (2023) The effect of erythropoietin on neonatal hypoxic-ischemic encephalopathy: An updated meta-analysis of randomized control trials. Frontiers in Pediatrics 10.
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Ioannis Bellos & Aakash Pandita. (2023) Response to Letter “Therapeutic Hypothermia for Neonatal Encephalopathy in Low-Resource Settings: Methodological Inaccuracies and Inconsistencies in the Latest Systematic Review”. Neonatology 120:2, pages 270-271.
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Joseph L. Mathew, Navneet Kaur & Jeanne Maria Dsouza. (2023) Therapeutic Hypothermia for Neonatal Encephalopathy in Low-Resource Settings: Methodological Inaccuracies and Inconsistencies in the Latest Systematic Review. Neonatology 120:2, pages 268-269.
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Joanne O Davidson, Malcolm R Battin & Alistair J Gunn. (2023) Implications of the HELIX trial for treating infants with hypoxic-ischaemic encephalopathy in low-to-middle-income countries. Archives of Disease in Childhood - Fetal and Neonatal Edition 108:1, pages 83-84.
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Antti Juhani Kukka, Sara Waheddoost, Nick Brown, Helena Litorp, Johan Wrammert & Ashish KC. (2022) Incidence and outcomes of intrapartum-related neonatal encephalopathy in low-income and middle-income countries: a systematic review and meta-analysis. BMJ Global Health 7:12, pages e010294.
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Karina A. Pedroza-García, Denisse Calderón-Vallejo & J. Luis Quintanar. (2022) Neonatal Hypoxic–Ischemic Encephalopathy: Perspectives of Neuroprotective and Neuroregenerative Treatments. Neuropediatrics 53:06, pages 402-417.
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Joseph L Mathew, Navneet Kaur & Jeanne M Dsouza. (2022) Therapeutic hypothermia in neonatal hypoxic encephalopathy: A systematic review and meta-analysis. Journal of Global Health 12.
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Serafina Perrone, Chiara Lembo, Federica Gironi, Chiara Petrolini, Tiziana Catalucci, Giulia Corbo, Giuseppe Buonocore, Eloisa Gitto & Susanna Maria Roberta Esposito. (2022) Erythropoietin as a Neuroprotective Drug for Newborn Infants: Ten Years after the First Use. Antioxidants 11:4, pages 652.
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Suresh Victor, Eridan Rocha-Ferreira, Ahad Rahim, Henrik Hagberg & David Edwards. (2021) New possibilities for neuroprotection in neonatal hypoxic-ischemic encephalopathy. European Journal of Pediatrics 181:3, pages 875-887.
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Silvia Martini, Laura Castellini, Roberta Parladori, Vittoria Paoletti, Arianna Aceti & Luigi Corvaglia. (2021) Free Radicals and Neonatal Brain Injury: From Underlying Pathophysiology to Antioxidant Treatment Perspectives. Antioxidants 10:12, pages 2012.
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Phoebe Ivain, Paolo Montaldo, Aamir Khan, Ramyia Elagovan, Constance Burgod, Maria Moreno Morales, Stuti Pant & Sudhin Thayyil. (2021) Erythropoietin monotherapy for neuroprotection after neonatal encephalopathy in low-to-middle income countries: a systematic review and meta-analysis. Journal of Perinatology 41:9, pages 2134-2140.
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Vaisakh Krishnan, Vijay Kumar, Seetha Shankaran & Sudhin Thayyil. (2021) Rise and Fall of Therapeutic Hypothermia in Low-Resource Settings: Lessons from the HELIX Trial. Indian Journal of Pediatrics.
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Guido Wassink, Joanne O Davidson, Alyssa Crisostomo, Kelly Q Zhou, Robert Galinsky, Simerdeep K Dhillon, Christopher A Lear, Laura Bennet & Alistair J Gunn. (2021) Recombinant erythropoietin does not augment hypothermic white matter protection after global cerebral ischaemia in near-term fetal sheep. Brain Communications 3:3.
