402
Views
35
CrossRef citations to date
0
Altmetric
Research Article

Cardioprotective effects of rosuvastatin and carvedilol on delayed cardiotoxicity of doxorubicin in rats

, , , , , , & show all
Pages 488-498 | Received 08 Jan 2012, Accepted 19 Mar 2012, Published online: 19 Apr 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (1)

Lisa Drange Hole, Terje H. Larsen, Kjell O. Fossan, Fredrik Limé & Jan Schjøtt. (2013) A short-time model to study relevant indices of cardiotoxicity of doxorubicin in the rat. Toxicology Mechanisms and Methods 23:6, pages 412-418.
Read now

Articles from other publishers (34)

Tomas G. Neilan, Thiago Quinaglia, Takeshi Onoue, Syed S. Mahmood, Zsofia D. Drobni, Hannah K. Gilman, Amanda Smith, Julius C. Heemelaar, Priya Brahmbhatt, Jor Sam Ho, Supraja Sama, Jakub Svoboda, Donna S. Neuberg, Jeremy S. Abramson, Ephraim P. Hochberg, Jefferey A. Barnes, Philippe Armand, Eric D. Jacobsen, Caron A. Jacobson, Austin I. Kim, Jacob D. Soumerai, Yuchi Han, Robb S. Friedman, Ann S. Lacasce, Bonnie Ky, Dan Landsburg, Sunita Nasta, Raymond Y. Kwong, Michael Jerosch-Herold, Robert A. Redd, Lanqi Hua, James L. Januzzi, Aarti Asnani, Negareh Mousavi & Marielle Scherrer-Crosbie. (2023) Atorvastatin for Anthracycline-Associated Cardiac Dysfunction. JAMA 330:6, pages 528.
Crossref
Keith Dadson, Paaladinesh Thavendiranathan, Ludger Hauck, Daniela Grothe, Mohammed Ali Azam, Shanna Stanley-Hasnain, Donya Mahiny-Shahmohammady, Daoyuan Si, Mahmoud Bokhari, Patrick F.H. Lai, Stéphane Massé, Kumaraswamy Nanthakumar & Filio Billia. (2022) Statins Protect Against Early Stages of Doxorubicin-induced Cardiotoxicity Through the Regulation of Akt Signaling and SERCA2. CJC Open 4:12, pages 1043-1052.
Crossref
Hayder M. Al-kuraishy, Ali I. Al-Gareeb, Afrah Fahad Alkhuriji, Wafa Abdullah I. Al-Megrin, Engy Elekhnawy, Walaa A. Negm, Michel De Waard & Gaber El-Saber Batiha. (2022) Investigation of the impact of rosuvastatin and telmisartan in doxorubicin-induced acute cardiotoxicity. Biomedicine & Pharmacotherapy 154, pages 113673.
Crossref
Serena L’Abbate, Michela Chianca, Iacopo Fabiani, Annamaria Del Franco, Alberto Giannoni, Giuseppe Vergaro, Chrysanthos Grigoratos, Claudia Kusmic, Claudio Passino, Yuri D’Alessandra, Silvia Burchielli, Michele Emdin & Daniela Maria Cardinale. (2022) In Vivo Murine Models of Cardiotoxicity Due to Anticancer Drugs: Challenges and Opportunities for Clinical Translation. Journal of Cardiovascular Translational Research 15:5, pages 1143-1162.
Crossref
Nonhlakanipho F. Sangweni, Derick van Vuuren, Lawrence Mabasa, Kwazi Gabuza, Barbara Huisamen, Sharnay Naidoo, Reenen Barry & Rabia Johnson. (2022) Prevention of Anthracycline-Induced Cardiotoxicity: The Good and Bad of Current and Alternative Therapies. Frontiers in Cardiovascular Medicine 9.
Crossref
Emily M. Heiston & W. Gregory Hundley. (2022) Statins for Cardiac and Vascular Protection During and After Cancer Therapy. Current Oncology Reports 24:5, pages 555-561.
Crossref
Jacqueline T. Vuong, Ashley F. Stein-Merlob, Richard K. Cheng & Eric H. Yang. (2022) Novel Therapeutics for Anthracycline Induced Cardiotoxicity. Frontiers in Cardiovascular Medicine 9.
Crossref
Sarah A. Baraka, Mai F. Tolba, Doaa A. Elsherbini, Reem N. El‐Naga, Azza S. Awad & Ebtehal El‐Demerdash. (2021) Rosuvastatin and low‐dose carvedilol combination protects against isoprenaline‐induced myocardial infarction in rats: Role of PI3K/Akt/Nrf2/HO‐1 signalling. Clinical and Experimental Pharmacology and Physiology 48:10, pages 1358-1370.
