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Research Article

Honokiol induces paraptosis and apoptosis and exhibits schedule-dependent synergy in combination with imatinib in human leukemia cells

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Pages 234-241 | Received 22 Jan 2010, Accepted 03 Mar 2010, Published online: 07 Apr 2010

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Xiao-Qin Li, Jing Ren, Yi Wang, Jin-Yu Su, Yu-Min Zhu, Chen-Guo Chen, Wei-Guo Long, Qian Jiang & Jian Li. (2020) Synergistic killing effect of paclitaxel and honokiol in non-small cell lung cancer cells through paraptosis induction. Cellular Oncology 44:1, pages 135-150.
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Fabrizio Fontana, Michela Raimondi, Monica Marzagalli, Alessandro Di Domizio & Patrizia Limonta. (2020) The emerging role of paraptosis in tumor cell biology: Perspectives for cancer prevention and therapy with natural compounds. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1873:2, pages 188338.
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Seon Min Woo, Seung Un Seo, Peter Kubatka, Kyoung-jin Min & Taeg Kyu Kwon. (2019) Honokiol Enhances TRAIL-Mediated Apoptosis through STAMBPL1-Induced Survivin and c-FLIP Degradation. Biomolecules 9:12, pages 838.
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Yujia Wang, Xiang Wen, Nan Zhang, Lian Wang, Dan Hao, Xian Jiang & Gu He. (2019) Small-molecule compounds target paraptosis to improve cancer therapy. Biomedicine & Pharmacotherapy 118, pages 109203.
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Kishore Banik, Abhishek Manoj Ranaware, Vishwas Deshpande, Savita Pravin Nalawade, Ganesan Padmavathi, Devivasha Bordoloi, Bethsebie Lalduhsaki Sailo, Muthu K. Shanmugam, Lu Fan, Frank Arfuso, Gautam Sethi & Ajaikumar B. Kunnumakkara. (2019) Honokiol for cancer therapeutics: A traditional medicine that can modulate multiple oncogenic targets. Pharmacological Research 144, pages 192-209.
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Abdur Rauf, Seema Patel, Muhammad Imran, Aneela Maalik, Muhammad Umair Arshad, Farhan Saeed, Yahia N. Mabkhot, Salim S. Al-Showiman, Nazir Ahmad & Eman Elsharkawy. (2018) Honokiol: An anticancer lignan. Biomedicine & Pharmacotherapy 107, pages 555-562.
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Maryam Khalili & James A. Radosevich. 2018. Apoptosis and Beyond. Apoptosis and Beyond 343 366 .
Kao-Jean Huang, Chin-Ho Kuo, Shu-Hsin Chen, Ching-Yen Lin & Ying-Ray Lee. (2018) Honokiol inhibits in vitro and in vivo growth of oral squamous cell carcinoma through induction of apoptosis, cell cycle arrest and autophagy . Journal of Cellular and Molecular Medicine 22:3, pages 1894-1908.
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Bin Zhou, Haiying Li, Chongyun Xing, Haige Ye, Jianhua Feng, Jianbo Wu, Zhongqiu Lu, Jing Fang & Shenmeng Gao. (2017) Honokiol induces proteasomal degradation of AML1-ETO oncoprotein via increasing ubiquitin conjugase UbcH8 expression in leukemia. Biochemical Pharmacology 128, pages 12-25.
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Marc Diederich & Claudia Cerella. (2016) Non-canonical programmed cell death mechanisms triggered by natural compounds. Seminars in Cancer Biology 40-41, pages 4-34.
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Esma Yagdi, Claudia Cerella, Mario Dicato & Marc Diederich. (2016) Garlic-derived natural polysulfanes as hydrogen sulfide donors: Friend or foe?. Food and Chemical Toxicology 95, pages 219-233.
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Andrey V. Shubin, Ilya V. Demidyuk, Alexey A. Komissarov, Lola M. Rafieva & Sergey V. Kostrov. (2016) Cytoplasmic vacuolization in cell death and survival. Oncotarget 7:34, pages 55863-55889.
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Ryoiti Kiyama. (2016) Biological effects induced by estrogenic activity of lignans. Trends in Food Science & Technology 54, pages 186-196.