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Ryan M. McAdams & Megan W. Berube. (2021) Emerging therapies and management for neonatal encephalopathy—controversies and current approaches. Journal of Perinatology 41:4, pages 661-674.
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Zi-Bin Zhang, Liu-Lin Xiong, Lu-Lu Xue, Yan-Ping Deng, Ruo-Lan Du, Qiao Hu, Yang Xu, Si-Jin Yang & Ting-Hua Wang. (2021) MiR-127-3p targeting CISD1 regulates autophagy in hypoxic–ischemic cortex. Cell Death & Disease 12:3.
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Rukhmani Narayanamurthy, Jung-Lynn Jonathan Yang, Jerome Y. Yager & Larry D. Unsworth. (2021) Drug delivery platforms for neonatal brain injury. Journal of Controlled Release 330, pages 765-787.
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Myra H. Wyckoff & Chair; Gary M. Weiner. (2021) 2020 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. Pediatrics 147:Supplement 1.
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Myra H. Wyckoff, Jonathan Wyllie, Khalid Aziz, Maria Fernanda de Almeida, Jorge W. Fabres, Joe Fawke, Ruth Guinsburg, Shigeharu Hosono, Tetsuya Isayama, Vishal S. Kapadia, Han-Suk Kim, Helen G. Liley, Christopher J.D. McKinlay, Lindsay Mildenhall, Jeffrey M. Perlman, Yacov Rabi, Charles C. Roehr, Georg M. Schmölzer, Edgardo Szyld, Daniele Trevisanuto, Sithembiso Velaphi, Gary M. Weiner, Peter G. Davis, Jennifer Dawson, Hege Ersdal, Elizabeth E. Foglia, Mandira Kawakami, Henry C. Lee, Mario Rüdiger, Taylor Sawyer, Amouchou Soraisham, Marya Strand, Enrique Udaeta, Berndt Urlesburger, Nicole K. Yamada, John Madar, Marilyn B. Escobedo, Abhrajit Ganguly, Callum Gately, Beena Kamath-Rayne, Richard Mausling, Jocelyn Domingo-Bates, Firdose Nakwa, Shalini Ramachandran, Jenny Ring, Birju Shah, Christopher Stave, Masanori Tamura & Arjan te Pas. (2020) Neonatal Life Support 2020 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. Resuscitation 156, pages A156-A187.
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Myra H. Wyckoff, Jonathan Wyllie, Khalid Aziz, Maria Fernanda de Almeida, Jorge Fabres, Joe Fawke, Ruth Guinsburg, Shigeharu Hosono, Tetsuya Isayama, Vishal S. Kapadia, Han-Suk Kim, Helen G. Liley, Christopher J.D. McKinlay, Lindsay Mildenhall, Jeffrey M. Perlman, Yacov Rabi, Charles C. Roehr, Georg M. Schmölzer, Edgardo Szyld, Daniele Trevisanuto, Sithembiso Velaphi, Gary M. Weiner, Peter G. Davis, Jennifer Dawson, Hege Ersdal, Elizabeth E. Foglia, Mandira Kawakami, Henry C. Lee, Mario Rüdiger, Taylor Sawyer, Amuchou Soraisham, Marya Strand, Enrique Udaeta, Berndt Urlesberger, Nicole K. Yamada, John Madar, Marilyn B. Escobedo, Abhrajit Ganguly, Callum Gately, Beena Kamath-Rayne, Richard Mausling, Jocelyn Domingo-Bates, Firdose Nakwa, Shalini Ramachandran, Jenny Ring, Birju Shah, Christopher Stave, Masanori Tamura, Arjan te Pas, Catherine Cheng, Walid El-Naggar, Emer Finan, Janene Fuerch, Lou Halamek, Omar Kamlin, Satyan Lakshminrusimha, Jane McGowan, Susan Niermeyer, Bin Huey Quek, Nalini Singhal & Daniela Testoni. (2020) Neonatal Life Support: 2020 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. Circulation 142:16_suppl_1.
