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Research Article

The influence of combinations of oximes on the reactivating and therapeutic efficacy of antidotal treatment of soman poisoning in rats and mice

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Pages 547-551 | Received 07 Aug 2009, Accepted 20 Sep 2009, Published online: 19 Oct 2009

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Jiri Bajgar, Petr Hajek, Jiri Kassa, Dasa Slizova, Otakar Krs, Jana Zdarova Karasova, Josef Fusek, Lukas Capek & Victor A. Voicu. (2012) Combined approach to demonstrate acetylcholinesterase activity changes in the rat brain following tabun intoxication and its treatment. Toxicology Mechanisms and Methods 22:1, pages 60-66.
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Articles from other publishers (7)

Lukas Gorecki, Ondrej Soukup, Tomas Kucera, David Malinak, Daniel Jun, Kamil Kuca, Kamil Musilek & Jan Korabecny. (2018) Oxime K203: a drug candidate for the treatment of tabun intoxication. Archives of Toxicology 93:3, pages 673-691.
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Evica Antonijevic, Kamil Musilek, Kamil Kuca, Danijela Djukic-Cosic, Slavica Vucinic & Biljana Antonijevic. (2016) Therapeutic and reactivating efficacy of oximes K027 and K203 against a direct acetylcholinesterase inhibitor. NeuroToxicology 55, pages 33-39.
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Jiří Kassa, Jana Zdarová Karasová, Růžena Pavlíková, Filip Caisberger & Jiří Bajgar. (2012) The Ability of Oxime Mixtures to Increase the Reactivating and Therapeutic Efficacy of Antidotal Treatment of Cyclosarin Poisoning in Rats and Mice. Acta Medica (Hradec Kralove, Czech Republic) 55:1, pages 27-31.
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Jiri Kassa, Jana Zdarova Karasova, Vendula Sepsova, Filip Caisberger & Jiri Bajgar. (2011) A Comparison of the Reactivating and Therapeutic Efficacy of Chosen Combinations of Oximes With Individual Oximes Against VX in Rats and Mice. International Journal of Toxicology 30:5, pages 562-567.
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Jiri Kassa, Jana Zdarova Karasova, Vendula Sepsova & Filip Caisberger. (2011) The Benefit of Combinations of Oximes for the Reactivating and Therapeutic Efficacy of Antidotal Treatment of Sarin Poisoning in Rats and Mice. Basic & Clinical Pharmacology & Toxicology 109:1, pages 30-34.
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Jiří Kassa & Jana Žďárová Karasová. (2011) A COMPARISON OF THE NEUROPROTECTIVE EFFICACY OF INDIVIDUAL OXIMES (HI-6, TRIMEDOXIME, K203) AND THEIR MIXTURES (HI-6 + TRIMEDOXIME, HI-6 + K203) IN CYCLOSARIN-POISONED RATS. Military Medical Science Letters 80:1, pages 12-20.
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Rinkoo D Gupta, Moshe Goldsmith, Yacov Ashani, Yair Simo, Gavriel Mullokandov, Hagit Bar, Moshe Ben-David, Haim Leader, Raanan Margalit, Israel Silman, Joel L Sussman & Dan S Tawfik. (2011) Directed evolution of hydrolases for prevention of G-type nerve agent intoxication. Nature Chemical Biology 7:2, pages 120-125.
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