A Randomized, Placebo Controlled Trial of Oral Zinc for Chemotherapy-Related Taste and Smell Disorders

Laurel LyckholmLaurel Lyckholm, MD, is Professor of Hematology/Oncology and Palliative Care, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA; Steven P. Heddinger, MD, is a member of Medical Oncology and Hematology Associates, Cancer Center of Iowa, Des Moines, Iowa, USA; Gwendolyn Parker, MS, FNP-C, is a clinician and research nurse at Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA; Patrick J. Coyne, MSN, APRN, FAAN, is Clinical Director, Pain and Palliative Care, Thomas Palliative Care Services, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA; Viswanathan Ramakrishnan, PhD, is Professor, Division of Biostatistics and Epidemiology, Medical University of South Carolina, Charleston, South Carolina, USA; Thomas J. Smith, MD, is Professor and Director of Palliative Medicine, Johns Hopkins Medical Institutions, Johns Hopkins University, Baltimore, Maryland, USA; and Robert I. Henkin, MD, PhD, is Director of the Center for Molecular Nutrition and Sensory Disorders, and Clinical Director of The Taste and Smell Clinic, Washington, DC, USA.Correspondence[email protected]

Steven P. HeddingerLaurel Lyckholm, MD, is Professor of Hematology/Oncology and Palliative Care, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA; Steven P. Heddinger, MD, is a member of Medical Oncology and Hematology Associates, Cancer Center of Iowa, Des Moines, Iowa, USA; Gwendolyn Parker, MS, FNP-C, is a clinician and research nurse at Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA; Patrick J. Coyne, MSN, APRN, FAAN, is Clinical Director, Pain and Palliative Care, Thomas Palliative Care Services, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA; Viswanathan Ramakrishnan, PhD, is Professor, Division of Biostatistics and Epidemiology, Medical University of South Carolina, Charleston, South Carolina, USA; Thomas J. Smith, MD, is Professor and Director of Palliative Medicine, Johns Hopkins Medical Institutions, Johns Hopkins University, Baltimore, Maryland, USA; and Robert I. Henkin, MD, PhD, is Director of the Center for Molecular Nutrition and Sensory Disorders, and Clinical Director of The Taste and Smell Clinic, Washington, DC, USA.

Gwendolyn ParkerLaurel Lyckholm, MD, is Professor of Hematology/Oncology and Palliative Care, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA; Steven P. Heddinger, MD, is a member of Medical Oncology and Hematology Associates, Cancer Center of Iowa, Des Moines, Iowa, USA; Gwendolyn Parker, MS, FNP-C, is a clinician and research nurse at Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA; Patrick J. Coyne, MSN, APRN, FAAN, is Clinical Director, Pain and Palliative Care, Thomas Palliative Care Services, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA; Viswanathan Ramakrishnan, PhD, is Professor, Division of Biostatistics and Epidemiology, Medical University of South Carolina, Charleston, South Carolina, USA; Thomas J. Smith, MD, is Professor and Director of Palliative Medicine, Johns Hopkins Medical Institutions, Johns Hopkins University, Baltimore, Maryland, USA; and Robert I. Henkin, MD, PhD, is Director of the Center for Molecular Nutrition and Sensory Disorders, and Clinical Director of The Taste and Smell Clinic, Washington, DC, USA.

Patrick J. CoyneLaurel Lyckholm, MD, is Professor of Hematology/Oncology and Palliative Care, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA; Steven P. Heddinger, MD, is a member of Medical Oncology and Hematology Associates, Cancer Center of Iowa, Des Moines, Iowa, USA; Gwendolyn Parker, MS, FNP-C, is a clinician and research nurse at Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA; Patrick J. Coyne, MSN, APRN, FAAN, is Clinical Director, Pain and Palliative Care, Thomas Palliative Care Services, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA; Viswanathan Ramakrishnan, PhD, is Professor, Division of Biostatistics and Epidemiology, Medical University of South Carolina, Charleston, South Carolina, USA; Thomas J. Smith, MD, is Professor and Director of Palliative Medicine, Johns Hopkins Medical Institutions, Johns Hopkins University, Baltimore, Maryland, USA; and Robert I. Henkin, MD, PhD, is Director of the Center for Molecular Nutrition and Sensory Disorders, and Clinical Director of The Taste and Smell Clinic, Washington, DC, USA.

Viswanathan RamakrishnanLaurel Lyckholm, MD, is Professor of Hematology/Oncology and Palliative Care, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA; Steven P. Heddinger, MD, is a member of Medical Oncology and Hematology Associates, Cancer Center of Iowa, Des Moines, Iowa, USA; Gwendolyn Parker, MS, FNP-C, is a clinician and research nurse at Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA; Patrick J. Coyne, MSN, APRN, FAAN, is Clinical Director, Pain and Palliative Care, Thomas Palliative Care Services, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA; Viswanathan Ramakrishnan, PhD, is Professor, Division of Biostatistics and Epidemiology, Medical University of South Carolina, Charleston, South Carolina, USA; Thomas J. Smith, MD, is Professor and Director of Palliative Medicine, Johns Hopkins Medical Institutions, Johns Hopkins University, Baltimore, Maryland, USA; and Robert I. Henkin, MD, PhD, is Director of the Center for Molecular Nutrition and Sensory Disorders, and Clinical Director of The Taste and Smell Clinic, Washington, DC, USA.

Thomas J. SmithLaurel Lyckholm, MD, is Professor of Hematology/Oncology and Palliative Care, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA; Steven P. Heddinger, MD, is a member of Medical Oncology and Hematology Associates, Cancer Center of Iowa, Des Moines, Iowa, USA; Gwendolyn Parker, MS, FNP-C, is a clinician and research nurse at Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA; Patrick J. Coyne, MSN, APRN, FAAN, is Clinical Director, Pain and Palliative Care, Thomas Palliative Care Services, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA; Viswanathan Ramakrishnan, PhD, is Professor, Division of Biostatistics and Epidemiology, Medical University of South Carolina, Charleston, South Carolina, USA; Thomas J. Smith, MD, is Professor and Director of Palliative Medicine, Johns Hopkins Medical Institutions, Johns Hopkins University, Baltimore, Maryland, USA; and Robert I. Henkin, MD, PhD, is Director of the Center for Molecular Nutrition and Sensory Disorders, and Clinical Director of The Taste and Smell Clinic, Washington, DC, USA.

Robert I. HenkinLaurel Lyckholm, MD, is Professor of Hematology/Oncology and Palliative Care, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA; Steven P. Heddinger, MD, is a member of Medical Oncology and Hematology Associates, Cancer Center of Iowa, Des Moines, Iowa, USA; Gwendolyn Parker, MS, FNP-C, is a clinician and research nurse at Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA; Patrick J. Coyne, MSN, APRN, FAAN, is Clinical Director, Pain and Palliative Care, Thomas Palliative Care Services, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA; Viswanathan Ramakrishnan, PhD, is Professor, Division of Biostatistics and Epidemiology, Medical University of South Carolina, Charleston, South Carolina, USA; Thomas J. Smith, MD, is Professor and Director of Palliative Medicine, Johns Hopkins Medical Institutions, Johns Hopkins University, Baltimore, Maryland, USA; and Robert I. Henkin, MD, PhD, is Director of the Center for Molecular Nutrition and Sensory Disorders, and Clinical Director of The Taste and Smell Clinic, Washington, DC, USA.

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A Randomized, Placebo Controlled Trial of Oral Zinc for Chemotherapy-Related Taste and Smell Disorders

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A Randomized, Placebo Controlled Trial of Oral Zinc for Chemotherapy-Related Taste and Smell Disorders

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