Crossref
Marina Rankovic, Nevena Draginic, Jovana Jeremic, Andjela Milojevic Samanovic, Svetlana Stojkov, Slobodanka Mitrovic, Nevena Jeremic, Tanja Radonjic, Ivan Srejovic, Sergey Bolevich, Andrey Svistunov, Vladimir Jakovljevic & Tamara Nikolic Turnic. (2021) Protective Role of Vitamin B1 in Doxorubicin-Induced Cardiotoxicity in Rats: Focus on Hemodynamic, Redox, and Apoptotic Markers in Heart. Frontiers in Physiology 12.
Crossref
N. V. Tursunova, M. G. Klinnikova, O. A. Babenko & E. L. Lushnikova. (2021) Molecular Mechanisms of the Cardiotoxic Action of Anthracycline Antibiotics and Statin-Induced Cytoprotective Reactions of Cardiomyocytes. Biochemistry (Moscow), Supplement Series B: Biomedical Chemistry 15:2, pages 89-104.
Crossref
Basma S. Mansour, Noha A. Salem, Ghada Abdel Kader, Gamal Abdel-Alrahman & Omayma M. Mahmoud. (2021) Protective effect of Rosuvastatin on Azithromycin induced cardiotoxicity in a rat model. Life Sciences 269, pages 119099.
Crossref
M. G. Klinnikova, E. V. Koldysheva, N. V. Tursunova, D. E. Semenov & E. L. Lushnikova. (2020) Features of Myocardial Remodeling and Changes in the Blood Lipid Spectrum in Experimental Doxorubicin-Induced Cardiomyopathy and Atorvastatin Administration. Bulletin of Experimental Biology and Medicine 170:1, pages 24-29.
Crossref
Dong-Hyuk Cho, I-Rang Lim, Jong-Ho Kim, Mi-Na Kim, Yong-Hyun Kim, Kyong Hwa Park, Seong-Mi Park & Wan Joo Shim. (2020) Protective Effects of Statin and Angiotensin Receptor Blocker in a Rat Model of Doxorubicin- and Trastuzumab-Induced Cardiomyopathy. Journal of the American Society of Echocardiography 33:10, pages 1253-1263.
Crossref
N.V. Tursunova, M.G. Klinnikova, O.A. Babenko & E.L. Lushnikova. (2020) Molecular mechanisms of the cardiotoxic action of anthracycline antibiotics and statin-induced cytoprotective reactions of cardiomyocytes. Biomeditsinskaya Khimiya 66:5, pages 357-371.
Crossref
Keith Dadson, Oscar Calvillo-Argüelles, Paaladinesh Thavendiranathan & Filio Billia. (2020) Anthracycline-induced cardiomyopathy: cellular and molecular mechanisms. Clinical Science 134:13, pages 1859-1885.
Crossref
Kerstin N. Timm & Damian J. Tyler. (2020) The Role of AMPK Activation for Cardioprotection in Doxorubicin-Induced Cardiotoxicity. Cardiovascular Drugs and Therapy 34:2, pages 255-269.
Crossref
Maryam Nabati, Ghasem Janbabai, Jamil Esmailian & Jamshid Yazdani. (2019) Effect of Rosuvastatin in Preventing Chemotherapy-Induced Cardiotoxicity in Women With Breast Cancer: A Randomized, Single-Blind, Placebo-Controlled Trial. Journal of Cardiovascular Pharmacology and Therapeutics 24:3, pages 233-241.
Crossref
Atanur KURU, Uğur YAZAR, Süleyman Caner KARAHAN, İsmail SAYGIN & Serap ÖZER YAMAN. (2018) Sıçanlarda Deneysel Spinal Kord İskemi/Reperfüzyon Yaralanmasında Karvedilol’un Etkileri. Bozok Tıp Dergisi.
Crossref
Haiyan Zhang, Xiang Lu, Zhengxia Liu & Kang Du. (2018) Rosuvastatin reduces the pro-inflammatory effects of adriamycin on the expression of HMGB1 and RAGE in rats. International Journal of Molecular Medicine.
Crossref
Hanaa S.E. Mousa, Sara M. Abdel Aal & Noha A.T. Abbas. (2018) Umbilical cord blood-mesenchymal stem cells and carvedilol reduce doxorubicin- induced cardiotoxicity: Possible role of insulin-like growth factor-1. Biomedicine & Pharmacotherapy 105, pages 1192-1204.
Crossref
Takehiro Nakahara, Takashi Tanimoto, Artiom D. Petrov, Kiyotake Ishikawa, H. William Strauss & Jagat Narula. 2018. Experimental Models of Cardiovascular Diseases. Experimental Models of Cardiovascular Diseases 221 232 .
