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Toxicology Mechanisms and Methods Volume 22, 2012 - Issue 3
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Research Article

In silico and in vitro genotoxicity evaluation of levofloxacin n-oxide, an impurity in levofloxacin

Qingfen Zhu
,
Tao LiShandong Institute for Food and Drug Control, Jinan, Shandong, P.R. China
,
Jun LiShandong Institute for Food and Drug Control, Jinan, Shandong, P.R. China
,
Ming GuoShandong Institute for Food and Drug Control, Jinan, Shandong, P.R. China
,
Weijian WangShandong Institute for Food and Drug Control, Jinan, Shandong, P.R. China
&
Xiumei ZhangDepartment of Pharmacology, Shandong University, School of Medicine, Jinan, Shandong, P.R. ChinaCorrespondence[email protected]
Pages 225-230 | Received 23 Jul 2011, Accepted 21 Oct 2011, Published online: 16 Nov 2011

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Valentina Petruševska, Kornelija Lasić & Ana Mornar. (2020) Compatibility investigation for a new antituberculotic fixed dose combination with an adequate drug delivery. Drug Development and Industrial Pharmacy 46:8, pages 1298-1307.
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Esra Emerce, Ismet Cok, Sibel Sari & Omur Bostanci. (2016) An investigation of the mutagenic activity of salamide – a major impurity of hydrochlorothiazide. Toxicology Mechanisms and Methods 26:9, pages 644-649.
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Articles from other publishers (2)

Andrzej Czyrski, Katarzyna Anusiak & Artur Teżyk. (2019) The degradation of levofloxacin in infusions exposed to daylight with an identification of a degradation product with HPLC-MS. Scientific Reports 9:1.
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Esra Emerce, Ismet Cok & I.Tuncer Degim. (2015) Determination of the impurities in drug products containing montelukast and in silico/in vitro genotoxicological assessments of sulfoxide impurity. Toxicology Letters 238:2, pages 90-99.
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