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Simerdeep K. Dhillon, Guido Wassink, Christopher A. Lear, Joanne O. Davidson, Nicholas H.G. Holford, Alistair J. Gunn & Laura Bennet. (2020) The Effect of Size, Maturation, Global Asphyxia, Cerebral Ischemia, and Therapeutic Hypothermia on the Pharmacokinetics of High-Dose Recombinant Erythropoietin in Fetal Sheep. International Journal of Molecular Sciences 21:9, pages 3042.
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Silvia Martini, Topun Austin, Arianna Aceti, Giacomo Faldella & Luigi Corvaglia. (2019) Free radicals and neonatal encephalopathy: mechanisms of injury, biomarkers, and antioxidant treatment perspectives. Pediatric Research 87:5, pages 823-833.
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Guido Wassink, Joanne O. Davidson, Mhoyra Fraser, Caroline A. Yuill, Laura Bennet & Alistair J. Gunn. (2020) Non‐additive effects of adjunct erythropoietin therapy with therapeutic hypothermia after global cerebral ischaemia in near‐term fetal sheep. The Journal of Physiology 598:5, pages 999-1015.
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Dorothy E. Oorschot, Rachel J. Sizemore & Ashraf R. Amer. (2020) Treatment of Neonatal Hypoxic-Ischemic Encephalopathy with Erythropoietin Alone, and Erythropoietin Combined with Hypothermia: History, Current Status, and Future Research. International Journal of Molecular Sciences 21:4, pages 1487.
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Jessie R. Maxwell & Robin K. Ohls. (2019) Update on Erythropoiesis-Stimulating Agents Administered to Neonates for Neuroprotection. NeoReviews 20:11, pages e622-e635.
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Ted S. Rosenkrantz, Zeenat Hussain & Roslyn Holly Fitch. (2019) Sex Differences in Brain Injury and Repair in Newborn Infants: Clinical Evidence and Biological Mechanisms. Frontiers in Pediatrics 7.
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Abdul Razak & Asif Hussain. (2019) Erythropoietin in perinatal hypoxic-ischemic encephalopathy: a systematic review and meta-analysis. Journal of Perinatal Medicine 47:4, pages 478-489.
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Ruth Gussenhoven, Rob J. J. Westerlaken, Daan R. M. G. Ophelders, Alan H. Jobe, Matthew W. Kemp, Suhas G. Kallapur, Luc J. Zimmermann, Per T. Sangild, Stanislava Pankratova, Pierre Gressens, Boris W. Kramer, Bobbi Fleiss & Tim G. A. M. Wolfs. (2018) Chorioamnionitis, neuroinflammation, and injury: timing is key in the preterm ovine fetus. Journal of Neuroinflammation 15:1.
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R R Malla, R Asimi, M A Teli, F Shaheen & M A Bhat. (2017) Erythropoietin monotherapy in perinatal asphyxia with moderate to severe encephalopathy: a randomized placebo-controlled trial. Journal of Perinatology 37:5, pages 596-601.
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Sahar M. A. HassaneinMohamed Hassan Nasr EldinHanaa A. AmerAdel E. AbdelhamidMoustafa El HoussinieAbir Ibrahim. (2017) Human Umbilical Cord Blood CD34-Positive Cells as Predictors of the Incidence and Short-Term Outcome of Neonatal Hypoxic-Ischemic Encephalopathy: A Pilot Study. Journal of Clinical Neurology 13:1, pages 84.
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Sahar M.A. HassaneinShaymaa M. DeifallaMoustafa El-HoussinieSomaia A. Mokbel. (2016) Safety and Efficacy of Cerebrolysin in Infants with Communication Defects due to Severe Perinatal Brain Insult: A Randomized Controlled Clinical Trial. Journal of Clinical Neurology 12:1, pages 79.
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