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Research Article

The evaluation of the reactivating and therapeutic efficacy of two novel oximes (K361 and K378) in comparison with the oxime K203 and trimedoxime in tabun-poisoned rats and mice

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Pages 173-178 | Received 28 May 2013, Accepted 29 Nov 2013, Published online: 03 Dec 2013

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Maria Arshad, Muhammad Qaiser Fatmi, Kamil Musilek, Alamdar Hussain, Kamil Kuca, Georg Petroianu, Huba Kalasz & Syed Muhammad Nurulain. (2018) In silico and in vitro evaluation of two novel oximes (K378 and K727) in comparison to K-27 and pralidoxime against paraoxon-ethyl intoxication. Toxicology Mechanisms and Methods 28:1, pages 62-68.
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Jiri Kassa, Jan Misik, Jana Hatlapatkova & Jana Zdarova Karasova. (2017) A comparison of neuroprotective efficacy of two novel reactivators of acetylcholinesterase called K920 and K923 with the oxime K203 and trimedoxime in tabun-poisoned rats. Toxicology Mechanisms and Methods 27:3, pages 236-243.
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Jiri Kassa, Vendula Sepsova, Lenka Matouskova, Anna Horova & Kamil Musilek. (2015) A comparison of the reactivating and therapeutic efficacy of two novel bispyridinium oximes (K727, K733) with the oxime HI-6 and obidoxime in sarin-poisoned rats and mice. Toxicology Mechanisms and Methods 25:3, pages 229-233.
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Articles from other publishers (3)

Vendula Hepnarova, Lubica Muckova, Avi Ring, Jaroslav Pejchal, David Herman, Jan Misik, Martina Hrabinova, Daniel Jun & Ondrej Soukup. (2019) Pharmacological and toxicological in vitro and in vivo effect of higher doses of oxime reactivators. Toxicology and Applied Pharmacology 383, pages 114776.
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Lukas Gorecki, Ondrej Soukup, Tomas Kucera, David Malinak, Daniel Jun, Kamil Kuca, Kamil Musilek & Jan Korabecny. (2018) Oxime K203: a drug candidate for the treatment of tabun intoxication. Archives of Toxicology 93:3, pages 673-691.
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Jiri Kassa, Jan Misik & Jana Zdarova Karasova. (2015) Neuroprotective efficacy of newly developed oximes in comparison with currently available oximes in tabun-poisoned rats. Journal of Applied Biomedicine 13:1, pages 39-46.
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