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ORIGINAL RESEARCH

Antioxidant Diet Protects Against Emphysema, but Increases Mortality in Cigarette Smoke-Exposed Mice

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Pages 362-368 | Published online: 11 Aug 2011

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Jun-Ho Jang, Hitendra S. Chand, Shannon Bruse, Melanie Doyle-Eisele, Christopher Royer, Jacob McDonald, Clifford Qualls, Aloysius J. Klingelhutz, Yong Lin, Rama Mallampalli, Yohannes Tesfaigzi & Toru Nyunoya. (2017) Connective Tissue Growth Factor Promotes Pulmonary Epithelial Cell Senescence and Is Associated with COPD Severity. COPD: Journal of Chronic Obstructive Pulmonary Disease 14:2, pages 228-237.
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Wolfgang Domej, Karl Oettl & Wilfried Renner. (2014) Oxidative stress and free radicals in COPD – implications and relevance for treatment. International Journal of Chronic Obstructive Pulmonary Disease 9, pages 1207-1224.
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Giusy Daniela Albano, Rosalia Paola Gagliardo, Angela Marina Montalbano & Mirella Profita. (2022) Overview of the Mechanisms of Oxidative Stress: Impact in Inflammation of the Airway Diseases. Antioxidants 11:11, pages 2237.
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Mark A. Sussman. (2022) VAPIng into ARDS: Acute Respiratory Distress Syndrome and Cardiopulmonary Failure. Pharmacology & Therapeutics 232, pages 108006.
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Tatiana Victoni, Emiliano Barreto, Vincent Lagente & Vinicius F. Carvalho. (2021) Oxidative Imbalance as a Crucial Factor in Inflammatory Lung Diseases: Could Antioxidant Treatment Constitute a New Therapeutic Strategy?. Oxidative Medicine and Cellular Longevity 2021, pages 1-11.
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Rama K. Mallampalli, Xiuying Li, Jun-Ho Jang, Tomasz Kaminski, Aki Hoji, Tiffany Coon, Divay Chandra, Starr Welty, Yaqun Teng, John Sembrat, Mauricio Rojas, Yutong Zhao, Robert Lafyatis, Chunbin Zou, Frank Sciurba, Prithu Sundd, Li Lan & Toru Nyunoya. (2020) Cigarette smoke exposure enhances transforming acidic coiled-coil–containing protein 2 turnover and thereby promotes emphysema. JCI Insight 5:2.
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Samantha J. Snow & Urmila P. Kodavanti. 2019. Biomarkers in Toxicology. Biomarkers in Toxicology 229 250 .
Dejan Milatovic & Ramesh C. Gupta. 2019. Nutraceuticals in Veterinary Medicine. Nutraceuticals in Veterinary Medicine 205 213 .
Andrew J. Jang, Ji-Hyeok Lee, Mari Yotsu-Yamashita, Joodong Park, Steve Kye, Raymond L. Benza, Michael J. Passineau, You-Jin Jeon & Toru Nyunoya. (2018) A Novel Compound, “FA-1” Isolated from Prunus mume, Protects Human Bronchial Epithelial Cells and Keratinocytes from Cigarette Smoke Extract-Induced Damage. Scientific Reports 8:1.
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Robert P. Young & Raewyn J. Hopkins. (2018) Is the “Western Diet” a New Smoking Gun for Chronic Obstructive Pulmonary Disease?. Annals of the American Thoracic Society 15:6, pages 662-663.
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Catherine R. Sears, Huaxin Zhou, Matthew J. Justice, Amanda J. Fisher, Jacob Saliba, Isaac Lamb, Jessica Wicker, Kelly S. Schweitzer & Irina Petrache. (2018) Xeroderma Pigmentosum Group C Deficiency Alters Cigarette Smoke DNA Damage Cell Fate and Accelerates Emphysema Development. American Journal of Respiratory Cell and Molecular Biology 58:3, pages 402-411.
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Yohannes A. Mebratu, Kevin R. Smith, Getahun E. Agga & Yohannes Tesfaigzi. (2016) Inflammation and emphysema in cigarette smoke-exposed mice when instilled with poly (I:C) or infected with influenza A or respiratory syncytial viruses. Respiratory Research 17:1.
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Li Zuo, Chia-Chen Chuang & Tingyang Zhou. 2016. Reactive Oxygen Species in Biology and Human Health. Reactive Oxygen Species in Biology and Human Health 399 407 .
P. Padmini S.J. Khedoe, Patrick C.N. Rensen, Jimmy F.P. Berbée & Pieter S. Hiemstra. (2016) Murine models of cardiovascular comorbidity in chronic obstructive pulmonary disease. American Journal of Physiology-Lung Cellular and Molecular Physiology 310:11, pages L1011-L1027.
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Galina F. Fedorova, Vessela D. Kancheva, Valery A. Menshov, Vladimir V. Naumov, Rostislav F. Vasil’ev, Timur L. Veprintsev, Aleksei V. Trofimov, Yuri B. Tsaplev & Olga I. Yablonskaya. 2016. 357 385 .
Elias G. Awji, Jean Clare Seagrave & Yohannes Tesfaigzi. (2015) Correlation of Cigarette Smoke-Induced Pulmonary Inflammation and Emphysema in C3H and C57Bl/6 Mice. Toxicological Sciences 147:1, pages 75-83.
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Francesca Polverino, Melanie Doyle-Eisele, Jacob McDonald, Julie A. Wilder, Christopher Royer, Maria Laucho-Contreras, Emer M. Kelly, Miguel Divo, Victor Pinto-Plata, Joe Mauderly, Bartolome R. Celli, Yohannes Tesfaigzi & Caroline A. Owen. (2015) A Novel Nonhuman Primate Model of Cigarette Smoke–Induced Airway Disease. The American Journal of Pathology 185:3, pages 741-755.
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Urmila P. Kodavanti. 2014. Biomarkers in Toxicology. Biomarkers in Toxicology 217 239 .
Qiong Wang, Wenshu Chen, Xiuling Xu, Bilan Li, Weiyang He, Mabel T. Padilla, Jun-Ho Jang, Toru Nyunoya, Shantu Amin, Xia Wang & Yong Lin. (2013) RIP1 potentiates BPDE-induced transformation in human bronchial epithelial cells through catalase-mediated suppression of excessive reactive oxygen species. Carcinogenesis 34:9, pages 2119-2128.
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Chien-Kai Wang, Hui-Ling Lee, Han Chang, Ming-Hsien Tsai, Yu-Chun Kuo & Pinpin Lin. (2012) Enhancement between environmental tobacco smoke and arsenic on emphysema-like lesions in mice. Journal of Hazardous Materials 221-222, pages 256-263.
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