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Capsaicin 8% Topical Patch (Qutenza)—A Review of the Evidence

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Pages 32-41 | Published online: 24 Mar 2011

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Sudhir M Baswan, Allison E Klosner, Kelly Glynn, Arun Rajgopal, Kausar Malik, Sunghan Yim & Nathan Stern. (2020) Therapeutic Potential of Cannabidiol (CBD) for Skin Health and Disorders. Clinical, Cosmetic and Investigational Dermatology 13, pages 927-942.
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R.-D. Treede, T. Wagner, K.-U. Kern, I.W. Husstedt, G. Arendt, F. Birklein, T. Cegla, R. Freynhagen, H.-H. Gockel, M.-L. Heskamp, H. Jager, R. Joppich, C. Maier, A. Leffler, H.-H. Nagelein, R. Rolke, S. Seddigh, C. Sommer, S. Stander, G. Wasner & R. Baron. (2013) Mechanism- and experience-based strategies to optimize treatment response to the capsaicin 8% cutaneous patch in patients with localized neuropathic pain. Current Medical Research and Opinion 29:5, pages 527-538.
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Alain Borgeat (Switzerland) with commentaries from Ganaan Banaridharan (United Kingdom) and Mats Karlsson (Sweden). (2012) Topical Capsaicin in Severe Neuropathic Pain. Journal of Pain & Palliative Care Pharmacotherapy 26:2, pages 190-192.
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Naum Shaparin, Singh Nair, Amaresh Vydyanathan & Jacob R. Hascalovici. (2021) Expanding frontiers in telehealth: Video assisted at‐home application of capsaicin 8% patch. European Journal of Pain 25:7, pages 1564-1567.
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Mary A. Robinson, Darko Stefanovski, Youwen You, Raymond C. Boston & Lawrence R. Soma. (2020) Bayesian‐based withdrawal estimates using pharmacokinetic parameters for two capsaicinoid‐containing products administered to horses. Journal of Veterinary Pharmacology and Therapeutics 44:3, pages 349-358.
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Huilong Luo, Xavier Declèves & Salvatore Cisternino. (2021) Transient Receptor Potential Vanilloid in the Brain Gliovascular Unit: Prospective Targets in Therapy. Pharmaceutics 13:3, pages 334.
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Petros G. Botonis, Panagiotis G. Miliotis, Stylianos N. Kounalakis, Maria D. Koskolou & Nickos D. Geladas. (2019) Effects of capsaicin application on the skin during resting exposure to temperate and warm conditions. Scandinavian Journal of Medicine & Science in Sports 29:2, pages 171-179.
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Sunil Panchal, Edward Bliss & Lindsay Brown. (2018) Capsaicin in Metabolic Syndrome. Nutrients 10:5, pages 630.
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Magdalene M. Moran. (2018) TRP Channels as Potential Drug Targets. Annual Review of Pharmacology and Toxicology 58:1, pages 309-330.
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Paul D Gavin, Lee S Simon, Thomas Schlagheck, Alisha J Smith & Janakan Krishnarajah. (2017) A Phase I study of the pharmacokinetics, safety and tolerability of a novel tocopheryl phosphate mixture/oxymorphone transdermal patch system. Pain Management 7:6, pages 499-512.
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H.H. Andersen, J.B. Marker, E.A. Hoeck, J. Elberling & L. Arendt-Nielsen. (2017) Antipruritic effect of pretreatment with topical capsaicin 8% on histamine- and cowhage-evoked itch in healthy volunteers: a randomized, vehicle-controlled, proof-of-concept trial. British Journal of Dermatology 177:1, pages 107-116.
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Vananélia P.N. Geraldo, Analine C. Ziglio, Débora Gonçalves & Osvaldo N. OliveiraJr.Jr.. (2017) Interaction of capsaicinoids with cell membrane models does not correlate with pungency of peppers. Chemical Physics Letters 673, pages 78-83.
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Nicholas Hylands-White, Rui V. Duarte & Jon H. Raphael. (2016) An overview of treatment approaches for chronic pain management. Rheumatology International 37:1, pages 29-42.
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Ning-Ning Wei, Hai-Ning Lv, Yang Wu, Shi-Long Yang, Xiao-Ying Sun, Ren Lai, Yong Jiang & KeWei Wang. (2016) Selective Activation of Nociceptor TRPV1 Channel and Reversal of Inflammatory Pain in Mice by a Novel Coumarin Derivative Muralatin L from Murraya alata. Journal of Biological Chemistry 291:2, pages 640-651.
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