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Dongjoo Lee, In Young Kim, Sharmistha Saha & Kyeong Sook Choi. (2016) Paraptosis in the anti-cancer arsenal of natural products. Pharmacology & Therapeutics 162, pages 120-133.
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DONG-PEI JIA, SONG WANG, BAO-CHAO ZHANG & FANG FANG. (2015) Paraptosis triggers mitochondrial pathway-mediated apoptosis in Alzheimer's disease. Experimental and Therapeutic Medicine 10:2, pages 804-808.
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YUBAO ZHANG, XIA REN, MEIYAN SHI, ZHENG JIANG, HENGXIAO WANG, QINGHONG SU, QINGLIN LIU, GANG LI & GUOSHENG JIANG. (2014) Downregulation of STAT3 and activation of MAPK are involved in the induction of apoptosis by HNK in glioblastoma cell line U87. Oncology Reports 32:5, pages 2038-2046.
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Mohamed Saeed, Victor Kuete, Onat Kadioglu, Jonas Börtzler, Hassan Khalid, Henry Johannes Greten & Thomas Efferth. (2014) Cytotoxicity of the bisphenolic honokiol from Magnolia officinalis against multiple drug-resistant tumor cells as determined by pharmacogenomics and molecular docking. Phytomedicine 21:12, pages 1525-1533.
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Yao Wang, Kun Xu, Hongbing Zhang, Junhong Zhao, Xiuping Zhu, Yangzheng Wang & Renyi Wu. (2014) Retinal ganglion cell death is triggered by paraptosis via reactive oxygen species production: A brief literature review presenting a novel hypothesis in glaucoma pathology. Molecular Medicine Reports.
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Mohanad Zbidah, Adrian Lupescu, Tabea Herrmann, Wenting Yang, Michael Foller, Kashif Jilani & Florian Lang. (2013) Effect of honokiol on erythrocytes. Toxicology in Vitro 27:6, pages 1737-1745.
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Alexander Kornienko, Véronique Mathieu, Shiva K. Rastogi, Florence Lefranc & Robert Kiss. (2013) Therapeutic Agents Triggering Nonapoptotic Cancer Cell Death. Journal of Medicinal Chemistry 56:12, pages 4823-4839.
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Hua Sui, Xuan Liu, Bao-Hui Jin, Shu-Fang Pan, Li-Hong Zhou, Nikitin Alexander Yu, Jie Wu, Jian-Feng Cai, Zhong-Ze Fan, Hui-Rong Zhu & Qi Li. (2013) Zuo Jin Wan, a Traditional Chinese Herbal Formula, Reverses P-gp-Mediated MDR In Vitro and In Vivo . Evidence-Based Complementary and Alternative Medicine 2013, pages 1-13.
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Yao Wang, Xiuping Zhu, Zehong Yang & Xiaojun Zhao. (2013) Honokiol induces caspase-independent paraptosis via reactive oxygen species production that is accompanied by apoptosis in leukemia cells. Biochemical and Biophysical Research Communications 430:3, pages 876-882.
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Dong Xu. (2012) Honokiol synergizes chemotherapy drugs in multidrug resistant breast cancer cells via enhanced apoptosis and additional programmed necrotic death. International Journal of Oncology.
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Hemant Kulkarni, Harald H H Göring, Vincent Diego, Shelley Cole, Ken R Walder, Greg R Collier, John Blangero & Melanie A Carless. (2012) Association of differential gene expression with imatinib mesylate and omacetaxine mepesuccinate toxicity in lymphoblastoid cell lines. BMC Medical Genomics 5:1.
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Patrick Steinmann, Denise K. Walters, Matthias J. E. Arlt, Ingo J. Banke, Urs Ziegler, Bettina Langsam, Jack Arbiser, Roman Muff, Walter Born & Bruno Fuchs. (2011) Antimetastatic activity of honokiol in osteosarcoma. Cancer 118:8, pages 2117-2127.
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Yao Xie, Qida Long, QinJie Wu, Shuai Shi, Mei Dai, Yingwei Liu, Lei Liu, Changyang Gong, Zhiyong Qian, Yuquan Wei & Xia Zhao. (2012) Improving therapeutic effect in ovarian peritoneal carcinomatosis with honokiol nanoparticles in a thermosensitive hydrogel composite. RSC Advances 2:20, pages 7759.
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