Ahmed M. Kabel & Abeer A. Elkhoely. (2017) Targeting proinflammatory cytokines, oxidative stress, TGF-β1 and STAT-3 by rosuvastatin and ubiquinone to ameliorate trastuzumab cardiotoxicity. Biomedicine & Pharmacotherapy 93, pages 17-26.
Crossref
Christian Henninger & Gerhard Fritz. (2017) Statins in anthracycline-induced cardiotoxicity: Rac and Rho, and the heartbreakers. Cell Death & Disease 8:1, pages e2564-e2564.
Crossref
M. Scherrer-Crosbie. 2017. Anti-Cancer Treatments and Cardiotoxicity. Anti-Cancer Treatments and Cardiotoxicity 401 407 .
Nagla A. El-Shitany & Karema El-Desoky. (2016) Protective Effects of Carvedilol and Vitamin C against Azithromycin-Induced Cardiotoxicity in Rats via Decreasing ROS, IL1- β , and TNF- α Production and Inhibiting NF- κ B and Caspase-3 Expression . Oxidative Medicine and Cellular Longevity 2016, pages 1-13.
Crossref
Jie Deng, Guijun Wu, Chen Yang, Yi Li, Quanmin Jing & Yaling Han. (2015) Rosuvastatin attenuates contrast-induced nephropathy through modulation of nitric oxide, inflammatory responses, oxidative stress and apoptosis in diabetic male rats. Journal of Translational Medicine 13:1.
Crossref
Ibrahim Elmadbouh, Magda Mansour, Mohamed Nabeh, Walaa Faried, Ahmed Abdelsabour & Adel Omar. (2015) Atorvastatin improves cardiac function and remodeling in chronic non-ischemic heart failure: A clinical and pre-clinical study. The Egyptian Heart Journal 67:4, pages 289-298.
Crossref
Nieves Montoro & Jose Luis López-Sendón. (2015) Heart failure years after cancer treatment. Future Cardiology 11:4, pages 433-440.
Crossref
P.C. Orsolin, R.G. Silva-Oliveira & J.C. Nepomuceno. (2015) Modulating effect of synthetic statins against damage induced by doxorubicin in somatic cells of Drosophila melanogaster. Food and Chemical Toxicology 81, pages 111-119.
Crossref
B. Polat, Halis Suleyman, E. Sener & F. Akcay. (2014) Examination of the Effects of Thiamine and Thiamine Pyrophosphate on Doxorubicin-Induced Experimental Cardiotoxicity. Journal of Cardiovascular Pharmacology and Therapeutics 20:2, pages 221-229.
Crossref
Da Liu, Ying Huang, Bin Li, Changqing Jia, Feng Liang & Qin Fu. (2015) Carvedilol promotes neurological function, reduces bone loss and attenuates cell damage after acute spinal cord injury in rats. Clinical and Experimental Pharmacology and Physiology 42:2, pages 202-212.
Crossref
Mohamed A. El-Moselhy & Azza A.K. El-Sheikh. (2014) Protective mechanisms of atorvastatin against doxorubicin-induced hepato-renal toxicity. Biomedicine & Pharmacotherapy 68:1, pages 101-110.
Crossref
Raimundo Fernandes de Araújo Júnior, Tatiana Oliveira Souza, Caroline Addison Xavier de Medeiros, Lélia Batista de Souza, Maria de Lourdes Freitas, Hévio Freitas de Lucena, Maria do Socorro Costa Feitosa Alves & Aurigena Antunes de Araújo. (2013) Carvedilol Decrease IL-1β and TNF-α, Inhibits MMP-2, MMP-9, COX-2, and RANKL Expression, and Up-Regulates OPG in a Rat Model of Periodontitis. PLoS ONE 8:7, pages e66391.
Crossref
Beyzagul Polat, Elif Cadirci, Zekai Halici, Yasin Bayir, Deniz Unal, Bulent Caglar Bilgin, Tugba Nurcan Yuksel & Serhat Vancelik. (2013) The protective effect of amiodarone in lung tissue of cecal ligation and puncture-induced septic rats: a perspective from inflammatory cytokine release and oxidative stress. Naunyn-Schmiedeberg's Archives of Pharmacology 386:7, pages 635-643.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.